IE37068L - Inspecting medicinal capsules - Google Patents

Inspecting medicinal capsules

Info

Publication number
IE37068L
IE37068L IE721232A IE123272A IE37068L IE 37068 L IE37068 L IE 37068L IE 721232 A IE721232 A IE 721232A IE 123272 A IE123272 A IE 123272A IE 37068 L IE37068 L IE 37068L
Authority
IE
Ireland
Prior art keywords
defect
built
capsules
deviation
capsule
Prior art date
Application number
IE721232A
Other versions
IE37068B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE37068L publication Critical patent/IE37068L/en
Publication of IE37068B1 publication Critical patent/IE37068B1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/95Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
    • G01N21/9508Capsules; Tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/66Trinkets, e.g. shirt buttons or jewellery items
    • HELECTRICITY
    • H03ELECTRONIC CIRCUITRY
    • H03KPULSE TECHNIQUE
    • H03K23/00Pulse counters comprising counting chains; Frequency dividers comprising counting chains
    • H03K23/78Pulse counters comprising counting chains; Frequency dividers comprising counting chains using opto-electronic devices
    • HELECTRICITY
    • H03ELECTRONIC CIRCUITRY
    • H03MCODING; DECODING; CODE CONVERSION IN GENERAL
    • H03M1/00Analogue/digital conversion; Digital/analogue conversion
    • H03M1/12Analogue/digital converters
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S209/00Classifying, separating, and assorting solids
    • Y10S209/912Endless feed conveyor with means for holding each item individually
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S209/00Classifying, separating, and assorting solids
    • Y10S209/919Rotary feed conveyor

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

An electronically controlled system and method for processing the signals obtained from an optical inspection of rapidly presented and rotated medicinal capsules. Built-in deviations in the capsule structure are differentiated from structural defects which may occur and the decision made to accept or reject each capsule. The occurrence of a defect or a built-in deviation causes photo detectors to have a current spike output. Both the defect and the built-in deviation spikes are converted to digital pulses. The defect pulses are counted and the deviation pulses are used to reset a free-running oscillator controlled counter. A defect in the circumferential vicinity of the built-in deviations causes the built-in deviation counter to be prematurely reset. This causes a defect to be recorded. Each capsule is redundantly examined. A sufficient number of reoccurrences of any defect causes a shift register to be activated which initiates and controls the rejection of the capsule. Optical readouts present the number of rejected and accepted capsules, and the percentage of rejected capsules for each lot of 1,000 capsules which are inspected. [US3757943A]
IE1232/72A 1971-09-27 1972-09-11 Electronic system and method for capsule inspection IE37068B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18394871A 1971-09-27 1971-09-27

Publications (2)

Publication Number Publication Date
IE37068L true IE37068L (en) 1973-03-27
IE37068B1 IE37068B1 (en) 1977-04-27

Family

ID=22674970

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1232/72A IE37068B1 (en) 1971-09-27 1972-09-11 Electronic system and method for capsule inspection

Country Status (26)

