IE38778B1 - New 1,2,4-benzotriazine derivatives - Google Patents
New 1,2,4-benzotriazine derivativesInfo
- Publication number
- IE38778B1 IE38778B1 IE127/74A IE12774A IE38778B1 IE 38778 B1 IE38778 B1 IE 38778B1 IE 127/74 A IE127/74 A IE 127/74A IE 12774 A IE12774 A IE 12774A IE 38778 B1 IE38778 B1 IE 38778B1
- Authority
- IE
- Ireland
- Prior art keywords
- carbon atoms
- formula
- image
- group
- alkoxy
- Prior art date
Links
- GDAXJBDYNVDMDF-UHFFFAOYSA-N 1,2,4-benzotriazine Chemical class N1=NC=NC2=CC=CC=C21 GDAXJBDYNVDMDF-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000003674 animal food additive Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000003795 chemical substances by application Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Paints Or Removers (AREA)
- Fodder In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH155573A CH576231A5 (en) | 1973-02-02 | 1973-02-02 | 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth |
| CH1273373A CH576459A5 (en) | 1973-09-05 | 1973-09-05 | 1,2,4,-benztriazine-1,4-di-N-oxide derivs. - used in veterinary medicine against pathogenic micro-organisms or to promote growth |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38778L IE38778L (en) | 1974-08-02 |
| IE38778B1 true IE38778B1 (en) | 1978-05-24 |
Family
ID=25687988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE127/74A IE38778B1 (en) | 1973-02-02 | 1974-01-22 | New 1,2,4-benzotriazine derivatives |
Country Status (12)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2538179C2 (de) * | 1975-08-27 | 1986-05-28 | Bayer Ag, 5090 Leverkusen | 3-Alkoxy-benzo-1,2,4-triazine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide |
| US4247691A (en) * | 1977-02-22 | 1981-01-27 | Ciba-Geigy Corporation | 1,2,4-Benzotriazine-1,4-di-N-oxides |
| DE2802488A1 (de) * | 1978-01-20 | 1979-07-26 | Bayer Ag | 3-azolyl-benzotriazine und -benzotriazin-1-oxide, verfahren zu ihrer herstellung, sowie ihre verwendung zur bekaempfung von pflanzenkrankheiten |
| NZ194612A (en) * | 1979-08-31 | 1982-12-21 | Ici Australia Ltd | Benzotriazine derivatives intermediates and herbicidal compositions |
| US5175287A (en) * | 1986-09-25 | 1992-12-29 | S R I International | Process for preparing 1,2,4-benzotriazine oxides |
| WO1988002366A1 (en) * | 1986-09-25 | 1988-04-07 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| US5624925A (en) | 1986-09-25 | 1997-04-29 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| IE62911B1 (en) * | 1988-03-18 | 1995-03-08 | Stanford Res Inst Int | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| GR1000941B (el) * | 1989-03-17 | 1993-03-16 | Stanford Res Inst Int | Μεθοδος παρασκευης οξειδιων 1,2,4,βενζοτριαζινης. |
| AU646794B2 (en) | 1989-09-18 | 1994-03-10 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| DE19651415A1 (de) * | 1996-12-11 | 1998-06-18 | Henkel Ecolab Gmbh & Co Ohg | Verfahren zur Instrumentendesinfektion |
| WO2003055482A1 (en) * | 2001-12-21 | 2003-07-10 | Novo Nordisk A/S | Amide derivatives as gk activators |
| EP1531815B1 (en) | 2002-06-27 | 2014-09-24 | Novo Nordisk A/S | Glucokinase activators |
| US20050282814A1 (en) * | 2002-10-03 | 2005-12-22 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
| PT1723128E (pt) | 2004-01-06 | 2013-02-27 | Novo Nordisk As | Heteroaril-ureias e o seu uso como activadores da glicoquinase |
