IE891251L - Method of purifying cross-linked hemoglobin - Google Patents

Method of purifying cross-linked hemoglobin

Info

Publication number
IE891251L
IE891251L IE125189A IE125189A IE891251L IE 891251 L IE891251 L IE 891251L IE 125189 A IE125189 A IE 125189A IE 125189 A IE125189 A IE 125189A IE 891251 L IE891251 L IE 891251L
Authority
IE
Ireland
Prior art keywords
linked hemoglobin
purifying cross
purifying
cross
hemoglobin
Prior art date
Application number
IE125189A
Other languages
English (en)
Original Assignee
Bradford John Georges
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bradford John Georges filed Critical Bradford John Georges
Publication of IE891251L publication Critical patent/IE891251L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IE125189A 1988-06-15 1989-04-18 Method of purifying cross-linked hemoglobin IE891251L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20734688A 1988-06-15 1988-06-15

Publications (1)

Publication Number Publication Date
IE891251L true IE891251L (en) 1989-12-15

Family

ID=22770150

Family Applications (1)

Application Number Title Priority Date Filing Date
IE125189A IE891251L (en) 1988-06-15 1989-04-18 Method of purifying cross-linked hemoglobin

Country Status (4)

Country Link
EP (1) EP0379534A4 (xx)
JP (1) JP2592973B2 (xx)
IE (1) IE891251L (xx)
WO (1) WO1989012456A1 (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955581A (en) * 1986-11-10 1999-09-21 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US5753616A (en) * 1986-11-10 1998-05-19 Biopure Corporation Method for producing a stable polymerized hemoglobin blood-substitute
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US6610832B1 (en) 1995-03-23 2003-08-26 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US6150507A (en) * 1995-03-23 2000-11-21 Biopure Corporation Method for producing a purified hemoglobin product
US5895810A (en) * 1995-03-23 1999-04-20 Biopure Corporation Stable polymerized hemoglobin and use thereof
US6288027B1 (en) 1995-03-23 2001-09-11 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US6271351B1 (en) 1995-03-23 2001-08-07 Biopure Corporation Method for preserving a hemoglobin blood substitute
EP1211261A3 (en) * 1995-03-23 2004-03-17 Biopure Corporation Stable polymerized hemoglobin blood-substitute
US5691452A (en) * 1995-03-23 1997-11-25 Biopure Corporation Method for preserving a hemoglobin blood substitute
US5741894A (en) * 1995-09-22 1998-04-21 Baxter International, Inc. Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
CA2236794A1 (en) * 1995-11-30 1997-06-05 Bruce A. Kerwin Method for control of functionality during cross-linking of hemoglobins
US6518010B2 (en) 2001-02-28 2003-02-11 Biopure Corporation Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
MXPA03009555A (es) 2001-04-18 2004-12-06 Northfield Lab Sistema de recipiente flexible para almacenamiento de soluciones de hemoglobina estabilizadas.
US7001715B2 (en) 2002-02-28 2006-02-21 Biopure Corporation Purification of red blood cells by separation and diafiltration
WO2008021577A2 (en) 2006-01-24 2008-02-21 The Board Of Trustees Of The University Of Illinois Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
US7932356B1 (en) * 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004407A1 (en) * 1984-03-23 1985-10-10 Baxter Travenol Laboratories, Inc. Virus risk-reduced hemoglobin and method for making same

Also Published As

Publication number Publication date
WO1989012456A1 (en) 1989-12-28
JPH03502580A (ja) 1991-06-13
EP0379534A1 (en) 1990-08-01
JP2592973B2 (ja) 1997-03-19
EP0379534A4 (en) 1991-03-13

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