IE41112B1 - Furyl compounds - Google Patents

Furyl compounds

Info

Publication number
IE41112B1
IE41112B1 IE863/75A IE86375A IE41112B1 IE 41112 B1 IE41112 B1 IE 41112B1 IE 863/75 A IE863/75 A IE 863/75A IE 86375 A IE86375 A IE 86375A IE 41112 B1 IE41112 B1 IE 41112B1
Authority
IE
Ireland
Prior art keywords
compounds
methyl
carbon atoms
formula
group
Prior art date
Application number
IE863/75A
Other versions
IE41112L (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/555,309 external-priority patent/US4001425A/en
Priority claimed from US05/555,306 external-priority patent/US3969370A/en
Application filed by Du Pont filed Critical Du Pont
Publication of IE41112L publication Critical patent/IE41112L/en
Publication of IE41112B1 publication Critical patent/IE41112B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Novel furyl urea compounds which are valuable medicaments for the treatment of hypertension in warm-blooded animals are prepared. Some of these compounds furthermore exert a retarding action on plant growth. The furyl compounds have the formula (I) <IMAGE> wherein R1, R2 and R3 denote an alkyl group having 1 to 4 carbon atoms or an alkenyl group having 2 to 4 carbon atoms, with the proviso that the total number of carbon atoms of R1+R2+R3 does not exceed six and that not more than one R1, R2 or R3 denotes alkynyl. Two of the radicals R1, R2 and R3 can together form the supplementary moiety of a cycloalkyl or cycloalkenyl group. X represents a methylene group which is optionally substituted by methyl, ethyl, propyl or butyl and R4 is hydrogen or methyl, but X represents methylene if R4 is methyl. The invention also includes the sodium, potassium and calcium salts of those compounds of the formula (I) in which X is a methylene group optionally substituted by methyl or ethyl. The furylureas are prepared by reacting compounds of the formula (II) <IMAGE> with appropriate 2,4-furanediones. [GB1463043A]
IE863/75A 1974-04-17 1975-04-17 Furyl compounds IE41112B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46169874A 1974-04-17 1974-04-17
US46170074A 1974-04-17 1974-04-17
US05/555,309 US4001425A (en) 1974-04-17 1975-03-11 Methods of treating hypertension and pharmaceutical compositions comprising 1-tertiary-alkyl-3-(substituted furyl)ureas as antihypertensive agents
US05/555,306 US3969370A (en) 1974-04-17 1975-03-11 1-Tertiary-alkyl-3-(substituted furyl)ureas as antihypertensive agents

Publications (2)

Publication Number Publication Date
IE41112L IE41112L (en) 1975-10-17
IE41112B1 true IE41112B1 (en) 1979-10-24

Family

ID=27504072

Family Applications (1)

Application Number Title Priority Date Filing Date
IE863/75A IE41112B1 (en) 1974-04-17 1975-04-17 Furyl compounds

Country Status (16)

Country Link
JP (1) JPS50148352A (en)
AR (1) AR206143A1 (en)
CH (2) CH614202A5 (en)
DD (1) DD119784A5 (en)
DE (1) DE2516555A1 (en)
DK (1) DK164075A (en)
ES (1) ES436649A1 (en)
FI (1) FI751129A (en)
FR (1) FR2267771B1 (en)
GB (1) GB1463043A (en)
IE (1) IE41112B1 (en)
LU (1) LU72307A1 (en)
NO (1) NO144070C (en)
SE (1) SE418613B (en)
SU (1) SU564811A3 (en)
YU (1) YU96275A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6016989A (en) * 1983-07-06 1985-01-28 Shionogi & Co Ltd Oxo-saturated heterocyclic carbon amide cephem compound
CO4970714A1 (en) * 1997-09-05 2000-11-07 Boehringer Mannheim Gmbh UREID AND THIOUREID DERIVATIVES OF 4-AMINO-2 (5H) -FURANONAS AND 4-AMINO-2 (5H) THIOPHENONAS AS ANTITUMORAL AGENTS

Also Published As

Publication number Publication date
DD119784A5 (en) 1976-05-12
SU564811A3 (en) 1977-07-05
CH615672A5 (en) 1980-02-15
NO144070B (en) 1981-03-09
CH614202A5 (en) 1979-11-15
NO144070C (en) 1981-06-17
SE7503524L (en) 1975-10-20
AR206143A1 (en) 1976-06-30
DE2516555A1 (en) 1975-10-30
GB1463043A (en) 1977-02-02
SE418613B (en) 1981-06-15
NO751352L (en) 1975-10-20
FI751129A (en) 1975-10-18
LU72307A1 (en) 1976-03-17
FR2267771A1 (en) 1975-11-14
JPS50148352A (en) 1975-11-27
DK164075A (en) 1975-10-18
FR2267771B1 (en) 1978-08-18
YU96275A (en) 1983-04-27
IE41112L (en) 1975-10-17
AU8013675A (en) 1976-10-21
ES436649A1 (en) 1977-05-01

Similar Documents

Publication Publication Date Title
ES8401466A1 (en) Compounds, process for their preparation and their use as pharmaceutical preparations.
ES469567A1 (en) Organic compounds
ES8405398A1 (en) Diazabicyclo(3.3.1)nonanes.
ES8103070A1 (en) Guanidinothiazole compounds, and medical compositions containing them
ES8402268A1 (en) Indole-5-acetamides for treatment of migraine
ZA818934B (en) Trisubstituted pyrimido pyrimidines,processes for their preparation,and pharmaceutical compositions thereof
ES441591A1 (en) 11-Aminoalkyl-pyridobenzodiazepinones and salts thereof
ES8100284A1 (en) Furan compounds
IE41112B1 (en) Furyl compounds
SE7602123L (en) NEW SUBSTITUTED PIPERAZINYLIMINORIFAMYCINS AND WAYS TO PREPARE THE SAME
ES438234A1 (en) Oxacyclohexane derivatives
ES468658A1 (en) 4-alkylthio-2-trifluoromethyl-alkanesulphonalides and derivatives thereof
ES466815A1 (en) 1,3-Disubstituted (2-thio)ureas
SE7902867L (en) ANTI-COMPLEMENTARY MEANS
ES8300778A1 (en) Process for preparation of cytostatic compounds
ES8401761A1 (en) 1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof.
ES436126A1 (en) 5-Amino or substituted amino-7-phenyl or substituted phenyl-2,3-dihydro-1H-1,4-diazepines
ES471267A1 (en) Lower alkyl 2-tri-(lower)alkylsilylacetylene-N-carbethoxyglycinates and process for using same
JPS52100470A (en) Synthesis of hydantoin derivatives
GB1236078A (en) Substituted azetidinols
ES8103740A1 (en) Piperazine methane imine derivatives, methods for their preparation and their therapeutical use.
ES8105300A1 (en) Acylaminobenzoic acid derivatives
ES8102110A1 (en) 1,2,3-Thiadiazol-5-yl-thioglycolic acid, its derivatives and process for their preparation.
DE3160968D1 (en) Cardenolide-bis-digitoxoside derivatives, process for their preparation and their utilization as medicines
ES481603A1 (en) Prostaglandin analogue imidazole derivatives, a process for their preparation and a pharmaceutical composition containing them.