IE44133L - Process for preparing 2-cephem compounds. - Google Patents

Process for preparing 2-cephem compounds.

Info

Publication number
IE44133L
IE44133L IE762598A IE259876A IE44133L IE 44133 L IE44133 L IE 44133L IE 762598 A IE762598 A IE 762598A IE 259876 A IE259876 A IE 259876A IE 44133 L IE44133 L IE 44133L
Authority
IE
Ireland
Prior art keywords
preparing
cephem compounds
acyloxymethyl
delta
formula
Prior art date
Application number
IE762598A
Other versions
IE44133B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/650,585 external-priority patent/US4031082A/en
Priority claimed from US05/650,583 external-priority patent/US4029651A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE44133L publication Critical patent/IE44133L/en
Publication of IE44133B1 publication Critical patent/IE44133B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

3-Acyloxymethyl-delta<2>-cephem compounds of the formula (I) <IMAGE> in which the substituents are defined in Claim 1, are obtained by reacting a 3-exomethylenecepham sulphoxide with a mixture of an acyl compound and of an appropriate anhydride at a temperature from 70 to 140 DEG C. The 3-acyloxymethyl-delta<2>-cephem esters of the formula I are generally valuable intermediates in the preparation of cephalosporins with antibiotic activity. [GB1566526A]
IE2598/76A 1976-01-19 1976-11-26 Process for preparing 2-cephem compounds IE44133B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/650,585 US4031082A (en) 1976-01-19 1976-01-19 Process for preparing 3-acycloxymethyl-2-cephem compounds
US05/650,583 US4029651A (en) 1976-01-19 1976-01-19 Process for preparing 3-acyloxymethyl-2-cephem compounds

Publications (2)

Publication Number Publication Date
IE44133L true IE44133L (en) 1977-07-19
IE44133B1 IE44133B1 (en) 1981-08-26

Family

ID=27095900

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2598/76A IE44133B1 (en) 1976-01-19 1976-11-26 Process for preparing 2-cephem compounds

Country Status (25)

Country Link
JP (1) JPS5289698A (en)
AR (1) AR213426A1 (en)
AT (1) AT348121B (en)
AU (1) AU503930B2 (en)
BG (1) BG30473A3 (en)
CH (1) CH628059A5 (en)
CS (1) CS192474B2 (en)
DD (1) DD128734A5 (en)
DE (1) DE2656144C2 (en)
DK (1) DK17977A (en)
FR (1) FR2338280A1 (en)
GB (1) GB1566526A (en)
GR (1) GR65892B (en)
HU (1) HU173592B (en)
IE (1) IE44133B1 (en)
IL (1) IL51021A (en)
MX (1) MX3766E (en)
NL (1) NL7700500A (en)
NZ (1) NZ182737A (en)
PL (1) PL104370B1 (en)
PT (1) PT66007B (en)
RO (1) RO69710A (en)
SE (1) SE433849B (en)
SU (1) SU703023A3 (en)
YU (1) YU8677A (en)

Also Published As

Publication number Publication date
IL51021A (en) 1979-09-30
NZ182737A (en) 1978-04-28
AR213426A1 (en) 1979-01-31
PL104370B1 (en) 1979-08-31
GR65892B (en) 1980-12-01
IE44133B1 (en) 1981-08-26
JPS6120557B2 (en) 1986-05-22
SE7700077L (en) 1977-07-20
FR2338280B1 (en) 1979-09-28
SE433849B (en) 1984-06-18
DE2656144A1 (en) 1977-07-21
HU173592B (en) 1979-06-28
CH628059A5 (en) 1982-02-15
DD128734A5 (en) 1977-12-07
AU503930B2 (en) 1979-09-27
DK17977A (en) 1977-07-20
RO69710A (en) 1980-07-15
YU8677A (en) 1982-06-30
AU2023876A (en) 1978-06-08
JPS5289698A (en) 1977-07-27
NL7700500A (en) 1977-07-21
GB1566526A (en) 1980-04-30
PT66007B (en) 1978-06-16
DE2656144C2 (en) 1985-08-29
IL51021A0 (en) 1977-01-31
CS192474B2 (en) 1979-08-31
MX3766E (en) 1981-06-25
FR2338280A1 (en) 1977-08-12
AT348121B (en) 1979-01-25
ATA28177A (en) 1978-06-15
SU703023A3 (en) 1979-12-05
PT66007A (en) 1977-01-01
BG30473A3 (en) 1981-06-15
PL195386A1 (en) 1978-02-27

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