IE40905L - Substituted triphenylethylenes - Google Patents
Substituted triphenylethylenesInfo
- Publication number
- IE40905L IE40905L IE750743A IE74375A IE40905L IE 40905 L IE40905 L IE 40905L IE 750743 A IE750743 A IE 750743A IE 74375 A IE74375 A IE 74375A IE 40905 L IE40905 L IE 40905L
- Authority
- IE
- Ireland
- Prior art keywords
- denotes
- lower alkyl
- hydrogen
- formula
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pharmacologically active compounds of the formula Ia <IMAGE> or an acid addition salt thereof, wherein X denotes an R<6>SO2- group, R<1> and R<2> denote lower alkyl or together with the nitrogen atom to which they are bonded form a heterocyclic ring, R<3> and R<4> denote hydrogen, hydroxyl or methoxy, R<5> denotes hydrogen, halogen, nitro or lower alkyl or perfluoroalkyl, R<6> denotes lower alkyl and n denotes 2 or 3, are prepared by dehydration in that a solution of the corresponding triphenylethanols is heated in the presence of an acid. One application of this process is the preparation of compounds of the formula Ia, in which X is hydrogen, by catalytic elimination of the R<6>SO2- group by means of lithium aluminium chloride. The products have various valuable pharmacological properties and are in particular oestrogenically active, possess a post-coital anti-fertile action and furthermore exhibit anti-tumour activity.
[GB1481648A]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45793274A | 1974-04-04 | 1974-04-04 | |
US05/457,931 US4001229A (en) | 1974-04-04 | 1974-04-04 | Alkanesulfonamido triphenylethylenes |
Publications (2)
Publication Number | Publication Date |
---|---|
IE40905L true IE40905L (en) | 1975-10-04 |
IE40905B1 IE40905B1 (en) | 1979-09-12 |
Family
ID=27038784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE743/75A IE40905B1 (en) | 1974-04-04 | 1975-04-03 | Substituted triphenylethylenes |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS50137965A (en) |
CH (1) | CH614192A5 (en) |
DE (1) | DE2514809A1 (en) |
DK (1) | DK135375A (en) |
FR (2) | FR2266494B1 (en) |
GB (1) | GB1481648A (en) |
IE (1) | IE40905B1 (en) |
LU (1) | LU72188A1 (en) |
NL (1) | NL7503855A (en) |
SE (1) | SE418179B (en) |
YU (1) | YU71175A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4572884A (en) * | 1982-11-25 | 1986-02-25 | Ricoh Company, Ltd. | Stilbene derivatives and electrophotographic photoconductor comprising one stilbene derivative |
-
1975
- 1975-03-24 YU YU00711/75A patent/YU71175A/en unknown
- 1975-03-26 DK DK135375A patent/DK135375A/da unknown
- 1975-03-28 FR FR7509807A patent/FR2266494B1/fr not_active Expired
- 1975-04-01 NL NL7503855A patent/NL7503855A/en not_active Application Discontinuation
- 1975-04-01 SE SE7503725A patent/SE418179B/en unknown
- 1975-04-02 LU LU72188A patent/LU72188A1/xx unknown
- 1975-04-03 GB GB13684/75A patent/GB1481648A/en not_active Expired
- 1975-04-03 IE IE743/75A patent/IE40905B1/en unknown
- 1975-04-03 JP JP50039876A patent/JPS50137965A/ja active Pending
- 1975-04-04 CH CH430375A patent/CH614192A5/en not_active IP Right Cessation
- 1975-04-04 DE DE19752514809 patent/DE2514809A1/en active Pending
-
1978
- 1978-08-31 FR FR7825227A patent/FR2391724A1/en active Granted
Also Published As
Publication number | Publication date |
---|---|
DK135375A (en) | 1975-10-05 |
FR2391724A1 (en) | 1978-12-22 |
SE418179B (en) | 1981-05-11 |
DE2514809A1 (en) | 1975-10-16 |
LU72188A1 (en) | 1976-03-02 |
YU71175A (en) | 1982-06-18 |
NL7503855A (en) | 1975-10-07 |
GB1481648A (en) | 1977-08-03 |
FR2266494B1 (en) | 1980-02-08 |
AU7892475A (en) | 1976-09-16 |
SE7503725L (en) | 1975-10-06 |
FR2266494A1 (en) | 1975-10-31 |
JPS50137965A (en) | 1975-11-01 |
CH614192A5 (en) | 1979-11-15 |
FR2391724B1 (en) | 1981-12-04 |
IE40905B1 (en) | 1979-09-12 |
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