IE43083L - Sustained release formulations - Google Patents

Sustained release formulations

Info

Publication number
IE43083L
IE43083L IE760508A IE50876A IE43083L IE 43083 L IE43083 L IE 43083L IE 760508 A IE760508 A IE 760508A IE 50876 A IE50876 A IE 50876A IE 43083 L IE43083 L IE 43083L
Authority
IE
Ireland
Prior art keywords
sustained release
mixture
weight
gastric juice
formulation
Prior art date
Application number
IE760508A
Other versions
IE43083B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from KR7600645A external-priority patent/KR800001387B1/en
Publication of IE43083L publication Critical patent/IE43083L/en
Publication of IE43083B1 publication Critical patent/IE43083B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

Landscapes

  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Solid pharmaceutical formulations are described which have a sustained release effect and which are buoyant in gastric juice. The formulation is present in the form of a homogeneous mixture. This mixture contains at least one therapeutic active compound, up to 80% by weight of therapeutically inert, pharmaceutically acceptable auxiliary substances, up to 60% by weight of a fatty material having a specific weight less than 1 and such a proportion of a hydrocolloid or of a mixture of hydrocolloids, incorporated into the formulation essentially in the dry form, that, after contact with the gastric juice, a layer which is impermeable to water is generated on the surface of this homogeneous mixture. [GB1546448A]
IE508/76A 1975-03-17 1976-03-11 Substained-release formulations IE43083B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55910775A 1975-03-17 1975-03-17
US65800376A 1976-02-13 1976-02-13
KR7600645A KR800001387B1 (en) 1975-03-17 1976-03-16 Process for preparing sustained release formulation

Publications (2)

Publication Number Publication Date
IE43083L true IE43083L (en) 1976-09-17
IE43083B1 IE43083B1 (en) 1980-12-17

Family

ID=27348140

Family Applications (1)

Application Number Title Priority Date Filing Date
IE508/76A IE43083B1 (en) 1975-03-17 1976-03-11 Substained-release formulations

Country Status (21)

Country Link
JP (1) JPS51115910A (en)
AR (1) AR222624A1 (en)
AT (1) AT353415B (en)
AU (1) AU505355B2 (en)
CA (1) CA1073358A (en)
CH (1) CH630257A5 (en)
DD (1) DD124102A5 (en)
DE (1) DE2611041A1 (en)
DK (1) DK148344C (en)
ES (1) ES446075A1 (en)
FR (1) FR2304354A1 (en)
GB (1) GB1546448A (en)
GR (1) GR60341B (en)
IE (1) IE43083B1 (en)
LU (1) LU74558A1 (en)
MC (1) MC1101A1 (en)
NL (1) NL190313C (en)
NZ (1) NZ180321A (en)
PH (1) PH14927A (en)
PT (1) PT64907B (en)
SE (1) SE433804B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ197543A (en) * 1980-07-02 1984-12-14 Commw Scient Ind Res Org Controlled release compositions for inclusion in intraruminal devices
CH649215A5 (en) * 1981-04-29 1985-05-15 Hoffmann La Roche PHARMACEUTICAL PREPARATIONS.
CH652025A5 (en) * 1981-09-14 1985-10-31 Hoffmann La Roche Pharmaceutical preparation.
US4421736A (en) * 1982-05-20 1983-12-20 Merrel Dow Pharmaceuticals Inc. Sustained release diethylpropion compositions
GB2154874B (en) * 1984-02-29 1987-11-04 Sandoz Ltd Bromoscriptine compositions
CH666406A5 (en) * 1984-02-29 1988-07-29 Sandoz Ag METHOD FOR PRODUCING microcapsules BROMOKRIPTINMESYLAT AS PHARMACOLOGICAL ACTIVE INCLUDED.
AU4064285A (en) * 1984-03-21 1985-10-11 American Home Products Corporation Sustained release pharmaceutical capsules
JPS6143108A (en) * 1984-08-03 1986-03-01 Nippon Shinyaku Co Ltd Medicinal drug and its preparation
NL8600161A (en) * 1985-02-05 1986-09-01 Sandoz Ag PHARMACEUTICAL PREPARATIONS CONTAINING 9,10-DIHYDROGOTALKALOIDS.
GB8524135D0 (en) * 1985-10-01 1985-11-06 Sandoz Ltd Darodipine compositions
NL194822C (en) * 1985-10-01 2003-04-03 Novartis Ag Preparation for oral administration with controlled release and method for its preparation.
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US4814178A (en) * 1987-07-01 1989-03-21 Sanford Bolton Floating sustained release therapeutic compositions
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
IE64128B1 (en) * 1990-02-26 1995-07-12 Byrne Rynne Holdings Ltd A pharmaceutical composition
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
SK282071B6 (en) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Water-dispersible tablet and its preparation method
JP2626248B2 (en) * 1991-04-08 1997-07-02 日本新薬株式会社 Capsule
ATE173159T1 (en) * 1992-03-25 1998-11-15 Depomed Systems Inc ORAL MEDICINAL DOSAGE FORMS BASED ON HYDROXYETHYL CELLULOSE WITH DELAYED RELEASE
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US5888540A (en) * 1993-10-29 1999-03-30 Sugden; Keith Pharmaceutical products
CN1133558A (en) * 1993-10-29 1996-10-16 雷克特和科尔曼产品有限公司 Gelatin capsule fill able to foam
WO1995011667A1 (en) * 1993-10-29 1995-05-04 R.P. Scherer Corporation Gelatin capsule fill able to foam
WO1995031186A1 (en) * 1994-05-13 1995-11-23 Smithkline Beecham Corporation Method and composition for increasing calcium uptake
JPH10509981A (en) * 1994-12-01 1998-09-29 サイバス ファーマシューティカル，インコーポレイティド Sustained drug delivery using powdered hydrocolloid rubber obtainable from higher plants
FR2820319B3 (en) * 2001-02-08 2003-12-05 Ellipse Pharmaceuticals PROCESS FOR PRODUCING A FLOATING TABLET INCLUDING ALFUZOSINE AND TABLET OBTAINED
FR2820318B1 (en) * 2001-02-08 2005-12-23 Ellipse Pharmaceuticals METHOD FOR MANUFACTURING A FLOATING COMPRESSOR INCLUDING AN ACTIVE INGREDIENT AND A COMPRESS OBTAINED
EP1245227A1 (en) * 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
FR2874325B1 (en) * 2004-08-19 2006-10-20 Sanofi Synthelabo PHARMACEUTICAL COMPOSITION IN THE FORM OF A GASTRIC RESISTANCE COMPRESSOR CONTAINING ALFUZOSIN

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1059624B (en) * 1954-11-11 1959-06-18 Dr Knut Jacobus Sundman Process for the production of medicaments dispersed in a carrier substance in dosed form
JPS5512411B2 (en) * 1974-03-12 1980-04-02
DE2439538C3 (en) * 1974-08-17 1980-07-17 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Process for the manufacture of orally administered drugs with delayed release of action

Also Published As

Publication number Publication date
AR222624A1 (en) 1981-06-15
DD124102A5 (en) 1977-02-02
DK148344B (en) 1985-06-17
DK113676A (en) 1976-09-18
FR2304354A1 (en) 1976-10-15
DK148344C (en) 1985-11-04
FR2304354B1 (en) 1979-04-27
JPS638084B2 (en) 1988-02-19
PT64907B (en) 1978-03-24
AU505355B2 (en) 1979-11-15
AU1204976A (en) 1977-09-22
JPS51115910A (en) 1976-10-13
CA1073358A (en) 1980-03-11
SE7603325L (en) 1976-09-18
NL190313B (en) 1993-08-16
GB1546448A (en) 1979-05-23
GR60341B (en) 1978-05-17
AT353415B (en) 1979-11-12
ATA192276A (en) 1979-04-15
NZ180321A (en) 1978-06-20
DE2611041A1 (en) 1976-10-14
ES446075A1 (en) 1977-09-16
MC1101A1 (en) 1977-02-04
NL190313C (en) 1994-01-17
NL7602776A (en) 1976-09-21
LU74558A1 (en) 1977-09-27
DE2611041C2 (en) 1988-06-09
IE43083B1 (en) 1980-12-17
SE433804B (en) 1984-06-18
PH14927A (en) 1982-01-29
CH630257A5 (en) 1982-06-15
PT64907A (en) 1976-04-01

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