IE40157B1 - Prostanoic acid derivatives - Google Patents
Prostanoic acid derivativesInfo
- Publication number
- IE40157B1 IE40157B1 IE1472/74A IE147274A IE40157B1 IE 40157 B1 IE40157 B1 IE 40157B1 IE 1472/74 A IE1472/74 A IE 1472/74A IE 147274 A IE147274 A IE 147274A IE 40157 B1 IE40157 B1 IE 40157B1
- Authority
- IE
- Ireland
- Prior art keywords
- trimethylsilyloxy
- cis
- tetranor
- vinylene
- trans
- Prior art date
Links
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title 1
- -1 3 - chlorophenoxy Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3669173A GB1451798A (en) | 1973-08-02 | 1973-08-02 | Prostanoic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40157L IE40157L (en) | 1975-02-02 |
| IE40157B1 true IE40157B1 (en) | 1979-03-28 |
Family
ID=10390378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1472/74A IE40157B1 (en) | 1973-08-02 | 1974-07-12 | Prostanoic acid derivatives |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US3954881A (enExample) |
| JP (1) | JPS5069045A (enExample) |
| AR (1) | AR204013A1 (enExample) |
| AT (1) | AT341119B (enExample) |
| BE (1) | BE818396A (enExample) |
| CH (1) | CH605511A5 (enExample) |
| CS (1) | CS174785B2 (enExample) |
| DD (1) | DD114401A5 (enExample) |
| DE (1) | DE2437388A1 (enExample) |
| DK (1) | DK410174A (enExample) |
| EG (1) | EG11489A (enExample) |
| ES (1) | ES428889A1 (enExample) |
| FI (1) | FI232274A7 (enExample) |
| FR (1) | FR2239995B1 (enExample) |
| GB (1) | GB1451798A (enExample) |
| IE (1) | IE40157B1 (enExample) |
| IL (1) | IL45299A (enExample) |
| IN (1) | IN138940B (enExample) |
| LU (1) | LU70639A1 (enExample) |
| NL (1) | NL7410343A (enExample) |
| NO (1) | NO742713L (enExample) |
| SE (1) | SE7409930L (enExample) |
| ZA (1) | ZA744509B (enExample) |
| ZM (1) | ZM12074A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1468830A (en) * | 1974-01-26 | 1977-03-30 | May & Baker Ltd | Cyclopentane derivatives |
| US4183870A (en) * | 1974-01-26 | 1980-01-15 | May & Baker Limited | Cyclopentane derivatives |
| GB1506816A (en) * | 1975-03-31 | 1978-04-12 | Upjohn Co | Prostaglandins |
| NL7605381A (nl) * | 1975-05-26 | 1976-11-30 | Schering Ag | Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking. |
| US4388457A (en) * | 1982-02-11 | 1983-06-14 | University Patents, Inc. | Phyllanthostatin compounds |
| IL93936A (en) * | 1989-03-28 | 1994-06-24 | Abbott Lab | History of 9-dioxo-21,9-epoxy - erythromycin, method of preparation History of 11-oxo and 11-hydroxy, and pharmaceutical preparations containing them |
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US6184250B1 (en) | 1993-08-03 | 2001-02-06 | Alcon Laboratories, Inc. | Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension |
| US5510383A (en) * | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| US5721273A (en) | 1993-12-15 | 1998-02-24 | Alcon Laboratories, Inc. | Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension |
| PT1008588E (pt) * | 1997-02-10 | 2003-09-30 | Ono Pharmaceutical Co | Derivados da 11,15-o-diaklquil-prostaglandina e processo de producao dos mesmos e farmaco que os contem como ingrediente activo |
| US7842677B2 (en) * | 2001-08-29 | 2010-11-30 | Seneb Biosciences, Inc. | Synthetic ganglioside derivatives and compositions thereof |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| WO2006010143A2 (en) | 2004-07-13 | 2006-01-26 | Neose Technologies, Inc. | Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1] |
| JP5948627B2 (ja) | 2004-10-29 | 2016-07-20 | レイショファーム ゲーエムベーハー | 線維芽細胞成長因子（ｆｇｆ）のリモデリングと糖質ペグ化 |
| WO2006052841A2 (en) * | 2004-11-09 | 2006-05-18 | Neose Technologies, Inc. | Glycolipids |
