IE47784B1 - 4-pyridone-3-carboxylic acid derivatives - Google Patents

4-pyridone-3-carboxylic acid derivatives

Info

Publication number
IE47784B1
IE47784B1 IE113/79A IE11379A IE47784B1 IE 47784 B1 IE47784 B1 IE 47784B1 IE 113/79 A IE113/79 A IE 113/79A IE 11379 A IE11379 A IE 11379A IE 47784 B1 IE47784 B1 IE 47784B1
Authority
IE
Ireland
Prior art keywords
oxo
acid
group
dihydronicotinic
ethyl
Prior art date
Application number
IE113/79A
Other languages
English (en)
Other versions
IE790113L (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH51278A external-priority patent/CH639073A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE790113L publication Critical patent/IE790113L/xx
Publication of IE47784B1 publication Critical patent/IE47784B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE113/79A 1978-01-18 1979-01-30 4-pyridone-3-carboxylic acid derivatives IE47784B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH51278A CH639073A5 (en) 1978-01-18 1978-01-18 4-Pyridone-3-carboxylic acid derivatives and their preparation
CH1173478 1978-11-15

Publications (2)

Publication Number Publication Date
IE790113L IE790113L (en) 1979-07-18
IE47784B1 true IE47784B1 (en) 1984-06-13

Family

ID=25684790

Family Applications (1)

Application Number Title Priority Date Filing Date
IE113/79A IE47784B1 (en) 1978-01-18 1979-01-30 4-pyridone-3-carboxylic acid derivatives

Country Status (25)

Country Link
US (2) US4521535A (US07655688-20100202-C00548.png)
EP (1) EP0003144B1 (US07655688-20100202-C00548.png)
JP (1) JPS54100382A (US07655688-20100202-C00548.png)
KR (1) KR820002111B1 (US07655688-20100202-C00548.png)
AR (1) AR223663A1 (US07655688-20100202-C00548.png)
AT (1) AT369731B (US07655688-20100202-C00548.png)
AU (1) AU521148B2 (US07655688-20100202-C00548.png)
CA (1) CA1110234A (US07655688-20100202-C00548.png)
DE (1) DE2901868A1 (US07655688-20100202-C00548.png)
DK (1) DK20279A (US07655688-20100202-C00548.png)
ES (1) ES476917A1 (US07655688-20100202-C00548.png)
FI (1) FI790103A (US07655688-20100202-C00548.png)
FR (1) FR2415103A1 (US07655688-20100202-C00548.png)
GB (1) GB2013190B (US07655688-20100202-C00548.png)
GR (1) GR73088B (US07655688-20100202-C00548.png)
HU (1) HU179487B (US07655688-20100202-C00548.png)
IE (1) IE47784B1 (US07655688-20100202-C00548.png)
IL (1) IL56421A (US07655688-20100202-C00548.png)
LU (1) LU80794A1 (US07655688-20100202-C00548.png)
MC (1) MC1239A1 (US07655688-20100202-C00548.png)
NL (1) NL7900264A (US07655688-20100202-C00548.png)
NO (1) NO152089C (US07655688-20100202-C00548.png)
NZ (1) NZ189379A (US07655688-20100202-C00548.png)
PT (1) PT69093A (US07655688-20100202-C00548.png)
SE (1) SE7900318L (US07655688-20100202-C00548.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1125762A (en) * 1979-07-13 1982-06-15 Alexander E. Wick Dihydronicotinic acid derivatives and process for the preparation thereof
ZA813029B (en) * 1980-05-12 1982-05-26 Rohm & Haas Novel substituted oxonicotinates,their use as plant growth regulators and plant growth regulating compositions containing them
US4964896A (en) * 1980-05-12 1990-10-23 Monsanto Company Certain-2,6-diphenyl-1,4-dihydro-4-oxo-nicotinates which are useful for inducing male sterility in cereal grain plants
US4936904A (en) * 1980-05-12 1990-06-26 Carlson Glenn R Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants
US4714492A (en) * 1980-05-12 1987-12-22 Rohm And Haas Company Certain 2-phenyl-4-oxo-nicotinates and their use for inducing male sterility in a cereal grain plant
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3338846A1 (de) * 1982-10-29 1984-05-03 Toyama Chemical Co. Ltd., Tokyo Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben
JPS5980665A (ja) * 1982-10-29 1984-05-10 Toyama Chem Co Ltd 4−オキソ−1,4−ジヒドロニコチン酸誘導体
GB8502424D0 (en) * 1985-01-31 1985-03-06 Pharis R P Promotion of flowering fruit trees
GB9317314D0 (en) * 1993-08-20 1993-10-06 Smithkline Beecham Corp Compounds
EP2149547A1 (en) * 2008-07-30 2010-02-03 LEK Pharmaceuticals D.D. Process for the synthesis of ezetimibe and intermediates useful therefor
WO2015099107A1 (ja) 2013-12-26 2015-07-02 塩野義製薬株式会社 含窒素6員環誘導体およびそれらを含有する医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907808A (en) * 1971-05-17 1975-09-23 Sterling Drug Inc 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
IN142614B (US07655688-20100202-C00548.png) * 1974-08-28 1977-08-06 Lilly Co Eli
CA1125762A (en) * 1979-07-13 1982-06-15 Alexander E. Wick Dihydronicotinic acid derivatives and process for the preparation thereof
DE3338846A1 (de) * 1982-10-29 1984-05-03 Toyama Chemical Co. Ltd., Tokyo Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben

