IL100390A - תכשירי רוקחות המגבירים זמינות ביולוגית של פרובוקול והמורידים את השוני ברמה בנסיוב אצל חולים - Google Patents

תכשירי רוקחות המגבירים זמינות ביולוגית של פרובוקול והמורידים את השוני ברמה בנסיוב אצל חולים

Info

Publication number
IL100390A
IL100390A IL10039091A IL10039091A IL100390A IL 100390 A IL100390 A IL 100390A IL 10039091 A IL10039091 A IL 10039091A IL 10039091 A IL10039091 A IL 10039091A IL 100390 A IL100390 A IL 100390A
Authority
IL
Israel
Prior art keywords
probucol
fatty acids
pharmaceutical composition
bioavailability
captex
Prior art date
Application number
IL10039091A
Other languages
English (en)
Other versions
IL100390A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL100390A0 publication Critical patent/IL100390A0/xx
Publication of IL100390A publication Critical patent/IL100390A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL10039091A 1990-12-18 1991-12-16 תכשירי רוקחות המגבירים זמינות ביולוגית של פרובוקול והמורידים את השוני ברמה בנסיוב אצל חולים IL100390A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62954090A 1990-12-18 1990-12-18

Publications (2)

Publication Number Publication Date
IL100390A0 IL100390A0 (en) 1992-09-06
IL100390A true IL100390A (he) 1996-12-05

Family

ID=24523438

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10039091A IL100390A (he) 1990-12-18 1991-12-16 תכשירי רוקחות המגבירים זמינות ביולוגית של פרובוקול והמורידים את השוני ברמה בנסיוב אצל חולים

Country Status (17)

Country Link
EP (1) EP0563112B1 (he)
JP (1) JP3127998B2 (he)
KR (1) KR0177845B1 (he)
AT (1) ATE117200T1 (he)
AU (1) AU647563B2 (he)
CA (1) CA2097827C (he)
DE (1) DE69106892T2 (he)
DK (1) DK0563112T3 (he)
ES (1) ES2069987T3 (he)
FI (1) FI102457B1 (he)
GR (1) GR3015837T3 (he)
HU (1) HU210565B (he)
IE (1) IE65578B1 (he)
IL (1) IL100390A (he)
NO (1) NO303526B1 (he)
NZ (1) NZ240961A (he)
WO (1) WO1992010996A1 (he)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2517095A (en) * 1994-05-19 1995-12-18 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
JP2002532539A (ja) * 1998-12-18 2002-10-02 アボット・ラボラトリーズ 脂質調節剤を含む新規な製剤
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
US6838091B2 (en) 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
AU2571400A (en) * 1999-02-23 2000-09-14 Chugai Seiyaku Kabushiki Kaisha Seam soft capsule preparations containing dihydrobenzofuran derivative
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
WO2005037251A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
AU2019294705A1 (en) 2018-06-26 2021-01-21 Ribonova Inc Methods of treating mitochondrial dysfunction
WO2024006748A1 (en) * 2022-07-01 2024-01-04 Acrotech Biopharma Inc. Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof
CN116617179B (zh) * 2023-05-19 2024-03-29 齐鲁制药有限公司 一种普罗布考软胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862332A (en) * 1967-05-11 1975-01-21 Dow Chemical Co Method of lowering serum cholesterol
US4902513A (en) * 1987-07-31 1990-02-20 Jean Carvais Oral sustained release medicament

Also Published As

Publication number Publication date
AU647563B2 (en) 1994-03-24
KR930702965A (ko) 1993-11-29
NO932236D0 (no) 1993-06-17
HUT64218A (en) 1993-12-28
NZ240961A (en) 1994-03-25
FI932769A0 (fi) 1993-06-16
EP0563112A1 (en) 1993-10-06
IL100390A0 (en) 1992-09-06
JP3127998B2 (ja) 2001-01-29
IE914401A1 (en) 1992-07-01
GR3015837T3 (en) 1995-07-31
CA2097827A1 (en) 1992-06-19
KR0177845B1 (ko) 1999-03-20
HU9301769D0 (en) 1993-09-28
ATE117200T1 (de) 1995-02-15
NO932236L (no) 1993-06-17
HU210565B (en) 1995-05-29
NO303526B1 (no) 1998-07-27
EP0563112B1 (en) 1995-01-18
IE65578B1 (en) 1995-11-01
FI102457B (fi) 1998-12-15
FI102457B1 (fi) 1998-12-15
DK0563112T3 (da) 1995-04-10
JPH06503340A (ja) 1994-04-14
FI932769A (fi) 1993-06-16
AU9067891A (en) 1992-07-22
CA2097827C (en) 2002-07-23
DE69106892D1 (de) 1995-03-02
DE69106892T2 (de) 1995-05-18
WO1992010996A1 (en) 1992-07-09
ES2069987T3 (es) 1995-05-16

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