GB1475806A - Halogen-pyrazole derivatives a method for producing them and medicaments containing them - Google Patents

Halogen-pyrazole derivatives a method for producing them and medicaments containing them

Info

Publication number
GB1475806A
GB1475806A GB3574074A GB3574074A GB1475806A GB 1475806 A GB1475806 A GB 1475806A GB 3574074 A GB3574074 A GB 3574074A GB 3574074 A GB3574074 A GB 3574074A GB 1475806 A GB1475806 A GB 1475806A
Authority
GB
United Kingdom
Prior art keywords
halogen
derivatives
aug
pharmaceutical compositions
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3574074A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of GB1475806A publication Critical patent/GB1475806A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1475806 Pharmaceutical compositions of 5- Halo-1, 3-diphenyl pyrazole-4-acetic acids BYK GULDEN LOMBERG CHEMISCHE FABRIK GmbH 14 Aug 1974 [16 Aug 1973] 35740/74 Heading A5B [Also in Division C2] Pharmaceutical compositions comprising a compound of the formula I in which Ph 1 and Ph 2 are the same or different phenyl radicals in which the substituents thereon, where present, are not hydrolysable and halogen is a fluorine chlorine or bromine atom or their salts with organic or inorganic bases and a pharmaceutically acceptable medicament vehicle show anti-inflammatory, antipyretic and analgesic activity when administered orally, parenterally, topically or rectally. The compositions may also contain other inflammatory agents such as a corticosteroid, analgesics, particularly pyrazolone derivatives e.g. prednisolone and dexamethasone, muscle relaxants such as pyridazine derivatives and carbamates, antiulcerogenics, antiacid materials such as magnesium trisilicate and aluminium hydroxide, substances which encourage local blood circulation such as nicotinic acid derivatives and dimethyl sulphoxide, local anesthetics such as lidocain and vitamins.
GB3574074A 1973-08-16 1974-08-14 Halogen-pyrazole derivatives a method for producing them and medicaments containing them Expired GB1475806A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU68238A LU68238A1 (en) 1973-08-16 1973-08-16

Publications (1)

Publication Number Publication Date
GB1475806A true GB1475806A (en) 1977-06-10

Family

ID=19727442

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3574074A Expired GB1475806A (en) 1973-08-16 1974-08-14 Halogen-pyrazole derivatives a method for producing them and medicaments containing them

Country Status (18)

Country Link
JP (1) JPS5230515B2 (en)
AT (1) AT339892B (en)
BE (1) BE818912A (en)
CA (1) CA1048499A (en)
CH (1) CH601250A5 (en)
DE (2) DE2462459C3 (en)
DK (1) DK136953B (en)
ES (1) ES429247A1 (en)
FI (1) FI57584C (en)
FR (1) FR2240732B1 (en)
GB (1) GB1475806A (en)
IE (1) IE39999B1 (en)
LU (1) LU68238A1 (en)
NL (1) NL169070C (en)
NO (1) NO140733C (en)
SE (1) SE409454B (en)
YU (1) YU222474A (en)
ZA (1) ZA745252B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5297383A (en) * 1976-02-13 1977-08-16 Ngk Spark Plug Co Ceramic honeycomb structures for exhaust gas purification
HUP0304101A3 (en) * 2003-12-22 2008-10-28 Sanofi Aventis Pyrazole derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates

Also Published As

Publication number Publication date
FI57584B (en) 1980-05-30
DK136953C (en) 1978-05-29
FI242274A (en) 1975-02-17
AT339892B (en) 1977-11-10
SE7410419L (en) 1975-02-17
DE2462459A1 (en) 1977-04-07
IE39999L (en) 1975-02-16
BE818912A (en) 1975-02-17
LU68238A1 (en) 1975-05-21
NO140733B (en) 1979-07-23
CH601250A5 (en) 1978-06-30
DE2438779C3 (en) 1979-09-20
DE2438779B2 (en) 1979-01-25
ZA745252B (en) 1976-03-31
ES429247A1 (en) 1976-08-16
DE2462459C3 (en) 1979-10-04
SE409454B (en) 1979-08-20
FR2240732A1 (en) 1975-03-14
DK438174A (en) 1975-04-28
JPS5049278A (en) 1975-05-01
NL169070B (en) 1982-01-04
NL7410921A (en) 1975-02-18
FR2240732B1 (en) 1978-07-21
DE2438779A1 (en) 1975-02-27
JPS5230515B2 (en) 1977-08-09
DE2462459B2 (en) 1979-02-08
DK136953B (en) 1977-12-19
ATA671174A (en) 1977-03-15
FI57584C (en) 1980-09-10
CA1048499A (en) 1979-02-13
YU222474A (en) 1983-04-27
NO140733C (en) 1979-10-31
IE39999B1 (en) 1979-02-14
NO742941L (en) 1975-03-17
NL169070C (en) 1982-06-01

Similar Documents

Publication Publication Date Title
US4016268A (en) Method of combatting gastric ulceration
GEP19960467B (en) Method of producing derivatives of quinoline or their pharmaceutically acceptable esters or acid-additive salts
US3564100A (en) Basically substituted cycloalkene compounds as antitussive agents
ES431425A1 (en) M-phenoxyphenyl propionic acid derivatives and preparation thereof
IE40791B1 (en) Vincamine derivatives
GB1475806A (en) Halogen-pyrazole derivatives a method for producing them and medicaments containing them
EP0206076A2 (en) 1,8-Bridged 4-quinolone-3-carboxylic acids, process for their preparation as well as medicaments containing them, and their use for the preparation of medicaments
US3139381A (en) Process of effecting diuresis with nitro disulfamylaniline compounds
US4256747A (en) Antiphlogistic pharmaceutical compositions and method of use
IE40893B1 (en) 1-oxo-1h-6-substituted pyrimido(1,2-a)quinoline-2-carboxylic acids and derivatives thereof as antiallergy agents
US3060090A (en) Pyrazolidine-quinazolone therapeutic composition
GB1322112A (en) 3,4,5-trimethoxybenzoic acid derivatives and their uses
GB1399469A (en) Amino derivatives of pyrazolopyridine ketones
GB1351505A (en) Terpene derivatives method for their preparation and applications thereof
CA1056306A (en) Pharmaceutical compositions containing 2-naphthyl-butyric acid derivatives
GB1181967A (en) Novel Picoline Derivatives and a Method for the Production Thereof
US3269909A (en) Analgesic methods and compositions of benzoic acid derivatives
GB1174880A (en) Derivatives of alpha-Piperazinophenylacetonitrile and process for manufacture of same
US4621085A (en) 2,4,7-triamino-6-phenylpteridine
US3692827A (en) Derivatives of aminoalkanoic acids
GB1382996A (en) Substituted biphenyls
GB1497004A (en) 1-acyl-1,2,3,4-tetrahydro-6-quinolinols and esters thereof and their preparation
US5128330A (en) Oxazinone substituted phosphines
US3726913A (en) Derivatives of aminoalkanoic acids
GB1186061A (en) Benzonaphthyridine Derivatives

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee