IE780151L - Benzisoquinolines - Google Patents

Benzisoquinolines

Info

Publication number
IE780151L
IE780151L IE780151A IE15178A IE780151L IE 780151 L IE780151 L IE 780151L IE 780151 A IE780151 A IE 780151A IE 15178 A IE15178 A IE 15178A IE 780151 L IE780151 L IE 780151L
Authority
IE
Ireland
Prior art keywords
formula
compounds
benzisoquinolines
gb1596170a
depressing
Prior art date
Application number
IE780151A
Other versions
IE46381B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE780151L publication Critical patent/IE780151L/en
Publication of IE46381B1 publication Critical patent/IE46381B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Abstract

The invention relates to a process for preparing compounds of the formula I, <IMAGE> in which R1, R2 and R3 have the meaning given in the description, by the elimination of water from the corresponding octahydro-6-ol derivatives. The compounds of the formula I possess the properties of inhibiting aggression and depressing the central nervous system. [GB1596170A]
IE151/78A 1977-01-24 1978-01-23 1,2,3,4,4a,10b-hexahydro-benz(f)isoquinolines IE46381B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH82077A CH630902A5 (en) 1977-01-24 1977-01-24 Process for preparing novel derivatives of 1,2,3,4,4a,10b-hexahydrobenzo(f)isoquinoline.

Publications (2)

Publication Number Publication Date
IE780151L true IE780151L (en) 1978-07-24
IE46381B1 IE46381B1 (en) 1983-05-18

Family

ID=4195950

Family Applications (1)

Application Number Title Priority Date Filing Date
IE151/78A IE46381B1 (en) 1977-01-24 1978-01-23 1,2,3,4,4a,10b-hexahydro-benz(f)isoquinolines

Country Status (21)

Country Link
JP (1) JPS5392778A (en)
AT (1) AT367405B (en)
BE (1) BE863215A (en)
CA (1) CA1105468A (en)
CH (3) CH630902A5 (en)
DE (1) DE2801576A1 (en)
DK (1) DK19278A (en)
ES (2) ES466245A1 (en)
FI (1) FI780130A (en)
FR (1) FR2378015A1 (en)
GB (1) GB1596170A (en)
IE (1) IE46381B1 (en)
IL (1) IL53869A (en)
IT (1) IT7847687A0 (en)
NL (1) NL7800719A (en)
NZ (1) NZ186279A (en)
PH (1) PH14194A (en)
PT (1) PT67562B (en)
SE (1) SE7800452L (en)
SU (1) SU852172A3 (en)
ZA (1) ZA78430B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8302361D0 (en) * 1983-04-27 1983-04-27 Astra Laekemedel Ab NEW TRICYCLIC AMINES
US5294618A (en) * 1989-07-28 1994-03-15 Merck Sharp & Dohme Limited Octahydrobenzisoquinoline derivatives as antipsychotic agents
GB8917333D0 (en) * 1989-07-28 1989-09-13 Merck Sharp & Dohme Therapeutic agents
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics
CA2118920A1 (en) * 1991-10-24 1993-04-29 Arthur G. Romero Benzo-isoquinoline derivatives and analogs and their use in therapeutics
AT407636B (en) * 1999-07-09 2001-05-25 Martin Dr Kratzel Diels-Alder products of tetrahydropyridinedienes with naphthoquinones and their oxidation products, process for their preparation and their use for producing medicaments

Also Published As

Publication number Publication date
CH630904A5 (en) 1982-07-15
IE46381B1 (en) 1983-05-18
CA1105468A (en) 1981-07-21
NL7800719A (en) 1978-07-26
DE2801576A1 (en) 1978-07-27
ZA78430B (en) 1979-09-26
FR2378015B1 (en) 1980-08-22
ES466245A1 (en) 1980-12-16
ES475587A1 (en) 1980-02-16
PT67562B (en) 1980-11-03
IT7847687A0 (en) 1978-01-18
CH630902A5 (en) 1982-07-15
PT67562A (en) 1978-02-01
IL53869A (en) 1981-05-20
AT367405B (en) 1982-07-12
BE863215A (en) 1978-07-24
SE7800452L (en) 1978-07-25
DK19278A (en) 1978-07-25
FR2378015A1 (en) 1978-08-18
NZ186279A (en) 1980-05-27
PH14194A (en) 1981-03-26
JPS5392778A (en) 1978-08-15
IL53869A0 (en) 1978-04-30
GB1596170A (en) 1981-08-19
FI780130A (en) 1978-07-25
ATA45478A (en) 1981-11-15
AU3265478A (en) 1979-08-02
CH630903A5 (en) 1982-07-15
SU852172A3 (en) 1981-07-30

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