IE40644B1 - N-deacylation of 7-acylamido-3-hydroxymethyl cephalosporins - Google Patents
N-deacylation of 7-acylamido-3-hydroxymethyl cephalosporinsInfo
- Publication number
- IE40644B1 IE40644B1 IE1626/74A IE162674A IE40644B1 IE 40644 B1 IE40644 B1 IE 40644B1 IE 1626/74 A IE1626/74 A IE 1626/74A IE 162674 A IE162674 A IE 162674A IE 40644 B1 IE40644 B1 IE 40644B1
- Authority
- IE
- Ireland
- Prior art keywords
- acylamido
- deacylation
- group
- iminoether
- imide
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 238000005947 deacylation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- CZTQZXZIADLWOZ-CRAIPNDOSA-N cefaloridine Chemical compound O=C([C@@H](NC(=O)CC=1SC=CC=1)[C@H]1SC2)N1C(C(=O)[O-])=C2C[N+]1=CC=CC=C1 CZTQZXZIADLWOZ-CRAIPNDOSA-N 0.000 abstract 1
- 229960003866 cefaloridine Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3649773A GB1459212A (en) | 1973-08-01 | 1973-08-01 | N-deacylation of 7-acylamido-3-hydroxy-methyl cephalosporins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40644L IE40644L (en) | 1975-02-01 |
| IE40644B1 true IE40644B1 (en) | 1979-07-18 |
Family
ID=10388710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1626/74A IE40644B1 (en) | 1973-08-01 | 1974-07-31 | N-deacylation of 7-acylamido-3-hydroxymethyl cephalosporins |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS6326112B2 (cs) |
| AT (1) | AT338973B (cs) |
| BE (1) | BE818366A (cs) |
| CH (1) | CH614958A5 (cs) |
| DE (1) | DE2436771C2 (cs) |
| DK (1) | DK146853C (cs) |
| ES (1) | ES428800A1 (cs) |
| FR (1) | FR2254574B1 (cs) |
| GB (1) | GB1459212A (cs) |
| IE (1) | IE40644B1 (cs) |
| NL (1) | NL7410295A (cs) |
| SE (1) | SE431754B (cs) |
| ZA (1) | ZA744904B (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0238060B1 (en) | 1986-03-19 | 1992-01-08 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives, processes for their preparation and antibacterial agents |
| JP4659959B2 (ja) * | 2000-09-29 | 2011-03-30 | 大塚化学株式会社 | 3−セフェム化合物及びその製造法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK118506B (da) * | 1963-02-18 | 1970-08-31 | Ciba Geigy | Fremgangsmåde til fremstilling af 7-aminocephalosporansyre eller estere deraf. |
| GB1241657A (en) * | 1967-08-21 | 1971-08-04 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin compounds |
-
1973
- 1973-08-01 GB GB3649773A patent/GB1459212A/en not_active Expired
-
1974
- 1974-07-31 ES ES428800A patent/ES428800A1/es not_active Expired
- 1974-07-31 DE DE2436771A patent/DE2436771C2/de not_active Expired
- 1974-07-31 ZA ZA00744904A patent/ZA744904B/xx unknown
- 1974-07-31 FR FR7426657A patent/FR2254574B1/fr not_active Expired
- 1974-07-31 DK DK408774A patent/DK146853C/da not_active IP Right Cessation
- 1974-07-31 JP JP49087088A patent/JPS6326112B2/ja not_active Expired
- 1974-07-31 IE IE1626/74A patent/IE40644B1/xx unknown
- 1974-07-31 AT AT628474A patent/AT338973B/de not_active IP Right Cessation
- 1974-07-31 CH CH1051974A patent/CH614958A5/xx not_active IP Right Cessation
- 1974-07-31 NL NL7410295A patent/NL7410295A/xx not_active Application Discontinuation
- 1974-07-31 SE SE7409887A patent/SE431754B/xx unknown
- 1974-08-01 BE BE147179A patent/BE818366A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH614958A5 (en) | 1979-12-28 |
| JPS6326112B2 (cs) | 1988-05-27 |
| AU7188174A (en) | 1976-02-05 |
| AT338973B (de) | 1977-09-26 |
| GB1459212A (en) | 1976-12-22 |
| DE2436771C2 (de) | 1985-10-10 |
| IE40644L (en) | 1975-02-01 |
| SE7409887L (cs) | 1975-02-03 |
| FR2254574B1 (cs) | 1977-10-14 |
| NL7410295A (nl) | 1975-02-04 |
| DE2436771A1 (de) | 1975-02-20 |
| JPS5076089A (cs) | 1975-06-21 |
| ATA628474A (de) | 1977-01-15 |
| ZA744904B (en) | 1975-08-27 |
| FR2254574A1 (cs) | 1975-07-11 |
| ES428800A1 (es) | 1976-12-01 |
| SE431754B (sv) | 1984-02-27 |
| DK146853B (da) | 1984-01-23 |
| BE818366A (fr) | 1975-02-03 |
| DK146853C (da) | 1984-08-06 |
| DK408774A (cs) | 1975-04-01 |
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