IE53315B1 - Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase - Google Patents

Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase

Info

Publication number
IE53315B1
IE53315B1 IE298181A IE298181A IE53315B1 IE 53315 B1 IE53315 B1 IE 53315B1 IE 298181 A IE298181 A IE 298181A IE 298181 A IE298181 A IE 298181A IE 53315 B1 IE53315 B1 IE 53315B1
Authority
IE
Ireland
Prior art keywords
loweralkyl
alkyl
hydrogen
alanine
substituted
Prior art date
Application number
IE298181A
Other languages
English (en)
Other versions
IE812981L (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IE812981L publication Critical patent/IE812981L/xx
Publication of IE53315B1 publication Critical patent/IE53315B1/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE298181A 1980-12-18 1981-12-17 Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase IE53315B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21762180A 1980-12-18 1980-12-18

Publications (2)

Publication Number Publication Date
IE812981L IE812981L (en) 1982-06-18
IE53315B1 true IE53315B1 (en) 1988-10-12

Family

ID=22811820

Family Applications (1)

Application Number Title Priority Date Filing Date
IE298181A IE53315B1 (en) 1980-12-18 1981-12-17 Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase

Country Status (2)

Country Link
JP (1) JPS5832851A (enrdf_load_stackoverflow)
IE (1) IE53315B1 (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57176946A (en) * 1981-02-17 1982-10-30 Merck & Co Inc Antihypertensive aza analogues of amino acid derivatives
GB8311286D0 (en) * 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives
ES2145929T3 (es) * 1994-11-04 2000-07-16 Santen Pharmaceutical Co Ltd Nuevo derivado de 1,3-dialquil-urea que tiene un grupo hidroxilo.
JO2967B1 (en) * 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPH0379339B2 (enrdf_load_stackoverflow) 1991-12-18
IE812981L (en) 1982-06-18
JPS5832851A (ja) 1983-02-25

Similar Documents

Publication Publication Date Title
EP0054862B1 (en) Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
KR850000303B1 (ko) 옥타히드로-1h-인돌-2-카복실산 치환 아실유도체의 제법
KR880001326B1 (ko) 1, 2, 3, 4-테트라하이드로이소퀴놀린-3-카복실산의 치환 아실 유도체
EP0088341B1 (en) Substituted acyl derivative of octahydro-1h-indole-2-carboxylic acid
FI81087C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-acyl-2-azabicyklo/3.3.0/-3-karboxylsyror.
KR850000847B1 (ko) 아미노산 유도체의 제조방법
US4128653A (en) Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives
US4714708A (en) Derivatives of cis, endo-2-azabicyclo[5.3.0]decane-3-carboxylic acid, and their use for treating hypertension
SK64993A3 (en) Hydroxamic acid derivatives, method of their preparation and medicaments with their content
JPS59141545A (ja) 光学的に活性な二環式イミノ−α−カルボン酸エステルのラセミ体の分割法
US4425355A (en) Substituted acyl derivatives of chair form of octahydro-1H-indole-2-carboxylic acids
US4474764A (en) 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same
JPH0559105B2 (enrdf_load_stackoverflow)
EP0818463B1 (en) Aspartyl dipeptide amide derivatives and sweeteners
IE53315B1 (en) Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
EP0058567B1 (en) Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters
US4490386A (en) Phosphate salts of 1-[2-[(1-alkoxycarbonyl-3-aralkyl)-amino]-1-oxoalkyl]octahydro-1H-indole-2-carboxylic acids, preparation of, and medical compositions thereof
IE56654B1 (en) A process for the resolution of racemates of optically active bicyclic imino-alpha-carboxylic esters,and the use of the compounds thus obtainable for the synthesis of carboxyalkyldipeptides
NZ201001A (en) Substituted dipeptide derivatives and method of preparation
KR890002173B1 (ko) 치환된 디펩티드 및 이의 제조방법
US4503043A (en) Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids
CA1304540C (en) Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
FI80051C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla substituerade dipeptider.
FI76560B (fi) Foerfarande foer framstaellning av farmaceutiskt anvaendbar 1-/2-/(1-karbetoxi-3-fenylpropyl)amino/-1- oxopropyl/-oktahydro-1h-indol-2-karboxylsyra.
US4442038A (en) Converting enzyme inhibitors

Legal Events

Date Code Title Description
MM4A Patent lapsed