| RU2006139258A (ru) * | 2004-04-08 | 2008-05-20 | Таргеджен, Инк. (US) | Бензотриазиновые ингибиторы киназ |
| AU2005276974B2 (en) * | 2004-08-25 | 2012-08-02 | Targegen, Inc. | Heterocyclic compounds and methods of use |
| US20060292203A1 (en) * | 2005-06-08 | 2006-12-28 | Targegen, Inc. | Methods and compositions for the treatment of ocular disorders |
| US7999114B2 (en) | 2005-07-08 | 2011-08-16 | Novo Nordisk A/S | Dicycloalkylcarbamoyl ureas as glucokinase activators |
| US7884210B2 (en) | 2005-07-14 | 2011-02-08 | Novo Nordisk A/S | Ureido-thiazole glucokinase activators |
| US8604042B2 (en) * | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
| US8133900B2 (en) * | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
| NZ592990A (en) * | 2005-11-01 | 2013-01-25 | Targegen Inc | Bi-aryl meta-pyrimidine inhibitors of kinases |
| WO2008084043A1 (en) | 2007-01-09 | 2008-07-17 | Novo Nordisk A/S | Urea glucokinase activators |
| AU2008204530B2 (en) | 2007-01-11 | 2013-08-01 | Vtv Therapeutics Llc | Urea glucokinase activators |
| WO2012060847A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| WO2013086467A1 (en) * | 2011-12-07 | 2013-06-13 | Sri International | Benzotriazine oxides as drugs targeting mycobacterium tuberculosis |
| CA3093025A1 (en) | 2018-06-12 | 2019-12-19 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| CN115894385A (zh) * | 2023-01-09 | 2023-04-04 | 中国科学院长春应用化学研究所 | 替拉扎明衍生物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957779A (en) * | 1972-11-15 | 1976-05-18 | Bayer Aktiengesellschaft | Benzo-1,2,4-triazines |
| US3991189A (en) * | 1972-11-15 | 1976-11-09 | Bayer Aktiengesellschaft | Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives |
| SE7501624L (US08063081-20111122-C00115.png) * | 1974-03-15 | 1975-09-16 | Ciba Geigy Ag |
-
1974
- 1974-01-22 IE IE127/74A patent/IE38778B1/xx unknown
- 1974-01-22 IL IL44058A patent/IL44058A/xx unknown
- 1974-01-23 CA CA74190796A patent/CA1049014A/en not_active Expired
- 1974-01-30 DE DE2404375A patent/DE2404375A1/de not_active Withdrawn
- 1974-01-31 NL NL7401370A patent/NL7401370A/xx not_active Application Discontinuation
- 1974-02-01 GB GB486274A patent/GB1465405A/en not_active Expired
- 1974-02-01 BE BE140468A patent/BE810511A/xx unknown
- 1974-02-01 FR FR7403419A patent/FR2215967B1/fr not_active Expired
- 1974-02-01 JP JP49014043A patent/JPS49124235A/ja active Pending
- 1974-11-28 SU SU742078807A patent/SU589914A3/ru active
-
1975
- 1975-01-01 AR AR258398A patent/AR207145A1/es active
-
1977
- 1977-10-19 US US05/843,473 patent/US4160833A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS49124235A (US08063081-20111122-C00115.png) | 1974-11-28 |
| AU6485674A (en) | 1975-07-24 |
| SU589914A3 (ru) | 1978-01-25 |
| AR207145A1 (es) | 1976-09-15 |
| CA1049014A (en) | 1979-02-20 |
| US4160833A (en) | 1979-07-10 |
| GB1465405A (en) | 1977-02-23 |
| FR2215967B1 (US08063081-20111122-C00115.png) | 1977-01-28 |
| FR2215967A1 (US08063081-20111122-C00115.png) | 1974-08-30 |
| DE2404375A1 (de) | 1974-08-08 |
| NL7401370A (US08063081-20111122-C00115.png) | 1974-08-06 |
| IE38778L (en) | 1974-08-02 |
| IL44058A (en) | 1978-10-31 |
| IL44058A0 (en) | 1974-05-16 |
| BE810511A (fr) | 1974-08-01 |
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