IE39146B1 - Process for the production of n-benzoylindoles - Google Patents
Process for the production of n-benzoylindolesInfo
- Publication number
- IE39146B1 IE39146B1 IE2131/73A IE213173A IE39146B1 IE 39146 B1 IE39146 B1 IE 39146B1 IE 2131/73 A IE2131/73 A IE 2131/73A IE 213173 A IE213173 A IE 213173A IE 39146 B1 IE39146 B1 IE 39146B1
- Authority
- IE
- Ireland
- Prior art keywords
- phch
- nov
- benzoylindoles
- production
- indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Abstract
1417080 Process for benzoylating indoles TROPON GmbH [trading as TROPONWERKE DINKLAGE & CO] 23 Nov 1973 [25 Nov 1972] 54400/73 Heading C2C A process for making compounds of formula wherein R is PhCH 2 - or PhCH 2 O 2 CCH 2 - and X is H, or one or more halogen atoms or functional groups, comprises reacting together in an inert solvent at #100‹ C., the corresponding N-unsubstituted indole and benzoyl chloride, with formation of free HCl. The products may be hydrogenolysed to the corresponding acids, i.e. analogues having otherwise the above structure but containing -CH 2 CO 2 H or -CH 2 CO 2 CH 2 CO 2 H in the 3-position of the indole nucleus.
[GB1417080A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2257867A DE2257867C2 (en) | 1972-11-25 | 1972-11-25 | Process for the preparation of 1-benzoylindole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39146L IE39146L (en) | 1974-05-25 |
| IE39146B1 true IE39146B1 (en) | 1978-08-16 |
Family
ID=5862712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2131/73A IE39146B1 (en) | 1972-11-25 | 1973-11-23 | Process for the production of n-benzoylindoles |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS5327274B2 (en) |
| AT (1) | AT329552B (en) |
| BE (1) | BE807766A (en) |
| CA (1) | CA1002040A (en) |
| CH (1) | CH593256A5 (en) |
| CS (1) | CS192507B2 (en) |
| DD (1) | DD108292A5 (en) |
| DE (1) | DE2257867C2 (en) |
| DK (1) | DK135944C (en) |
| ES (1) | ES420811A1 (en) |
| FI (1) | FI56832C (en) |
| FR (1) | FR2207915B1 (en) |
| GB (1) | GB1417080A (en) |
| HU (1) | HU167187B (en) |
| IE (1) | IE39146B1 (en) |
| IL (1) | IL43686A (en) |
| LU (1) | LU68847A1 (en) |
| NL (1) | NL173638C (en) |
| NO (1) | NO140185C (en) |
| PL (1) | PL91250B1 (en) |
| RO (1) | RO63986A (en) |
| SE (1) | SE397828B (en) |
| SU (1) | SU498905A3 (en) |
| YU (1) | YU35352B (en) |
| ZA (1) | ZA738957B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52156862A (en) * | 1976-06-22 | 1977-12-27 | Hisamitsu Pharmaceut Co Inc | Novel indoleacetic acid ester derivatives |
| JPS53163075U (en) * | 1977-05-27 | 1978-12-20 | ||
| DE3206885A1 (en) * | 1982-02-26 | 1983-09-15 | Troponwerke GmbH & Co KG, 5000 Köln | INDOLDER DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS |
| JPS60112760A (en) * | 1983-11-18 | 1985-06-19 | Green Cross Corp:The | Indoleacetic acid derivative and fatty emulsion thereof |
| US7632955B2 (en) | 2001-12-13 | 2009-12-15 | National Health Research Institutes | Indole compounds |
