IL100800A - Medicinal preparations for the treatment and / or detection of malignancies in soft tissues containing ATDEH complexes - Google Patents

Medicinal preparations for the treatment and / or detection of malignancies in soft tissues containing ATDEH complexes

Info

Publication number
IL100800A
IL100800A IL10080092A IL10080092A IL100800A IL 100800 A IL100800 A IL 100800A IL 10080092 A IL10080092 A IL 10080092A IL 10080092 A IL10080092 A IL 10080092A IL 100800 A IL100800 A IL 100800A
Authority
IL
Israel
Prior art keywords
composition
metal
ligand
tumor
hedta
Prior art date
Application number
IL10080092A
Other languages
English (en)
Hebrew (he)
Other versions
IL100800A0 (en
Inventor
David A Wilson
R Keith Frank
Joseph R Garlich
Jaime Simon
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of IL100800A0 publication Critical patent/IL100800A0/xx
Publication of IL100800A publication Critical patent/IL100800A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
IL10080092A 1991-01-30 1992-01-29 Medicinal preparations for the treatment and / or detection of malignancies in soft tissues containing ATDEH complexes IL100800A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/648,663 US5308606A (en) 1991-01-30 1991-01-30 Method of treating and/or diagnosing soft tissue tumors

Publications (2)

Publication Number Publication Date
IL100800A0 IL100800A0 (en) 1992-09-06
IL100800A true IL100800A (en) 1996-10-31

Family

ID=24601702

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10080092A IL100800A (en) 1991-01-30 1992-01-29 Medicinal preparations for the treatment and / or detection of malignancies in soft tissues containing ATDEH complexes

Country Status (17)

Country Link
US (1) US5308606A (xx)
EP (1) EP0499098B1 (xx)
JP (1) JPH05505629A (xx)
KR (1) KR100219965B1 (xx)
AT (1) ATE216266T1 (xx)
AU (1) AU650944B2 (xx)
CA (1) CA2060332A1 (xx)
DE (1) DE69232554T2 (xx)
FI (1) FI924363A (xx)
IE (1) IE920311A1 (xx)
IL (1) IL100800A (xx)
MX (1) MX9200413A (xx)
NZ (1) NZ241463A (xx)
SG (1) SG45366A1 (xx)
TW (1) TW205509B (xx)
WO (1) WO1992013571A1 (xx)
ZA (1) ZA92663B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
MXPA02003771A (es) * 1999-10-15 2005-04-28 Mayo Foundation Conjugados de cobalamina, utiles como agentes para obtencion de imagen y como agentes anti-tumor.
US7591995B2 (en) * 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
EP1239887A1 (en) 1999-10-15 2002-09-18 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
TWI228512B (en) * 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
WO2003000010A2 (en) * 2001-06-20 2003-01-03 Mayo Foundation For Medical Education And Research Adenosyl-cobalamin fortified compositions
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
JP2005508332A (ja) * 2001-09-28 2005-03-31 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 薬剤を送達するための、輸送タンパク質とコンジュゲートコバラミンとの同時投与
KR100440725B1 (ko) * 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
WO2007008232A2 (en) * 2004-09-03 2007-01-18 Board Of Regents, The University Of Texas System Locoregional internal radionuclide ablation of abnormal tissues.
US7419654B2 (en) * 2004-10-08 2008-09-02 Mrinal K. Dewanjee Charge neutral complexes of paramagnetic metals as intracellular magnetic resonance imaging contrast agents
WO2006124870A1 (en) * 2005-05-17 2006-11-23 Cargill, Incorporated Granular lecithins, granular lysolecithins, process for their production and compositions containing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US421452A (en) * 1890-02-18 Island
US4898724A (en) * 1984-06-04 1990-02-06 The Dow Chemical Company Organis amine phosphonic acid complexes for the treatment of calcific tumors
EP0176288B1 (en) * 1984-09-21 1990-05-09 The Dow Chemical Company Aminocarboxylic acid complexes for the treatment of calcific tumors
US4897254A (en) * 1984-09-21 1990-01-30 The Dow Chemical Company Radioactive compositions for the treatment of calcific tumors
NZ222304A (en) * 1987-05-18 1990-10-26 Dow Chemical Co Suppression of bone marrow using samarium-153, gadolinium-159 or holmium-166 complexes

Also Published As

Publication number Publication date
IE920311A1 (en) 1992-07-29
CA2060332A1 (en) 1992-07-31
DE69232554T2 (de) 2002-08-08
FI924363A0 (fi) 1992-09-29
KR930700163A (ko) 1993-03-13
IL100800A0 (en) 1992-09-06
ATE216266T1 (de) 2002-05-15
NZ241463A (en) 2000-01-28
MX9200413A (es) 1992-08-01
WO1992013571A1 (en) 1992-08-20
AU650944B2 (en) 1994-07-07
FI924363A (fi) 1992-09-29
JPH05505629A (ja) 1993-08-19
US5308606A (en) 1994-05-03
KR100219965B1 (ko) 1999-09-01
EP0499098A2 (en) 1992-08-19
TW205509B (xx) 1993-05-11
SG45366A1 (en) 1998-01-16
DE69232554D1 (de) 2002-05-23
EP0499098B1 (en) 2002-04-17
EP0499098A3 (en) 1992-08-26
ZA92663B (en) 1993-07-30
AU1054392A (en) 1992-08-06

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees