IL103082A0 - Tricyclic heterocycles - Google Patents
Tricyclic heterocyclesInfo
- Publication number
- IL103082A0 IL103082A0 IL103082A IL10308292A IL103082A0 IL 103082 A0 IL103082 A0 IL 103082A0 IL 103082 A IL103082 A IL 103082A IL 10308292 A IL10308292 A IL 10308292A IL 103082 A0 IL103082 A0 IL 103082A0
- Authority
- IL
- Israel
- Prior art keywords
- tricyclic heterocycles
- methylene
- formula
- relates
- substituents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919120640A GB9120640D0 (en) | 1991-09-27 | 1991-09-27 | Tricyclic heterocycles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL103082A0 true IL103082A0 (en) | 1993-02-21 |
Family
ID=10702122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL103082A IL103082A0 (en) | 1991-09-27 | 1992-09-07 | Tricyclic heterocycles |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5317101A (fi) |
| EP (1) | EP0534667B1 (fi) |
| JP (1) | JPH05230055A (fi) |
| KR (1) | KR930006014A (fi) |
| AT (1) | ATE148700T1 (fi) |
| AU (1) | AU2217992A (fi) |
| CA (1) | CA2078401A1 (fi) |
| CZ (1) | CZ292092A3 (fi) |
| DE (1) | DE69217312T2 (fi) |
| FI (1) | FI924300A (fi) |
| GB (2) | GB9120640D0 (fi) |
| HU (1) | HU9203002D0 (fi) |
| IL (1) | IL103082A0 (fi) |
| NO (1) | NO923736L (fi) |
| TW (1) | TW224972B (fi) |
| ZA (1) | ZA926783B (fi) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5550122A (en) * | 1989-08-29 | 1996-08-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pyrido[2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and thiones and their use on the treatment of HIV infection |
| US5304644A (en) * | 1992-04-15 | 1994-04-19 | G. D. Searle & Co. | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
| US5449673A (en) * | 1992-08-13 | 1995-09-12 | G. D. Searle & Co. | 10,11-dihydro-10-(3-substituted-1-oxo-2-propyl, propenyl or propynyl)dibenz[b,f][1,4] oxazepine prostaglandin antagonists |
| US5420123A (en) * | 1992-12-21 | 1995-05-30 | Bristol-Myers Squibb Company | Dibenzodiazepine endothelin antagonists |
| US5395932A (en) * | 1993-04-30 | 1995-03-07 | G. D. Searle & Co. | 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5354746A (en) * | 1993-06-01 | 1994-10-11 | G. D. Searle & Co. | Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5461047A (en) * | 1993-06-16 | 1995-10-24 | G. D. Searle & Co. | 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
| US5354747A (en) * | 1993-06-16 | 1994-10-11 | G. D. Searle & Co. | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
| US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5424424A (en) * | 1993-10-07 | 1995-06-13 | G. D. Searle & Co. | Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5488046A (en) * | 1993-11-03 | 1996-01-30 | G. D. Searle & Co. | Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5441950A (en) * | 1994-06-09 | 1995-08-15 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use |
| US5449675A (en) * | 1994-06-09 | 1995-09-12 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use |
| GB9514160D0 (en) * | 1994-07-25 | 1995-09-13 | Zeneca Ltd | Aromatic compounds |
| GB9417532D0 (en) * | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| US5698551A (en) * | 1995-04-07 | 1997-12-16 | Novo Nordisk A/S | Heterocyclic compounds |
| TW434240B (en) * | 1995-06-20 | 2001-05-16 | Zeneca Ltd | Aromatic compounds, preparation thereof and pharmaceutical composition comprising same |
| TW502026B (en) * | 1995-06-20 | 2002-09-11 | Zeneca Ltd | Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates |
| US5834468A (en) * | 1995-07-07 | 1998-11-10 | Zeneca Limited | Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists |
| CN1072650C (zh) * | 1996-06-07 | 2001-10-10 | 霍夫曼-拉罗奇有限公司 | 二苯并噁䓬和二苯并二噁䓬衍生物及其作为抗肿瘤药剂的用途 |
| JP2007531773A (ja) * | 2004-03-31 | 2007-11-08 | レキシコン・ジェネティクス・インコーポレーテッド | プロテインキナーゼ変調剤としての２−アミノメチルチアゾール−５−カルボキサミド |
