GB1463043A - Furyl compounds - Google Patents
Furyl compoundsInfo
- Publication number
- GB1463043A GB1463043A GB1567375A GB1567375A GB1463043A GB 1463043 A GB1463043 A GB 1463043A GB 1567375 A GB1567375 A GB 1567375A GB 1567375 A GB1567375 A GB 1567375A GB 1463043 A GB1463043 A GB 1463043A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- methyl
- carbon atoms
- formula
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Novel furyl urea compounds which are valuable medicaments for the treatment of hypertension in warm-blooded animals are prepared. Some of these compounds furthermore exert a retarding action on plant growth. The furyl compounds have the formula (I) <IMAGE> wherein R1, R2 and R3 denote an alkyl group having 1 to 4 carbon atoms or an alkenyl group having 2 to 4 carbon atoms, with the proviso that the total number of carbon atoms of R1+R2+R3 does not exceed six and that not more than one R1, R2 or R3 denotes alkynyl. Two of the radicals R1, R2 and R3 can together form the supplementary moiety of a cycloalkyl or cycloalkenyl group. X represents a methylene group which is optionally substituted by methyl, ethyl, propyl or butyl and R4 is hydrogen or methyl, but X represents methylene if R4 is methyl. The invention also includes the sodium, potassium and calcium salts of those compounds of the formula (I) in which X is a methylene group optionally substituted by methyl or ethyl. The furylureas are prepared by reacting compounds of the formula (II) <IMAGE> with appropriate 2,4-furanediones.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46169874A | 1974-04-17 | 1974-04-17 | |
US46170074A | 1974-04-17 | 1974-04-17 | |
US05/555,309 US4001425A (en) | 1974-04-17 | 1975-03-11 | Methods of treating hypertension and pharmaceutical compositions comprising 1-tertiary-alkyl-3-(substituted furyl)ureas as antihypertensive agents |
US05/555,306 US3969370A (en) | 1974-04-17 | 1975-03-11 | 1-Tertiary-alkyl-3-(substituted furyl)ureas as antihypertensive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1463043A true GB1463043A (en) | 1977-02-02 |
Family
ID=27504072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1567375A Expired GB1463043A (en) | 1974-04-17 | 1975-04-16 | Furyl compounds |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS50148352A (en) |
AR (1) | AR206143A1 (en) |
CH (2) | CH614202A5 (en) |
DD (1) | DD119784A5 (en) |
DE (1) | DE2516555A1 (en) |
DK (1) | DK164075A (en) |
ES (1) | ES436649A1 (en) |
FI (1) | FI751129A (en) |
FR (1) | FR2267771B1 (en) |
GB (1) | GB1463043A (en) |
IE (1) | IE41112B1 (en) |
LU (1) | LU72307A1 (en) |
NO (1) | NO144070C (en) |
SE (1) | SE418613B (en) |
SU (1) | SU564811A3 (en) |
YU (1) | YU96275A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2143234A (en) * | 1983-07-06 | 1985-02-06 | Shinogi Seiyaku Kabushiki Kais | (oxoheterocyclic carbonamido) cephem carboxylic acid derivatives |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO4970714A1 (en) * | 1997-09-05 | 2000-11-07 | Boehringer Mannheim Gmbh | UREID AND THIOUREID DERIVATIVES OF 4-AMINO-2 (5H) -FURANONAS AND 4-AMINO-2 (5H) THIOPHENONAS AS ANTITUMORAL AGENTS |
-
1975
- 1975-01-01 AR AR258394A patent/AR206143A1/en active
- 1975-03-26 SE SE7503524A patent/SE418613B/en unknown
- 1975-04-10 DD DD185483A patent/DD119784A5/xx unknown
- 1975-04-16 FI FI751129A patent/FI751129A/fi not_active Application Discontinuation
- 1975-04-16 YU YU00962/75A patent/YU96275A/en unknown
- 1975-04-16 FR FR7511795A patent/FR2267771B1/fr not_active Expired
- 1975-04-16 ES ES436649A patent/ES436649A1/en not_active Expired
- 1975-04-16 SU SU7502123082A patent/SU564811A3/en active
- 1975-04-16 DE DE19752516555 patent/DE2516555A1/en not_active Withdrawn
- 1975-04-16 NO NO751352A patent/NO144070C/en unknown
- 1975-04-16 DK DK164075A patent/DK164075A/en not_active IP Right Cessation
- 1975-04-16 GB GB1567375A patent/GB1463043A/en not_active Expired
- 1975-04-17 JP JP50045922A patent/JPS50148352A/ja active Pending
- 1975-04-17 CH CH494675A patent/CH614202A5/en not_active IP Right Cessation
- 1975-04-17 IE IE863/75A patent/IE41112B1/en unknown
- 1975-04-17 LU LU72307A patent/LU72307A1/xx unknown
-
1979
- 1979-02-19 CH CH160679A patent/CH615672A5/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2143234A (en) * | 1983-07-06 | 1985-02-06 | Shinogi Seiyaku Kabushiki Kais | (oxoheterocyclic carbonamido) cephem carboxylic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
DD119784A5 (en) | 1976-05-12 |
SU564811A3 (en) | 1977-07-05 |
CH615672A5 (en) | 1980-02-15 |
NO144070B (en) | 1981-03-09 |
CH614202A5 (en) | 1979-11-15 |
NO144070C (en) | 1981-06-17 |
SE7503524L (en) | 1975-10-20 |
AR206143A1 (en) | 1976-06-30 |
DE2516555A1 (en) | 1975-10-30 |
SE418613B (en) | 1981-06-15 |
NO751352L (en) | 1975-10-20 |
FI751129A (en) | 1975-10-18 |
LU72307A1 (en) | 1976-03-17 |
FR2267771A1 (en) | 1975-11-14 |
JPS50148352A (en) | 1975-11-27 |
IE41112B1 (en) | 1979-10-24 |
DK164075A (en) | 1975-10-18 |
FR2267771B1 (en) | 1978-08-18 |
YU96275A (en) | 1983-04-27 |
IE41112L (en) | 1975-10-17 |
AU8013675A (en) | 1976-10-21 |
ES436649A1 (en) | 1977-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |