IE45889B1 - Biologically active tricyclic compounds and pharmaceutical compositions containing same - Google Patents

Biologically active tricyclic compounds and pharmaceutical compositions containing same

Info

Publication number
IE45889B1
IE45889B1 IE2103/77A IE210377A IE45889B1 IE 45889 B1 IE45889 B1 IE 45889B1 IE 2103/77 A IE2103/77 A IE 2103/77A IE 210377 A IE210377 A IE 210377A IE 45889 B1 IE45889 B1 IE 45889B1
Authority
IE
Ireland
Prior art keywords
alkyl
formula
compound
benzo
chloro
Prior art date
Application number
IE2103/77A
Other languages
English (en)
Other versions
IE45889L (en
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of IE45889L publication Critical patent/IE45889L/xx
Publication of IE45889B1 publication Critical patent/IE45889B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IE2103/77A 1976-10-27 1977-10-14 Biologically active tricyclic compounds and pharmaceutical compositions containing same IE45889B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB44675/76A GB1570613A (en) 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Publications (2)

Publication Number Publication Date
IE45889L IE45889L (en) 1978-04-27
IE45889B1 true IE45889B1 (en) 1982-12-29

Family

ID=10434306

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2103/77A IE45889B1 (en) 1976-10-27 1977-10-14 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Country Status (17)

Country Link
US (1) US4801753A (en, 2012)
JP (1) JPS5368767A (en, 2012)
AU (1) AU513607B2 (en, 2012)
BE (1) BE860141A (en, 2012)
CA (1) CA1081704A (en, 2012)
DE (1) DE2747987A1 (en, 2012)
DK (1) DK147280C (en, 2012)
ES (1) ES463570A1 (en, 2012)
FI (1) FI64574C (en, 2012)
FR (1) FR2369245A1 (en, 2012)
GB (1) GB1570613A (en, 2012)
HU (1) HU178984B (en, 2012)
IE (1) IE45889B1 (en, 2012)
LU (1) LU78392A1 (en, 2012)
NL (1) NL7711777A (en, 2012)
SE (1) SE425779B (en, 2012)
ZA (1) ZA776142B (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
US5089506A (en) * 1990-04-30 1992-02-18 G. D. Searle & Co. Ethanobicyclic amine derivatives for cns disorders
US5215992A (en) * 1990-04-30 1993-06-01 G. D. Searle & Co. Ethanobicyclic amine derivatives for CNS disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159677A (en) * 1960-04-12 1964-12-01 Parke Davis & Co Fluorenamines and process for preparation thereof
US3836670A (en) * 1971-11-19 1974-09-17 American Home Prod Benzobicycloalkane amines for inducing analgesia
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4313896A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Aryloxyphenylpropylamines
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB1504694A (en) * 1974-04-08 1978-03-22 Akzo Nv Benzo-bicyclononene derivatives
GB1549172A (en) * 1975-04-29 1979-08-01 Akzonv Benzobicyclononene derivatives

Also Published As

Publication number Publication date
ZA776142B (en) 1978-06-28
DK474977A (da) 1978-04-28
FI64574B (fi) 1983-08-31
JPS6126773B2 (en, 2012) 1986-06-21
FI64574C (fi) 1983-12-12
DK147280C (da) 1984-12-03
AU2998377A (en) 1979-05-03
BE860141A (fr) 1978-04-26
DK147280B (da) 1984-06-04
ES463570A1 (es) 1979-09-16
DE2747987C2 (en, 2012) 1988-02-25
FR2369245B1 (en, 2012) 1980-09-26
SE7712040L (sv) 1978-04-28
FI773193A7 (fi) 1978-04-28
AU513607B2 (en) 1980-12-11
DE2747987A1 (de) 1978-05-03
US4801753A (en) 1989-01-31
GB1570613A (en) 1980-07-02
HU178984B (en) 1982-07-28
LU78392A1 (en, 2012) 1978-01-26
SE425779B (sv) 1982-11-08
JPS5368767A (en) 1978-06-19
IE45889L (en) 1978-04-27
CA1081704A (en) 1980-07-15
NL7711777A (nl) 1978-05-02
FR2369245A1 (fr) 1978-05-26

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