IE781147L - Alpha-acetylene amino acids. - Google Patents

Alpha-acetylene amino acids.

Info

Publication number
IE781147L
IE781147L IE781147A IE114778A IE781147L IE 781147 L IE781147 L IE 781147L IE 781147 A IE781147 A IE 781147A IE 114778 A IE114778 A IE 114778A IE 781147 L IE781147 L IE 781147L
Authority
IE
Ireland
Prior art keywords
hydrogen
carbonyl
carbon atoms
alkyl
alpha
Prior art date
Application number
IE781147A
Other versions
IE47082B1 (en
Original Assignee
Merrell Torande Et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Torande Et Cie filed Critical Merrell Torande Et Cie
Publication of IE781147L publication Critical patent/IE781147L/en
Publication of IE47082B1 publication Critical patent/IE47082B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutically useful compounds have the formula <IMAGE> wherein R1 is hydrogen, (C1-4alkyl) carbonyl, (C1-4alkoxy) carbonyl or CO-CHNH2-R27 wherein R27 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R is hydroxy, alkoxy of 1 to 8 carbon atoms, -NR7R8 wherein R7 and R8 are the same or different and are each hydrogen or C1-4alkyl, or NH-CHR9-COOH wherein R9 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and R2, R3, R4, R5 and R6 are certain combinations of hydrogen, methyl, ethyl, tert-butyl, chlorine, fluorine and OR10 wherein R10 is hydrogen, alkyl of 1 to 8 carbon atoms, (C1-6alkyl) carbonyl, benzoyl or phenyl (C1-6alkyl) carbonyl or R3 and R4 together are methylene dioxy. [GB2001060A]
IE1147/78A 1977-07-01 1978-06-06 -acetylenic amino acids IE47082B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81205877A 1977-07-01 1977-07-01

Publications (2)

Publication Number Publication Date
IE781147L true IE781147L (en) 1979-01-01
IE47082B1 IE47082B1 (en) 1983-12-14

Family

ID=25208370

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1147/78A IE47082B1 (en) 1977-07-01 1978-06-06 -acetylenic amino acids

Country Status (16)

Country Link
JP (1) JPS5414937A (en)
AU (1) AU521142B2 (en)
BE (1) BE868596A (en)
CA (1) CA1161451A (en)
CH (1) CH641150A5 (en)
DE (1) DE2827824A1 (en)
DK (1) DK299478A (en)
FR (1) FR2401133A1 (en)
GB (1) GB2001060B (en)
IE (1) IE47082B1 (en)
IL (1) IL54918A0 (en)
IT (1) IT1107978B (en)
NL (1) NL7807089A (en)
NZ (1) NZ187541A (en)
SE (1) SE7807359L (en)
ZA (1) ZA783354B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK309579A (en) * 1978-07-24 1980-02-22 Merck & Co Inc PROCESS FOR THE PREPARATION OF ALPHETHYNYLAMINO ACIDS AND ESTERS THEREOF
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
DE10261808A1 (en) * 2002-12-19 2004-07-08 Turicum Drug Development Ag Use of L-DOPA, its derivatives and medicaments containing these compounds for the prophylaxis of psychotic diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959356A (en) * 1975-03-18 1976-05-25 Richardson-Merrell Inc. Acetylene derivatives of amino acids
US4401676A (en) * 1977-06-01 1983-08-30 Merck & Co., Inc. Novel α-amino acids

Also Published As

Publication number Publication date
GB2001060A (en) 1979-01-24
FR2401133A1 (en) 1979-03-23
GB2001060B (en) 1982-02-24
NZ187541A (en) 1982-11-23
IT1107978B (en) 1985-12-02
IE47082B1 (en) 1983-12-14
DK299478A (en) 1979-01-02
JPS6334145B2 (en) 1988-07-08
IL54918A0 (en) 1978-08-31
AU521142B2 (en) 1982-03-18
CH641150A5 (en) 1984-02-15
JPS5414937A (en) 1979-02-03
DE2827824A1 (en) 1979-01-18
NL7807089A (en) 1979-01-03
ZA783354B (en) 1979-06-27
AU3732578A (en) 1980-01-03
CA1161451A (en) 1984-01-31
SE7807359L (en) 1979-01-02
FR2401133B1 (en) 1981-12-11
IT7850102A0 (en) 1978-06-29
BE868596A (en) 1978-10-16

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Legal Events

Date Code Title Description
SPCF Request for grant of supplementary protection certificate

Free format text: ERRATUM: SPC 62/93 ADDRESS OD APPLICANT TO READ: STRoNGNoSVoGEN 44, S-151 85 SoDERToLJE, SWEDEN. THE WORD "INGREDIENTS" TO READ "INGREDIENT".

MM4A Patent lapsed