IL103731A0 - Lupane derivatives,their preparation and pharmceutical compositions which contain them - Google Patents

Lupane derivatives,their preparation and pharmceutical compositions which contain them

Info

Publication number
IL103731A0
IL103731A0 IL103731A IL10373192A IL103731A0 IL 103731 A0 IL103731 A0 IL 103731A0 IL 103731 A IL103731 A IL 103731A IL 10373192 A IL10373192 A IL 10373192A IL 103731 A0 IL103731 A0 IL 103731A0
Authority
IL
Israel
Prior art keywords
contain
preparation
lupane derivatives
pharmceutical compositions
pharmceutical
Prior art date
Application number
IL103731A
Other languages
English (en)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL103731A0 publication Critical patent/IL103731A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL103731A 1991-11-13 1992-11-12 Lupane derivatives,their preparation and pharmceutical compositions which contain them IL103731A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9113907A FR2683531B1 (fr) 1991-11-13 1991-11-13 Nouveaux derives du lupane, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
IL103731A0 true IL103731A0 (en) 1993-04-04

Family

ID=9418832

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103731A IL103731A0 (en) 1991-11-13 1992-11-12 Lupane derivatives,their preparation and pharmceutical compositions which contain them

Country Status (11)

Country Link
US (1) US5468888A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0542622A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2121692A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI942181A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2683531B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUT66959A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL103731A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9206503A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW224103B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1993010142A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU97492A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
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US5962527A (en) * 1995-03-21 1999-10-05 The Board Of Trustees Of The University Of Illinois Method and composition for treating cancers
US5658947A (en) * 1995-03-21 1997-08-19 Board Of Trustees Of The University Of Illinois Method and composition for selectively inhibiting melanoma using betalinic acid
US5679828A (en) * 1995-06-05 1997-10-21 Biotech Research Labs, Inc. Betulinic acid and dihydrobetulinic acid derivatives and uses therefor
WO1998055497A1 (en) 1997-06-04 1998-12-10 Cornell Research Foundation, Inc. Betulinol derivatives
US6403816B1 (en) * 1997-09-30 2002-06-11 Dabur Research Foundation Betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis
US6172110B1 (en) * 1998-03-02 2001-01-09 The University Of North Carolina At Chapel Hill Acylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
US6369101B1 (en) 1999-02-26 2002-04-09 Regents Of The University Of Minnesota Therapeutic method to treat herpes virus infection
US6392070B1 (en) 1999-08-10 2002-05-21 Regents Of The University Of Minnesota Birch bark processing and the isolation of natural products from birch bark
EP1218402B1 (en) * 1999-09-09 2004-05-26 Dabur Research Foundation Novel betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis
CA2418479C (en) * 2000-08-18 2007-12-18 The Board Of Trustees Of The University Of Illinois Prodrugs of betulinic acid derivatives for the treatment of cancer
US7488722B2 (en) * 2001-05-11 2009-02-10 University Of Ottawa Anxiolytic Marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
GB0128071D0 (en) * 2001-11-22 2002-01-16 Cyclacel Ltd Medicament
RU2211843C1 (ru) * 2002-01-25 2003-09-10 Новосибирский институт органической химии им. Н.Н.Ворожцова СО РАН N'-{n-[3-оксо-20(29)-лупен-28-оил]-9-аминононаноил}-3-амино-3-фенилпропио новая кислота, обладающая иммуностимулирующей и противовирусной активностью
CA2514563A1 (en) * 2003-01-29 2004-08-19 Panacos Pharmaceuticals, Inc. Inhibition of hiv-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein
US7537765B2 (en) * 2003-01-29 2009-05-26 Panacos Pharmaceuticals, Inc. Inhibition of HIV-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein
US7026305B2 (en) * 2003-04-14 2006-04-11 Meharry Medical College Anti-HIV agents with dual sites of action
US7326717B2 (en) * 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
US20050239748A1 (en) * 2004-03-17 2005-10-27 Panacos Pharmaceuticals, Inc. Pharmaceutical salts of 3-O-(3',3'-dimethylsuccinyl) betulinic acid
US20060019934A1 (en) * 2004-05-20 2006-01-26 Saxena Brij B Anti-HIV-1 activity of betulinol derivatives
US7282521B2 (en) * 2004-05-24 2007-10-16 University Of North Carolina At Chapel Hill Anti-retroviral moronic acid derivatives
WO2006031756A2 (en) * 2004-09-10 2006-03-23 Cornell Research Foundation, Inc Betulinol derivatives as anti-cancer agents
TW200628161A (en) * 2004-11-12 2006-08-16 Panacos Pharmaceuticals Inc Novel betulin derivatives, preparation thereof and use thereof
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
AU2006235486A1 (en) 2005-04-12 2006-10-19 Panacos Pharmaceuticals, Inc. Polymorphs of 3-o-(3',3'-dimethylsuccinyl) betulinic acid di-N-methyl-D-glucamine
US20090149429A1 (en) * 2005-06-22 2009-06-11 Myriad Genetics, Incorporated Antiviral compounds
WO2007098247A2 (en) * 2006-02-21 2007-08-30 Achillion Pharmaceuticals, Inc. Substituted taraxastanes useful for treating viral infections
US20080039428A1 (en) * 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
US20110144069A1 (en) * 2006-10-16 2011-06-16 Myriad Genetics, Incorporated Compounds for treating viral infections
RU2317996C1 (ru) * 2006-10-30 2008-02-27 Институт нефтехимии и катализа РАН N'-{n-[3-оксо-лупан-28-оил]-9-аминононаноил}-3-амино-3-фенил-пропионовая кислота и ее соли как противовирусные и иммуностимулирующие агенты
WO2009020732A1 (en) * 2007-08-03 2009-02-12 Advanced Life Sciences, Inc. Lupane-type triterpenoids modified at 30-position and analogues thereof
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
RU2353623C1 (ru) * 2007-09-17 2009-04-27 Новосибирский институт органической химии им. Н.Н. Ворожцова СО РАН (НИОХ СО РАН) Корректор цитостатической полихимиотерапии
RU2357973C1 (ru) * 2007-09-26 2009-06-10 ИНСТИТУТ НЕФТЕХИМИИ И КАТАЛИЗА Российской Академии Наук Способ получения дипептидов лупанового ряда
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
FR2929117B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association du 2,4-diaminopyrimidine 3-n-oxyde et du madecassosside et/ou du terminoloside pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
FR2929118B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association de madecassoside et/ou de terminoloside et d'une arginine pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
KR100941595B1 (ko) * 2008-06-05 2010-02-11 주식회사 알앤엘바이오 바이러스 억제제로서 유용한 트리테르페노이드계 화합물
RU2385324C1 (ru) * 2008-07-07 2010-03-27 Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) (статус государственного учреждения) Корректор паранеопластических повреждений и токсических эффектов цитостатической полихимиотерапии
FR2949052B1 (fr) 2009-08-13 2015-03-27 Oreal Procede de traitement cosmetique du cuir chevelu.
CN102558280B (zh) * 2011-11-18 2014-09-17 温州大学 一种30-卤代桦木酸的生产方法
EP2838533B1 (en) 2012-04-16 2017-10-04 Case Western Reserve University Compositions and methods of modulating 15-pgdh activity
WO2014123889A1 (en) * 2013-02-06 2014-08-14 Bristol-Myers Squibb Company C-19 modified triterpenoids with hiv maturation inhibitory activity
EP3057973B1 (en) 2013-10-15 2019-09-04 Case Western Reserve University Compositions comprising a 15-pgdh inhibitor for the healing of wounds
CN104045680B (zh) 2014-06-20 2016-09-14 东北林业大学 桦木醇的乙酰氨基酸酰类衍生物及其制备方法
EP3226859B1 (en) 2014-12-05 2025-03-26 Case Western Reserve University Akr1a1 inhibitors for use in lowering cholesterol and modulate s-nitrosylation
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
US10688037B1 (en) 2015-12-31 2020-06-23 Nutraceutical Wellness Inc. Compositions and method for hair regrowth
JP7595413B2 (ja) 2016-11-30 2024-12-06 ケース ウエスタン リザーブ ユニバーシティ １５－ｐｇｄｈ阻害剤とコルチコステロイドおよび／またはｔｎｆ阻害剤との組み合わせならびにその使用
JP2020514323A (ja) 2017-02-06 2020-05-21 ケース ウエスタン リザーブ ユニバーシティ 短鎖デヒドロゲナーゼ活性を調節する組成物と方法
PL237998B1 (pl) 2018-05-28 2021-06-28 Narodowy Inst Lekow Fosfonowe pochodne kwasu 3-karboksyacylobetulinowego, sposób ich otrzymywania oraz ich zastosowanie
CN120463721A (zh) 2018-11-21 2025-08-12 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
CA3183262A1 (en) 2020-05-20 2021-11-25 Rodeo Therapeutics Corporation Compositions and methods of modulating short-chain dehydrogenase activity

Also Published As

Publication number Publication date
FR2683531A1 (fr) 1993-05-14
WO1993010142A1 (fr) 1993-05-27
TW224103B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-05-21
FR2683531B1 (fr) 1993-12-31
YU97492A (sh) 1995-12-04
EP0542622A1 (fr) 1993-05-19
US5468888A (en) 1995-11-21
CA2121692A1 (fr) 1993-05-27
EP0613483A1 (fr) 1994-09-07
MX9206503A (es) 1993-05-01
FI942181A7 (fi) 1994-05-11
HU9401353D0 (en) 1994-08-29
HUT66959A (en) 1995-01-30
FI942181A0 (fi) 1994-05-11

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