IE39999B1 - New halogenopyrazole derivatives, a method for producing them and medicaments containing them - Google Patents

New halogenopyrazole derivatives, a method for producing them and medicaments containing them

Info

Publication number
IE39999B1
IE39999B1 IE1705/74A IE170574A IE39999B1 IE 39999 B1 IE39999 B1 IE 39999B1 IE 1705/74 A IE1705/74 A IE 1705/74A IE 170574 A IE170574 A IE 170574A IE 39999 B1 IE39999 B1 IE 39999B1
Authority
IE
Ireland
Prior art keywords
derivatives
aug
pharmaceutical compositions
inflammatory
halogenopyrazole
Prior art date
Application number
IE1705/74A
Other versions
IE39999L (en
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of IE39999L publication Critical patent/IE39999L/en
Publication of IE39999B1 publication Critical patent/IE39999B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1475806 Pharmaceutical compositions of 5- Halo-1, 3-diphenyl pyrazole-4-acetic acids BYK GULDEN LOMBERG CHEMISCHE FABRIK GmbH 14 Aug 1974 [16 Aug 1973] 35740/74 Heading A5B [Also in Division C2] Pharmaceutical compositions comprising a compound of the formula I in which Ph 1 and Ph 2 are the same or different phenyl radicals in which the substituents thereon, where present, are not hydrolysable and halogen is a fluorine chlorine or bromine atom or their salts with organic or inorganic bases and a pharmaceutically acceptable medicament vehicle show anti-inflammatory, antipyretic and analgesic activity when administered orally, parenterally, topically or rectally. The compositions may also contain other inflammatory agents such as a corticosteroid, analgesics, particularly pyrazolone derivatives e.g. prednisolone and dexamethasone, muscle relaxants such as pyridazine derivatives and carbamates, antiulcerogenics, antiacid materials such as magnesium trisilicate and aluminium hydroxide, substances which encourage local blood circulation such as nicotinic acid derivatives and dimethyl sulphoxide, local anesthetics such as lidocain and vitamins. [GB1475806A]
IE1705/74A 1973-08-16 1974-08-15 New halogenopyrazole derivatives, a method for producing them and medicaments containing them IE39999B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU68238A LU68238A1 (en) 1973-08-16 1973-08-16

Publications (2)

Publication Number Publication Date
IE39999L IE39999L (en) 1975-02-16
IE39999B1 true IE39999B1 (en) 1979-02-14

Family

ID=19727442

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1705/74A IE39999B1 (en) 1973-08-16 1974-08-15 New halogenopyrazole derivatives, a method for producing them and medicaments containing them

Country Status (18)

Country Link
JP (1) JPS5230515B2 (en)
AT (1) AT339892B (en)
BE (1) BE818912A (en)
CA (1) CA1048499A (en)
CH (1) CH601250A5 (en)
DE (2) DE2462459C3 (en)
DK (1) DK136953B (en)
ES (1) ES429247A1 (en)
FI (1) FI57584C (en)
FR (1) FR2240732B1 (en)
GB (1) GB1475806A (en)
IE (1) IE39999B1 (en)
LU (1) LU68238A1 (en)
NL (1) NL169070C (en)
NO (1) NO140733C (en)
SE (1) SE409454B (en)
YU (1) YU222474A (en)
ZA (1) ZA745252B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5297383A (en) * 1976-02-13 1977-08-16 Ngk Spark Plug Co Ceramic honeycomb structures for exhaust gas purification
HUP0304101A3 (en) * 2003-12-22 2008-10-28 Sanofi Aventis Pyrazole derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates

Also Published As

Publication number Publication date
FI57584B (en) 1980-05-30
DK136953C (en) 1978-05-29
FI242274A (en) 1975-02-17
AT339892B (en) 1977-11-10
SE7410419L (en) 1975-02-17
DE2462459A1 (en) 1977-04-07
IE39999L (en) 1975-02-16
BE818912A (en) 1975-02-17
LU68238A1 (en) 1975-05-21
NO140733B (en) 1979-07-23
CH601250A5 (en) 1978-06-30
DE2438779C3 (en) 1979-09-20
DE2438779B2 (en) 1979-01-25
ZA745252B (en) 1976-03-31
ES429247A1 (en) 1976-08-16
DE2462459C3 (en) 1979-10-04
SE409454B (en) 1979-08-20
FR2240732A1 (en) 1975-03-14
DK438174A (en) 1975-04-28
JPS5049278A (en) 1975-05-01
NL169070B (en) 1982-01-04
NL7410921A (en) 1975-02-18
FR2240732B1 (en) 1978-07-21
DE2438779A1 (en) 1975-02-27
JPS5230515B2 (en) 1977-08-09
DE2462459B2 (en) 1979-02-08
DK136953B (en) 1977-12-19
ATA671174A (en) 1977-03-15
FI57584C (en) 1980-09-10
CA1048499A (en) 1979-02-13
YU222474A (en) 1983-04-27
NO140733C (en) 1979-10-31
GB1475806A (en) 1977-06-10
NO742941L (en) 1975-03-17
NL169070C (en) 1982-06-01

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