IE38872B1 - Propanolamine derivatives - Google Patents
Propanolamine derivativesInfo
- Publication number
- IE38872B1 IE38872B1 IE02159/73A IE215973A IE38872B1 IE 38872 B1 IE38872 B1 IE 38872B1 IE 02159/73 A IE02159/73 A IE 02159/73A IE 215973 A IE215973 A IE 215973A IE 38872 B1 IE38872 B1 IE 38872B1
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- formula
- reacting
- carbamoylphenoxy
- addition salts
- Prior art date
Links
- 150000003152 propanolamines Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 10
- 239000002253 acid Substances 0.000 abstract 4
- -1 and R<SP>2</SP> is H Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 125000002861 (C1-C4) alkanoyl group Chemical group 0.000 abstract 1
- JZEHWMUIAKALDN-UHFFFAOYSA-N 1-amino-3-phenoxypropan-2-ol Chemical compound NCC(O)COC1=CC=CC=C1 JZEHWMUIAKALDN-UHFFFAOYSA-N 0.000 abstract 1
- USMRCRGLLUQDCZ-UHFFFAOYSA-N 2-[(2-methyl-4-phenylmethoxyphenoxy)methyl]oxirane Chemical compound C(C1=CC=CC=C1)OC1=CC(=C(OCC2CO2)C=C1)C USMRCRGLLUQDCZ-UHFFFAOYSA-N 0.000 abstract 1
- DGFFIQHIMIAQFL-UHFFFAOYSA-N 2-methyl-4-phenylmethoxyphenol Chemical compound C1=C(O)C(C)=CC(OCC=2C=CC=CC=2)=C1 DGFFIQHIMIAQFL-UHFFFAOYSA-N 0.000 abstract 1
- MHIAMONBYDFGFO-UHFFFAOYSA-N 4-(2-aminoethoxy)benzamide Chemical compound NCCOC1=CC=C(C(N)=O)C=C1 MHIAMONBYDFGFO-UHFFFAOYSA-N 0.000 abstract 1
- BFVVMQUMXUYSGM-UHFFFAOYSA-N 4-(2-oxoethoxy)benzamide Chemical compound NC(=O)C1=CC=C(OCC=O)C=C1 BFVVMQUMXUYSGM-UHFFFAOYSA-N 0.000 abstract 1
- KPXRAIKWRMIGLM-UHFFFAOYSA-N 4-[2-(benzylamino)ethoxy]benzamide Chemical compound C1=CC(C(=O)N)=CC=C1OCCNCC1=CC=CC=C1 KPXRAIKWRMIGLM-UHFFFAOYSA-N 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5604672A GB1398738A (en) | 1972-12-05 | 1972-12-05 | Propanolamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38872L IE38872L (en) | 1974-06-05 |
| IE38872B1 true IE38872B1 (en) | 1978-06-21 |
Family
ID=10475588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE02159/73A IE38872B1 (en) | 1972-12-05 | 1973-11-29 | Propanolamine derivatives |
Country Status (13)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165384A (en) * | 1974-11-01 | 1979-08-21 | Aktiebolaget Hassle | Amide substituted phenoxy propanol amines |
| DD144050A5 (de) * | 1978-06-05 | 1980-09-24 | Ciba Geigy Ag | Verfahren zur herstellung von n-alkylierten aminoalkoholen |
| DD150456A5 (de) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols |
| JPS5726653A (en) * | 1980-05-09 | 1982-02-12 | Ciba Geigy Ag | Substituted phenyl ether |
| GR74992B (enrdf_load_stackoverflow) * | 1980-08-13 | 1984-07-12 | Ciba Geigy Ag | |
| US5254595A (en) * | 1988-12-23 | 1993-10-19 | Elf Sanofi | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA957364A (en) * | 1968-11-18 | 1974-11-05 | Pfizer Corporation | Preparation of polar-substituted phenyl propanolamines |
| DE2023829C3 (de) * | 1970-05-15 | 1979-06-21 | Pfizer Corp., Colon (Panama) | Kernsubstituierte 3-Phenoxy-lphenoxyalkyl-amino-propan-2-oIe, Verfahren zu ihrer Herstellung sowie Arzneimittel |
-
1972
- 1972-12-05 GB GB5604672A patent/GB1398738A/en not_active Expired
-
1973
- 1973-11-20 DE DE2357849A patent/DE2357849A1/de active Pending
- 1973-11-28 AU AU62989/73A patent/AU473444B2/en not_active Expired
- 1973-11-29 IE IE02159/73A patent/IE38872B1/xx unknown
- 1973-11-30 BE BE138417A patent/BE808094A/xx unknown
- 1973-11-30 IL IL43726A patent/IL43726A/en unknown
- 1973-11-30 FR FR7342749A patent/FR2208668B1/fr not_active Expired
- 1973-12-03 LU LU68914A patent/LU68914A1/xx unknown
- 1973-12-04 CA CA187,302A patent/CA1020946A/en not_active Expired
- 1973-12-04 CH CH1694873A patent/CH591424A5/xx not_active IP Right Cessation
- 1973-12-05 ES ES421182A patent/ES421182A1/es not_active Expired
- 1973-12-05 NL NL7316652A patent/NL7316652A/xx not_active Application Discontinuation
- 1973-12-05 JP JP48135440A patent/JPS49100046A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE808094A (fr) | 1974-05-30 |
| AU473444B2 (en) | 1976-06-24 |
| AU6298973A (en) | 1975-05-29 |
| IL43726A0 (en) | 1974-03-14 |
| ES421182A1 (es) | 1976-04-16 |
| FR2208668A1 (enrdf_load_stackoverflow) | 1974-06-28 |
| GB1398738A (en) | 1975-06-25 |
| IL43726A (en) | 1977-07-31 |
| NL7316652A (enrdf_load_stackoverflow) | 1974-06-07 |
| LU68914A1 (enrdf_load_stackoverflow) | 1975-08-20 |
| CH591424A5 (enrdf_load_stackoverflow) | 1977-09-15 |
| JPS49100046A (enrdf_load_stackoverflow) | 1974-09-20 |
| DE2357849A1 (de) | 1974-06-06 |
| CA1020946A (en) | 1977-11-15 |
| FR2208668B1 (enrdf_load_stackoverflow) | 1977-01-28 |
| IE38872L (en) | 1974-06-05 |
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