| NZ578988A (en) | 2007-02-16 | 2012-03-30 | Ono Pharmaceutical Co | Therapeutic agent for urinary excretion disorder |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL127795C (fi) * | 1966-01-28 | |||
| US3452046A (en) * | 1966-04-29 | 1969-06-24 | Squibb & Sons Inc | Dibenzoazathiacycloalkane carboxamides and related oxa compounds |
| US3534019A (en) * | 1967-10-30 | 1970-10-13 | Searle & Co | Dibenzoxazepine - n - carboxylic acid hydrazides and related compounds |
| US3644346A (en) * | 1969-10-27 | 1972-02-22 | Searle & Co | Dibenzoxazepine semicarbazones |
| US3624104A (en) * | 1969-10-27 | 1971-11-30 | Searle & Co | Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides |
| US3917649A (en) * | 1971-03-23 | 1975-11-04 | Searle & Co | Dibenzoxazepine N-carboxylic acid hydrazides and derivatives |
| US3989719A (en) * | 1971-03-23 | 1976-11-02 | G. D. Searle & Co. | Dibenzoxazepine N-carboxylic acid hydrazides and derivatives |
| US3992375A (en) * | 1974-08-12 | 1976-11-16 | G. D. Searle & Co. | Dibenzoxazepine N-carboxylic acid hydrazines and derivatives |
| GB1522003A (en) * | 1975-10-17 | 1978-08-23 | Searle & Co | 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines |
| JPS6117663A (ja) * | 1984-07-03 | 1986-01-25 | 株式会社アイジー技術研究所 | 内、外壁改修構造 |
| US4728735A (en) * | 1984-10-15 | 1988-03-01 | Merck & Co., Inc. | 10,11-dihydro-dibenzo-[b,f][1,4]-thiazepin derivatives |
| US4614617A (en) * | 1985-02-25 | 1986-09-30 | G. D. Searle & Co. | Intermediates for 8-chlorodibenz[(b,f)][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides |
| US4559337A (en) * | 1985-02-25 | 1985-12-17 | G.D. Searle & Co. | 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides |
| US4559336A (en) * | 1985-02-25 | 1985-12-17 | G.D. Searle & Co. | 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides |
| US4704386A (en) * | 1985-08-29 | 1987-11-03 | G. D. Searle & Co. | 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides |
| JPH04211071A (ja) * | 1990-03-05 | 1992-08-03 | Hokuriku Seiyaku Co Ltd | 多環式化合物 |
-
1991
- 1991-09-27 GB GB919120640A patent/GB9120640D0/en active Pending
-
1992
- 1992-09-07 IL IL103082A patent/IL103082A0/xx unknown
- 1992-09-07 ZA ZA926783A patent/ZA926783B/xx unknown
- 1992-09-07 AU AU22179/92A patent/AU2217992A/en not_active Abandoned
- 1992-09-16 EP EP92308428A patent/EP0534667B1/en not_active Expired - Lifetime
- 1992-09-16 CA CA002078401A patent/CA2078401A1/en not_active Abandoned
- 1992-09-16 AT AT92308428T patent/ATE148700T1/de not_active IP Right Cessation
- 1992-09-16 DE DE69217312T patent/DE69217312T2/de not_active Expired - Fee Related
- 1992-09-21 HU HU9203002A patent/HU9203002D0/hu unknown
- 1992-09-23 CZ CS922920A patent/CZ292092A3/cs unknown
- 1992-09-23 TW TW081107497A patent/TW224972B/zh active
- 1992-09-25 GB GB929220242A patent/GB9220242D0/en active Pending
- 1992-09-25 KR KR1019920017470A patent/KR930006014A/ko not_active Application Discontinuation
- 1992-09-25 JP JP4256335A patent/JPH05230055A/ja active Pending
- 1992-09-25 NO NO92923736A patent/NO923736L/no unknown
- 1992-09-25 US US07/950,706 patent/US5317101A/en not_active Expired - Lifetime
- 1992-09-25 FI FI924300A patent/FI924300A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB9120640D0 (en) | 1991-11-06 |
| HU9203002D0 (en) | 1992-12-28 |
| FI924300A (fi) | 1993-03-28 |
| CZ292092A3 (en) | 1993-04-14 |
| US5317101A (en) | 1994-05-31 |
| ATE148700T1 (de) | 1997-02-15 |
| DE69217312T2 (de) | 1997-05-22 |
| EP0534667A1 (en) | 1993-03-31 |
| NO923736D0 (no) | 1992-09-25 |
| JPH05230055A (ja) | 1993-09-07 |
| KR930006014A (ko) | 1993-04-20 |
| AU2217992A (en) | 1993-04-01 |
| FI924300A0 (fi) | 1992-09-25 |
| ZA926783B (en) | 1993-03-29 |
| NO923736L (no) | 1993-03-29 |
| TW224972B (fi) | 1994-06-11 |
| CA2078401A1 (en) | 1993-03-28 |
| DE69217312D1 (de) | 1997-03-20 |
| EP0534667B1 (en) | 1997-02-05 |
| GB9220242D0 (en) | 1992-11-11 |
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