| NO317776B1 (en) | 2003-04-14 | 2004-12-13 | Bodil Korshamn | children Pose |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3483220A (en) * | 1967-05-03 | 1969-12-09 | Merck & Co Inc | Process for preparing 1-aroylindole-3-acetic acid compounds |
-
1972
- 1972-11-25 DE DE2257867A patent/DE2257867C2/en not_active Expired
-
1973
- 1973-11-08 CA CA185,335A patent/CA1002040A/en not_active Expired
- 1973-11-15 YU YU2959/73A patent/YU35352B/en unknown
- 1973-11-20 DK DK625673A patent/DK135944C/en not_active IP Right Cessation
- 1973-11-21 CS CS738010A patent/CS192507B2/en unknown
- 1973-11-22 RO RO7300076742A patent/RO63986A/en unknown
- 1973-11-22 PL PL1973166694A patent/PL91250B1/pl unknown
- 1973-11-23 AT AT983473A patent/AT329552B/en not_active IP Right Cessation
- 1973-11-23 FR FR7341875A patent/FR2207915B1/fr not_active Expired
- 1973-11-23 LU LU68847A patent/LU68847A1/xx unknown
- 1973-11-23 ZA ZA738957A patent/ZA738957B/en unknown
- 1973-11-23 NO NO4489/73A patent/NO140185C/en unknown
- 1973-11-23 IE IE2131/73A patent/IE39146B1/en unknown
- 1973-11-23 DD DD174857A patent/DD108292A5/xx unknown
- 1973-11-23 SE SE7315928A patent/SE397828B/en unknown
- 1973-11-23 IL IL43686A patent/IL43686A/en unknown
- 1973-11-23 FI FI3611/73A patent/FI56832C/en active
- 1973-11-23 BE BE138138A patent/BE807766A/en not_active IP Right Cessation
- 1973-11-23 CH CH1654873A patent/CH593256A5/xx not_active IP Right Cessation
- 1973-11-23 GB GB5440073A patent/GB1417080A/en not_active Expired
- 1973-11-23 HU HUTO942A patent/HU167187B/hu unknown
- 1973-11-23 SU SU1971581A patent/SU498905A3/en active
- 1973-11-24 ES ES420811A patent/ES420811A1/en not_active Expired
- 1973-11-26 JP JP13251673A patent/JPS5327274B2/ja not_active Expired
- 1973-11-26 NL NLAANVRAGE7316146,A patent/NL173638C/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SU498905A3 (en) | 1976-01-05 |
| DK135944C (en) | 1977-12-12 |
| RO63986A (en) | 1978-08-15 |
| BE807766A (en) | 1974-05-24 |
| ZA738957B (en) | 1974-10-30 |
| AT329552B (en) | 1976-05-25 |
| FR2207915A1 (en) | 1974-06-21 |
| JPS4982657A (en) | 1974-08-08 |
| SE397828B (en) | 1977-11-21 |
| CH593256A5 (en) | 1977-11-30 |
| FI56832B (en) | 1979-12-31 |
| YU35352B (en) | 1980-12-31 |
| NL7316146A (en) | 1974-05-28 |
| NL173638C (en) | 1984-02-16 |
| ATA983473A (en) | 1975-08-15 |
| JPS5327274B2 (en) | 1978-08-07 |
| DD108292A5 (en) | 1974-09-12 |
| IE39146L (en) | 1974-05-25 |
| IL43686A (en) | 1976-10-31 |
| DE2257867A1 (en) | 1974-06-06 |
| ES420811A1 (en) | 1976-04-16 |
| GB1417080A (en) | 1975-12-10 |
| IL43686A0 (en) | 1974-03-14 |
| PL91250B1 (en) | 1977-02-28 |
| CA1002040A (en) | 1976-12-21 |
| AU6278173A (en) | 1975-05-22 |
| YU295973A (en) | 1980-06-30 |
| HU167187B (en) | 1975-08-28 |
| NO140185C (en) | 1979-07-18 |
| LU68847A1 (en) | 1974-01-28 |
| DE2257867C2 (en) | 1982-09-23 |
| FI56832C (en) | 1980-04-10 |
| DK135944B (en) | 1977-07-18 |
| FR2207915B1 (en) | 1978-01-06 |
| CS192507B2 (en) | 1979-08-31 |
| NO140185B (en) | 1979-04-09 |
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