IE830293L - Pyrimidones and intermediates. - Google Patents
Pyrimidones and intermediates.Info
- Publication number
- IE830293L IE830293L IE830293A IE29383A IE830293L IE 830293 L IE830293 L IE 830293L IE 830293 A IE830293 A IE 830293A IE 29383 A IE29383 A IE 29383A IE 830293 L IE830293 L IE 830293L
- Authority
- IE
- Ireland
- Prior art keywords
- lower alkyl
- diaminomethylene
- thiazolyl
- thio
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R<1> is H, lower alkyl, aralkyl, etc.; R<2> is lower alkyl; m and n are 1-3). EXAMPLE:2-[2-[[[2-[( Diaminomethylene )amino]-4-thiazolyl]methyl] thio]ethyl]-6-methylpyrimidine-4-one. USE:A suppressive agent for the secretion of acid in the stomach and an antiphlogistic. PROCESS:For example, an amidine derivative {e.g., 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propionamidine hydrochloride, etc.]} shown by the formula II is reacted with an acylacetic acid ester derivative (e.g., ethyl acetoacetate, etc.) shown by the formula III (R<5> is lower alkyl-, and, if necessary, in the presence of a base such as sodium methoxide, etc.
[JP58140088A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57022280A JPS58140088A (en) | 1982-02-15 | 1982-02-15 | Novel pyrimidine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
IE830293L true IE830293L (en) | 1983-08-15 |
Family
ID=12078341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE830293A IE830293L (en) | 1982-02-15 | 1983-02-14 | Pyrimidones and intermediates. |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS58140088A (en) |
KR (1) | KR840003633A (en) |
IE (1) | IE830293L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9745274B2 (en) | 2013-07-03 | 2017-08-29 | Shin Nippon Biomedical Laboratories, Ltd. | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor |
-
1982
- 1982-02-15 JP JP57022280A patent/JPS58140088A/en active Pending
-
1983
- 1983-02-14 KR KR1019830000582A patent/KR840003633A/en not_active Application Discontinuation
- 1983-02-14 IE IE830293A patent/IE830293L/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPS58140088A (en) | 1983-08-19 |
KR840003633A (en) | 1984-09-15 |
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