IE801537L - Phenylacetic acid derivatives. - Google Patents
Phenylacetic acid derivatives.Info
- Publication number
- IE801537L IE801537L IE801537A IE153780A IE801537L IE 801537 L IE801537 L IE 801537L IE 801537 A IE801537 A IE 801537A IE 153780 A IE153780 A IE 153780A IE 801537 L IE801537 L IE 801537L
- Authority
- IE
- Ireland
- Prior art keywords
- lower alkyl
- acid derivatives
- phenylacetic acid
- hydrogen atom
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel 2-amino-3- (alkylthiobenzoyl)phenylacetic acids, esters and metal salts have the formula: <IMAGE> wherein R represents a hydrogen atom or a lower alkyl group, R<1> represents hydrogen atom or a lower alkyl group or pharmaceutically acceptable metal cation, R<2> represents a hydrogen or a halogen atom or a lower alkyl or lower alkoxy group, and Am represents a primary amino (-NH2), methylamino or dimethylamino group. The compounds have anti- inflammatory activity; have effective analgesic activity, and inhibit blood platelet aggregation.
[GB2105708A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6302979A | 1979-08-01 | 1979-08-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE801537L true IE801537L (en) | 1981-02-01 |
IE50293B1 IE50293B1 (en) | 1986-03-19 |
Family
ID=22046443
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1537/80A IE50293B1 (en) | 1979-08-01 | 1980-07-24 | 2-amino-3-(alkylthiobenzoyl)phenylacetic acids |
Country Status (37)
Country | Link |
---|---|
JP (1) | JPS5629568A (en) |
KR (1) | KR840000605B1 (en) |
AR (1) | AR226855A1 (en) |
AT (1) | AT369648B (en) |
AU (1) | AU532247B2 (en) |
BE (1) | BE884556A (en) |
BR (1) | BR8004546A (en) |
CA (1) | CA1147746A (en) |
CH (1) | CH648295A5 (en) |
CS (1) | CS214716B2 (en) |
DE (1) | DE3026964A1 (en) |
DK (1) | DK330380A (en) |
EG (1) | EG14771A (en) |
ES (1) | ES493880A0 (en) |
FI (1) | FI74457C (en) |
FR (1) | FR2463124A1 (en) |
GB (2) | GB2055820B (en) |
GR (1) | GR69714B (en) |
HK (2) | HK37584A (en) |
HU (1) | HU181728B (en) |
IE (1) | IE50293B1 (en) |
IL (1) | IL60444A (en) |
IN (1) | IN151542B (en) |
IT (1) | IT1132273B (en) |
KE (2) | KE3368A (en) |
LU (1) | LU82672A1 (en) |
MX (1) | MX6175E (en) |
NL (1) | NL8004397A (en) |
NO (1) | NO150080C (en) |
NZ (1) | NZ194515A (en) |
PH (1) | PH18030A (en) |
PL (1) | PL127122B1 (en) |
PT (1) | PT71632B (en) |
SE (1) | SE447247B (en) |
SG (1) | SG19884G (en) |
YU (1) | YU41725B (en) |
ZA (1) | ZA804703B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0723478U (en) * | 1993-10-08 | 1995-05-02 | 有限会社伊藤商店 | Collar cover |
FR2711076B1 (en) * | 1993-10-13 | 1995-12-08 | Robatel Slpi | Waterproof and elastically deformable device for the deburring of the residual layer. |
WO2002070478A1 (en) | 2001-03-06 | 2002-09-12 | Astrazeneca Ab | Indolone derivatives having vascular-damaging activity |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH577461A5 (en) * | 1975-08-13 | 1976-07-15 | Robins Co Inc A H |
-
1980
- 1980-06-30 IL IL60444A patent/IL60444A/en unknown
- 1980-07-02 IN IN761/CAL/80A patent/IN151542B/en unknown
- 1980-07-11 AR AR281743A patent/AR226855A1/en active
- 1980-07-14 EG EG420/80A patent/EG14771A/en active
- 1980-07-14 GB GB8022968A patent/GB2055820B/en not_active Expired
- 1980-07-16 DE DE19803026964 patent/DE3026964A1/en active Granted
- 1980-07-18 FI FI802282A patent/FI74457C/en not_active IP Right Cessation
- 1980-07-19 GR GR62503A patent/GR69714B/el unknown
- 1980-07-22 BR BR8004546A patent/BR8004546A/en unknown
- 1980-07-23 YU YU1870/80A patent/YU41725B/en unknown
- 1980-07-23 PH PH24330A patent/PH18030A/en unknown
- 1980-07-24 IE IE1537/80A patent/IE50293B1/en unknown
- 1980-07-24 CA CA000356926A patent/CA1147746A/en not_active Expired
- 1980-07-28 AU AU60840/80A patent/AU532247B2/en not_active Ceased
- 1980-07-28 SE SE8005425A patent/SE447247B/en not_active IP Right Cessation
- 1980-07-29 JP JP10423980A patent/JPS5629568A/en active Granted
- 1980-07-30 CS CS805349A patent/CS214716B2/en unknown
- 1980-07-30 KR KR1019800003043A patent/KR840000605B1/en active
- 1980-07-30 BE BE0/201593A patent/BE884556A/en not_active IP Right Cessation
- 1980-07-30 LU LU82672A patent/LU82672A1/en unknown
- 1980-07-31 DK DK330380A patent/DK330380A/en unknown
- 1980-07-31 NO NO802306A patent/NO150080C/en unknown
- 1980-07-31 HU HU801919A patent/HU181728B/en not_active IP Right Cessation
- 1980-07-31 CH CH5844/80A patent/CH648295A5/en not_active IP Right Cessation
- 1980-07-31 ES ES493880A patent/ES493880A0/en active Granted
- 1980-07-31 FR FR8016939A patent/FR2463124A1/en active Granted
- 1980-07-31 MX MX808949U patent/MX6175E/en unknown
- 1980-07-31 NZ NZ194515A patent/NZ194515A/en unknown
- 1980-07-31 IT IT23840/80A patent/IT1132273B/en active
- 1980-07-31 PL PL1980225990A patent/PL127122B1/en unknown
- 1980-07-31 PT PT71632A patent/PT71632B/en unknown
- 1980-07-31 NL NL8004397A patent/NL8004397A/en not_active Application Discontinuation
- 1980-08-01 ZA ZA00804703A patent/ZA804703B/en unknown
- 1980-08-04 AT AT0403580A patent/AT369648B/en not_active IP Right Cessation
-
1982
- 1982-05-21 GB GB08214848A patent/GB2105708B/en not_active Expired
-
1984
- 1984-01-18 KE KE3368A patent/KE3368A/en unknown
- 1984-03-03 SG SG198/84A patent/SG19884G/en unknown
- 1984-03-30 KE KE3390A patent/KE3390A/en unknown
- 1984-05-03 HK HK375/84A patent/HK37584A/en unknown
- 1984-06-14 HK HK490/84A patent/HK49084A/en unknown
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