Also Published As

Publication number Publication date
US4549022A (en) 1985-10-22
SE7900318L (sv) 1979-07-19
MC1239A1 (fr) 1979-10-26
AU4329679A (en) 1979-07-26
AT369731B (de) 1983-01-25
CA1110234A (en) 1981-10-06
HU179487B (en) 1982-10-28
NZ189379A (en) 1984-07-06
FR2415103B1 (US07655688-20100202-C00548.png) 1982-11-05
EP0003144A3 (en) 1979-08-08
GR73088B (US07655688-20100202-C00548.png) 1984-02-01
DK20279A (da) 1979-07-19
AU521148B2 (en) 1982-03-18
DE2901868A1 (de) 1979-07-19
FR2415103A1 (fr) 1979-08-17
IE790113L (en) 1979-07-18
EP0003144A2 (de) 1979-07-25
KR820002111B1 (ko) 1982-11-10
NO152089B (no) 1985-04-22
ES476917A1 (es) 1979-11-16
NO790165L (no) 1979-07-19
US4521535A (en) 1985-06-04
IL56421A0 (en) 1979-03-12
NO152089C (no) 1985-08-14
GB2013190A (en) 1979-08-08
PT69093A (en) 1979-02-01
NL7900264A (nl) 1979-07-20
FI790103A (fi) 1979-07-19
JPS54100382A (en) 1979-08-08
IL56421A (en) 1982-08-31
LU80794A1 (de) 1980-02-14
ATA35079A (de) 1982-06-15
GB2013190B (en) 1982-07-14
EP0003144B1 (de) 1981-08-05
AR223663A1 (es) 1981-09-15

Similar Documents

Publication Publication Date Title
US5019575A (en) Novel pyridazinone compounds, compositions thereof and method of use
US4613603A (en) Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in which they are present
IE47784B1 (en) 4-pyridone-3-carboxylic acid derivatives
US3984431A (en) Derivatives of pyrazole-5-acetic acid
DE2221546A1 (de) Verfahren zur Herstellung von neuen Imidazolderivaten
US4590270A (en) 2,4-diamino-[4-piperidinyl]pyrimidines useful as antibacterial agents, antimalarial agents, antitumors agents
US4021556A (en) Xanthine oxidase inhibitors
US4672063A (en) Antiallergic 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3-one compounds
DD265403A5 (de) Verfahren zum herstellen herzstimulierender chinolene
US4652565A (en) Piperazine derivatives, their production and pharmaceutical compositions containing them
US3824271A (en) 3-alkyl-3-(benzoyl)propionitriles
US3250761A (en) New sulfonamides
US4588725A (en) 2-piperazinyl-quinazoline derivatives and pharmaceutical compositions containing them
US3888901A (en) Process of preparing 3-alkyl-3-(benzoyl)propionitriles
IL35935A (en) 4,5-diphenyl imidazole derivatives and their production
US3842087A (en) 1,8-naphthyridine compounds
US4065617A (en) 2-(2,2,2,-Trifluoroethyl)-3,3a,4,5,6,7-hexahydro-2H-pyrazolo[4,3-c]pyridines
US3448107A (en) Tetrazole derivatives
US4213986A (en) Novel derivatives of imidazole and pharmaceutical compositions containing them and method of use
US3946010A (en) 3-Phenyl-2,5-dihydro-as-triazin-6 (1H)-ones
US3773777A (en) Hydrazones of pyrazolopyridine carboxylic acids and esters
US4066644A (en) Pyrazolo [1,5-a]pyrido[3,2-e]pyrimidine-7-carboxylic acid heterocyclic derivatives
US3133933A (en) Certain
US3761487A (en) Hydrazines of pyrazolopyridine carboxylic acids and esters
US4330543A (en) Imidazoazines and imidazodiazines