ATE192485T1 - 4-0-methyl-transferas codierende dna sequenz - Google Patents
4-0-methyl-transferas codierende dna sequenzInfo
- Publication number
- ATE192485T1 ATE192485T1 AT92925104T AT92925104T ATE192485T1 AT E192485 T1 ATE192485 T1 AT E192485T1 AT 92925104 T AT92925104 T AT 92925104T AT 92925104 T AT92925104 T AT 92925104T AT E192485 T1 ATE192485 T1 AT E192485T1
- Authority
- AT
- Austria
- Prior art keywords
- transferas
- methyl
- coding sequence
- dna coding
- host
- Prior art date
Links
- 108091026890 Coding region Proteins 0.000 title 1
- STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 abstract 1
- 108010073360 Carminomycin 4-O-methyltransferase Proteins 0.000 abstract 1
- 229930188550 carminomycin Natural products 0.000 abstract 1
- XREUEWVEMYWFFA-CSKJXFQVSA-N carminomycin Chemical compound C1[C@H](N)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1C2=C(O)C(C(=O)C3=C(O)C=CC=C3C3=O)=C3C(O)=C2C[C@@](O)(C(C)=O)C1 XREUEWVEMYWFFA-CSKJXFQVSA-N 0.000 abstract 1
- XREUEWVEMYWFFA-UHFFFAOYSA-N carminomycin I Natural products C1C(N)C(O)C(C)OC1OC1C2=C(O)C(C(=O)C3=C(O)C=CC=C3C3=O)=C3C(O)=C2CC(O)(C(C)=O)C1 XREUEWVEMYWFFA-UHFFFAOYSA-N 0.000 abstract 1
- 229950001725 carubicin Drugs 0.000 abstract 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
- 229960000975 daunorubicin Drugs 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79387391A | 1991-11-18 | 1991-11-18 | |
| US07/959,941 US5364781A (en) | 1991-11-18 | 1992-10-09 | Process for preparing daunorubicin |
| PCT/US1992/009580 WO1993010223A1 (en) | 1991-11-18 | 1992-11-17 | Dna-sequence coding for carminomycin 4-o-methyltransferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE192485T1 true ATE192485T1 (de) | 2000-05-15 |
Family
ID=27121440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92925104T ATE192485T1 (de) | 1991-11-18 | 1992-11-17 | 4-0-methyl-transferas codierende dna sequenz |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5563064A (de) |
| EP (1) | EP0567630B1 (de) |
| JP (1) | JP3361522B2 (de) |
| AT (1) | ATE192485T1 (de) |
| AU (1) | AU666344B2 (de) |
| CA (1) | CA2100334C (de) |
| DE (1) | DE69230997T2 (de) |
| ES (1) | ES2148183T3 (de) |
| FI (1) | FI111012B (de) |
| HU (1) | HU214354B (de) |
| IL (1) | IL103766A (de) |
| MX (1) | MX9206586A (de) |
| NZ (1) | NZ245124A (de) |
| WO (1) | WO1993010223A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI944556A0 (fi) * | 1994-09-30 | 1994-09-30 | Kristiina Ylihonko | Foerfarande foer producering av antracykliner och deras mellanprodukter |
| GB2302540B (en) * | 1995-06-23 | 1999-02-24 | Pharmacia Spa | Cofactor for transmethylation |
| US5652125A (en) * | 1996-06-10 | 1997-07-29 | Pharmacia S.P.A. | Process for preparing daunorubicin |
| US6312920B1 (en) | 1996-11-13 | 2001-11-06 | Eli Lilly And Company | SAM operon |
| WO1998039458A1 (en) * | 1997-03-06 | 1998-09-11 | Pharmacia & Upjohn S.P.A. | Process for preparing doxorubicin |
| US5976836A (en) * | 1997-05-07 | 1999-11-02 | Fermalogic, Inc. | Methods and compositions for enhancing erythromycin production |
| CN112080454B (zh) * | 2020-09-01 | 2022-07-08 | 浙江大学 | 一株产柔红霉素的工程链霉菌及其构建方法 |
| CN114457101B (zh) * | 2022-01-12 | 2024-01-12 | 安徽大学 | 通过改造糖多孢红霉菌sace_1558基因提高红霉素产量的方法及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364781A (en) * | 1991-11-18 | 1994-11-15 | Farmitalia Carlo Erba S.R.L | Process for preparing daunorubicin |
-
1992
- 1992-11-13 NZ NZ245124A patent/NZ245124A/en not_active IP Right Cessation
- 1992-11-16 MX MX9206586A patent/MX9206586A/es not_active IP Right Cessation
- 1992-11-17 WO PCT/US1992/009580 patent/WO1993010223A1/en not_active Ceased
- 1992-11-17 CA CA002100334A patent/CA2100334C/en not_active Expired - Fee Related
- 1992-11-17 JP JP50933293A patent/JP3361522B2/ja not_active Expired - Fee Related
- 1992-11-17 AU AU31290/93A patent/AU666344B2/en not_active Ceased
- 1992-11-17 HU HU9302362A patent/HU214354B/hu not_active IP Right Cessation
- 1992-11-17 AT AT92925104T patent/ATE192485T1/de not_active IP Right Cessation
- 1992-11-17 ES ES92925104T patent/ES2148183T3/es not_active Expired - Lifetime
- 1992-11-17 IL IL10376692A patent/IL103766A/xx not_active IP Right Cessation
- 1992-11-17 DE DE69230997T patent/DE69230997T2/de not_active Expired - Fee Related
- 1992-11-17 EP EP92925104A patent/EP0567630B1/de not_active Expired - Lifetime
-
1993
- 1993-07-14 FI FI933200A patent/FI111012B/fi active
-
1994
- 1994-06-15 US US08/259,924 patent/US5563064A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU3129093A (en) | 1993-06-15 |
| MX9206586A (es) | 1994-07-29 |
| US5563064A (en) | 1996-10-08 |
| JPH06505402A (ja) | 1994-06-23 |
| EP0567630A1 (de) | 1993-11-03 |
| EP0567630B1 (de) | 2000-05-03 |
| NZ245124A (en) | 1994-06-27 |
| JP3361522B2 (ja) | 2003-01-07 |
| IL103766A0 (en) | 1993-04-04 |
| FI933200L (fi) | 1993-08-18 |
| CA2100334C (en) | 2005-05-24 |
| IL103766A (en) | 2000-12-06 |
| WO1993010223A1 (en) | 1993-05-27 |
| DE69230997T2 (de) | 2000-08-17 |
| CA2100334A1 (en) | 1993-05-19 |
| HUT69768A (en) | 1995-09-28 |
| ES2148183T3 (es) | 2000-10-16 |
| FI933200A0 (fi) | 1993-07-14 |
| DE69230997D1 (de) | 2000-06-08 |
| HU9302362D0 (en) | 1993-11-29 |
| FI111012B (fi) | 2003-05-15 |
| HU214354B (hu) | 1998-03-30 |
| AU666344B2 (en) | 1996-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |