IL103513A - History of Adenosine N - 2 - Dual-Transformed, Preparation and Pharmaceutical Preparations Containing Them - Google Patents

History of Adenosine N - 2 - Dual-Transformed, Preparation and Pharmaceutical Preparations Containing Them

Info

Publication number
IL103513A
IL103513A IL10351392A IL10351392A IL103513A IL 103513 A IL103513 A IL 103513A IL 10351392 A IL10351392 A IL 10351392A IL 10351392 A IL10351392 A IL 10351392A IL 103513 A IL103513 A IL 103513A
Authority
IL
Israel
Prior art keywords
compound
formula
set forth
adenosine
forth above
Prior art date
Application number
IL10351392A
Other languages
English (en)
Hebrew (he)
Other versions
IL103513A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL103513A0 publication Critical patent/IL103513A0/xx
Publication of IL103513A publication Critical patent/IL103513A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL10351392A 1991-10-24 1992-10-22 History of Adenosine N - 2 - Dual-Transformed, Preparation and Pharmaceutical Preparations Containing Them IL103513A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK9100324 1991-10-24

Publications (2)

Publication Number Publication Date
IL103513A0 IL103513A0 (en) 1993-03-15
IL103513A true IL103513A (en) 1996-09-12

Family

ID=8153695

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10351392A IL103513A (en) 1991-10-24 1992-10-22 History of Adenosine N - 2 - Dual-Transformed, Preparation and Pharmaceutical Preparations Containing Them

Country Status (11)

Country Link
US (2) US5432164A (no)
EP (1) EP0609375A1 (no)
JP (1) JPH07500586A (no)
AU (1) AU657374B2 (no)
CA (1) CA2121844A1 (no)
FI (1) FI941876A (no)
IL (1) IL103513A (no)
NO (1) NO300461B1 (no)
NZ (1) NZ244875A (no)
WO (1) WO1993008206A1 (no)
ZA (1) ZA928222B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432164A (en) * 1991-10-24 1995-07-11 Novo Nordisk A/S C2,N6 -disubstituted adenosine derivatives
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
EP0704215A3 (en) * 1994-06-02 1998-04-01 Takeda Chemical Industries, Ltd. Inhibitor of vascular permeability enhancer
WO1997033591A1 (en) * 1996-03-13 1997-09-18 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
AU2022497A (en) * 1996-03-13 1997-10-01 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
US5789416B1 (en) * 1996-08-27 1999-10-05 Cv Therapeutics Inc N6 mono heterocyclic substituted adenosine derivatives
AU4377397A (en) * 1996-10-14 1998-05-11 Novo Nordisk A/S Novel therapeutically active adenosine derivatives
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
US6175004B1 (en) * 1998-09-01 2001-01-16 Isis Pharmaceuticals, Inc. Process for the synthesis of oligonucleotides incorporating 2-aminoadenosine
US6576619B2 (en) 1999-05-24 2003-06-10 Cv Therapeutics, Inc. Orally active A1 adenosine receptor agonists
US6294522B1 (en) * 1999-12-03 2001-09-25 Cv Therapeutics, Inc. N6 heterocyclic 8-modified adenosine derivatives
US7342003B2 (en) * 2001-10-25 2008-03-11 King Pharmaceuticals Research And Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
CA2515068A1 (en) * 2003-02-03 2004-08-19 Cv Therapeutics Inc. Partial and full agonists of a1 adenosine receptors
WO2005033121A2 (en) * 2003-10-03 2005-04-14 King Pharmaceuticals Research & Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
WO2007107598A1 (en) 2006-03-21 2007-09-27 Heinrich-Heine-Universität Düsseldorf Phosphorylated a2a receptor agonists
MX361102B (es) 2013-12-19 2018-11-27 Procter & Gamble Modelado de fibras de queratina con el uso de un agente activo que comprende al menos dos grupos funcionales seleccionados de: -c(oh)- y -c(=o)oh.
MX2017008204A (es) 2014-12-19 2017-10-06 Procter & Gamble Conformacion de las fibras de queratina mediante el uso de arabinosa y carbonato de etileno.
EP3297730A1 (en) 2014-12-19 2018-03-28 The Procter and Gamble Company Method of shaping keratin fibres

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796700A (en) * 1970-06-30 1974-03-12 Takedo Chem Ind Ltd Adenosine derivatives and the production thereof
JPH0696534B2 (ja) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 抗痴呆剤
US5017578A (en) * 1989-06-09 1991-05-21 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents
PT95628A (pt) * 1989-10-19 1991-09-30 Searle & Co Metodo de tratamento de perturbacoes de mobilidade gastrointestinal com composto de adenosina
US5432164A (en) * 1991-10-24 1995-07-11 Novo Nordisk A/S C2,N6 -disubstituted adenosine derivatives

Also Published As

Publication number Publication date
US5432164A (en) 1995-07-11
IL103513A0 (en) 1993-03-15
CA2121844A1 (en) 1993-04-29
NZ244875A (en) 1995-04-27
WO1993008206A1 (en) 1993-04-29
NO941477D0 (no) 1994-04-22
AU2916092A (en) 1993-05-21
FI941876A (fi) 1994-06-22
JPH07500586A (ja) 1995-01-19
EP0609375A1 (en) 1994-08-10
AU657374B2 (en) 1995-03-09
US5578582A (en) 1996-11-26
FI941876A0 (fi) 1994-04-22
NO941477L (no) 1994-06-23
ZA928222B (en) 1994-04-25
NO300461B1 (no) 1997-06-02

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US5430027A (en) 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias
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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void