| MX2007008229A (es) | 2005-01-10 | 2007-09-11 | Neose Technologies Inc | Factor estimulador de colonias de granulocitos glicopegilado. |
| EP1871795A4 (en) | 2005-04-08 | 2010-03-31 | Biogenerix Ag | COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| US20080248959A1 (en) | 2006-07-21 | 2008-10-09 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
| WO2008057683A2 (en) | 2006-10-03 | 2008-05-15 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
| PL2144923T3 (pl) | 2007-04-03 | 2013-12-31 | Biogenerix Ag | Sposoby leczenia z użyciem glikopegilowanego G-CSF |
| US9493499B2 (en) | 2007-06-12 | 2016-11-15 | Novo Nordisk A/S | Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography |
| CA2715465C (en) | 2008-02-27 | 2017-03-21 | Novo Nordisk A/S | Conjugated factor viii molecules |
| US20120035120A1 (en) | 2009-03-25 | 2012-02-09 | Seneb Biosciences, Inc. | Glycolipids as treatment for disease |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1334952A (en) * | 1971-01-06 | 1973-10-24 | Ici Ltd | Cyclopentane derivat-ves and a process for their manufacture |
-
1973
- 1973-08-02 GB GB3669173A patent/GB1451798A/en not_active Expired
-
1974
- 1974-01-01 AR AR255032A patent/AR204013A1/es active
- 1974-07-12 IE IE1472/74A patent/IE40157B1/xx unknown
- 1974-07-15 US US05/488,759 patent/US3954881A/en not_active Expired - Lifetime
- 1974-07-15 ZA ZA00744509A patent/ZA744509B/xx unknown
- 1974-07-18 IN IN1602/CAL/74A patent/IN138940B/en unknown
- 1974-07-18 IL IL45299A patent/IL45299A/xx unknown
- 1974-07-23 ZM ZM120/74A patent/ZM12074A1/xx unknown
- 1974-07-25 NO NO742713A patent/NO742713L/no unknown
- 1974-07-31 LU LU70639A patent/LU70639A1/xx unknown
- 1974-07-31 CH CH1055174A patent/CH605511A5/xx not_active IP Right Cessation
- 1974-07-31 DD DD180228A patent/DD114401A5/xx unknown
- 1974-07-31 DK DK410174*A patent/DK410174A/da unknown
- 1974-08-01 SE SE7409930A patent/SE7409930L/xx unknown
- 1974-08-01 BE BE147209A patent/BE818396A/xx unknown
- 1974-08-01 NL NL7410343A patent/NL7410343A/xx not_active Application Discontinuation
- 1974-08-01 CS CS5488A patent/CS174785B2/cs unknown
- 1974-08-01 FR FR7426759A patent/FR2239995B1/fr not_active Expired
- 1974-08-02 ES ES428889A patent/ES428889A1/es not_active Expired
- 1974-08-02 FI FI2322/74A patent/FI232274A7/fi unknown
- 1974-08-02 DE DE2437388A patent/DE2437388A1/de not_active Withdrawn
- 1974-08-02 JP JP49088920A patent/JPS5069045A/ja active Pending
- 1974-08-02 AT AT635674A patent/AT341119B/de not_active IP Right Cessation
- 1974-08-03 EG EG316/74A patent/EG11489A/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| DK410174A (enExample) | 1975-04-01 |
| AT341119B (de) | 1978-01-25 |
| ZM12074A1 (en) | 1976-11-22 |
| FR2239995A1 (enExample) | 1975-03-07 |
| NO742713L (enExample) | 1975-03-03 |
| SE7409930L (enExample) | 1975-02-03 |
| ATA635674A (de) | 1977-05-15 |
| FR2239995B1 (enExample) | 1978-07-21 |
| AR204013A1 (es) | 1975-11-12 |
| DD114401A5 (enExample) | 1975-08-05 |
| CH605511A5 (enExample) | 1978-09-29 |
| IE40157L (en) | 1975-02-02 |
| JPS5069045A (enExample) | 1975-06-09 |
| IL45299A0 (en) | 1974-10-22 |
| BE818396A (fr) | 1975-02-03 |
| CS174785B2 (enExample) | 1977-04-29 |
| GB1451798A (en) | 1976-10-06 |
| EG11489A (en) | 1978-06-30 |
| LU70639A1 (enExample) | 1974-12-10 |
| AU7163574A (en) | 1976-01-29 |
| ES428889A1 (es) | 1976-09-01 |
| DE2437388A1 (de) | 1975-02-13 |
| IL45299A (en) | 1978-06-15 |
| FI232274A7 (enExample) | 1975-02-03 |
| US3954881A (en) | 1976-05-04 |
| NL7410343A (nl) | 1975-02-04 |
| ZA744509B (en) | 1975-07-30 |
| IN138940B (enExample) | 1976-04-17 |
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