Country Link
US (1) US3757943A (en)
JP (1) JPS5418955B2 (en)
KR (1) KR780000018B1 (en)
AR (1) AR222769A1 (en)
AT (1) AT349237B (en)
AU (1) AU462822B2 (en)
BE (1) BE789263A (en)
BR (1) BR7206671D0 (en)
CA (1) CA958100A (en)
CH (1) CH573099A5 (en)
CS (1) CS178118B2 (en)
DD (1) DD99434A5 (en)
DE (1) DE2246491C2 (en)
ES (1) ES407076A1 (en)
FR (1) FR2187119A5 (en)
GB (1) GB1391221A (en)
IE (1) IE37068B1 (en)
IL (1) IL40348A (en)
IT (1) IT966076B (en)
NL (1) NL7212910A (en)
PH (1) PH12229A (en)
PL (1) PL78404B1 (en)
SE (1) SE391983B (en)
SU (1) SU549068A3 (en)
YU (1) YU35679B (en)
ZA (1) ZA726096B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3791516A (en) * 1972-01-10 1974-02-12 Pitney Bowes Inc Batch ticket reader
US3942900A (en) * 1973-05-24 1976-03-09 Smithkline Corporation Quality control monitor for medicinal capsule packaging apparatus
US4170306A (en) * 1976-05-19 1979-10-09 Ultra-Sort Corp. Control apparatus for sorting products
US4082188A (en) * 1976-06-23 1978-04-04 Hoffmann-La Roche Inc. Apparatus for color recognition and defect detection of objects such as capsules
US4143770A (en) * 1976-06-23 1979-03-13 Hoffmann-La Roche Inc. Method and apparatus for color recognition and defect detection of objects such as capsules
US4147619A (en) * 1976-12-09 1979-04-03 Ore-Ida Foods, Inc. Electronic sorting apparatus
US4205752A (en) * 1977-07-13 1980-06-03 Tri/Valley Growers Color sorting of produce
CH642174A5 (en) * 1978-03-17 1984-03-30 Fuji Electric Co Ltd DEVICE FOR CONTROLLING THE APPEARANCE OF SOLID MEDICINE.
JPS55131756A (en) * 1979-04-02 1980-10-13 Fuji Electric Co Ltd Defect detector
US4305816A (en) * 1980-02-11 1981-12-15 Borden, Inc. Apparatus and method for inspecting containers
US4413738A (en) * 1981-03-11 1983-11-08 Owens-Illinois, Inc. Apparatus and method for controlling the inspection of finished products
JPS60114708A (en) * 1983-11-26 1985-06-21 Takeda Chem Ind Ltd Conveying apparatus of solid medical tablet
JPS60114748A (en) * 1983-11-26 1985-06-21 Takeda Chem Ind Ltd Camera inspection method and apparatus for foreign matter on surface of solid agent
IT1181265B (en) * 1984-12-06 1987-09-23 Gd Spa DEVICE FOR THE TRANSFER OF BAR-SHAPED ITEMS
US4695164A (en) * 1985-09-24 1987-09-22 Boehringer Mannheim Gmbh Position detector and mount therefor for a centrifugal analyzer
DE3608989A1 (en) * 1986-03-18 1987-09-24 Lorenz Ing Grad Bohle DEVICE FOR CLASSIFYING PIECE PRODUCTS BY LENGTH
US4882493A (en) * 1988-03-09 1989-11-21 Indiana University Foundation Sample holders or reflectors for intact capsules and tablets and for liquid microcells for use in near-infrared reflectance spectrophotometers
EP0371643A3 (en) * 1988-11-23 1991-05-29 W.R. Grace & Co.-Conn. Improved method and apparatus for inspecting workpieces
US4901865A (en) * 1988-12-23 1990-02-20 Eli Lilly And Company Capsule-inspection apparatus
US5085510A (en) * 1990-08-28 1992-02-04 Pfizer Inc. Pharmaceutical tablet vision inspection system
JP3043924B2 (en) * 1993-07-16 2000-05-22 シオノギクオリカプス株式会社 Appearance inspection device for solid preparations
JPH07130814A (en) * 1993-10-29 1995-05-19 Sony Corp Visual inspection device of ic package
US5661249A (en) * 1994-08-11 1997-08-26 Walter Grassle Gmbh Apparatus and method for inspecting small articles
US6739455B2 (en) * 1999-02-03 2004-05-25 Shionogi Qualicaps Co., Ltd Defective capsule removing mechanism
KR100350855B1 (en) * 2000-12-29 2002-09-05 주식회사옌트 Chip solting unit used for apparatus for inspecting surface mounted chip
ITBO20020433A1 (en) * 2002-07-04 2004-01-05 Ima Spa METHOD FOR OPTO-ELECTRONIC CONTROL OF PHARMACEUTICAL ITEMS
US8121392B2 (en) * 2004-10-25 2012-02-21 Parata Systems, Llc Embedded imaging and control system
JP5138773B2 (en) 2007-07-10 2013-02-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Optical filling control of drug capsules in capsule filling machine
IT1392277B1 (en) * 2008-12-18 2012-02-24 Ima Spa MACHINE AND METHOD TO FILL AND CHECK CAPSULES
BR112013027681B1 (en) * 2011-04-28 2022-07-26 Qualysense Ag APPARATUS FOR CLASSIFICATION OF PARTICLES INTO QUALITY CLASSES AND METHOD FOR CLASSIFICATION OF PARTICLES INTO QUALITY CLASSES
JP5715554B2 (en) * 2011-12-21 2015-05-07 株式会社 日立技研 Industrial product visual inspection support system
DE102013109471B8 (en) * 2013-08-30 2015-02-19 Fette Engineering GmbH Device for filling and closing capsules
CN104257500B (en) * 2014-09-25 2017-05-17 安徽华盛科技控股股份有限公司 Automatic fault alarm system of CIT capsule production line
EP3492395B1 (en) * 2017-11-30 2020-08-12 Harro Höfliger Verpackungsmaschinen GmbH Method and device for metered filling of containers with a product
CN111801085A (en) * 2018-03-07 2020-10-20 Ds技术有限公司 Device for the metered filling of containers with a filling material
US10782343B2 (en) * 2018-04-17 2020-09-22 Nxp Usa, Inc. Digital tests with radiation induced upsets
CN109894388B (en) * 2019-04-23 2020-11-17 无锡传奇科技有限公司 Soft capsule automatic detection system
EP4115871A1 (en) * 2021-07-09 2023-01-11 Harro Höfliger Verpackungsmaschinen GmbH Transfer device for a capsule and capsule filling machine with transfer device
CN115523881B (en) * 2022-08-17 2023-07-21 江苏辰星药业股份有限公司 Wall thickness detection device is used in production of plant hollow capsule

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2633772A (en) * 1949-08-20 1953-04-07 Seagram & Sons Inc Method and apparatus for detecting foreign bodies in containers
DE1122753B (en) * 1955-05-25 1962-01-25 Fernseh Gmbh Method and device for the identification of pictures and objects
US2933255A (en) * 1956-09-04 1960-04-19 Gen Mills Inc Digital correlation device
US3217877A (en) * 1958-10-30 1965-11-16 Shionogi & Co Apparatus for automatically inspecting ampoules
US3528544A (en) * 1967-10-02 1970-09-15 Eisai Co Ltd Method for inspecting liquids for detection of foreign solid matters

Also Published As

Publication number Publication date
SE391983B (en) 1977-03-07
IT966076B (en) 1974-02-11
DE2246491C2 (en) 1983-08-18
IE37068B1 (en) 1977-04-27
AT349237B (en) 1979-03-26
US3757943A (en) 1973-09-11
JPS5418955B2 (en) 1979-07-11
AR222769A1 (en) 1981-06-30
KR780000018B1 (en) 1978-03-04
CH573099A5 (en) 1976-02-27
AU4663372A (en) 1974-03-21
SU549068A3 (en) 1977-02-28
NL7212910A (en) 1973-03-29
BR7206671D0 (en) 1973-08-23
ATA826672A (en) 1978-08-15
DE2246491A1 (en) 1973-04-05
ES407076A1 (en) 1975-11-16
YU35679B (en) 1981-04-30
AU462822B2 (en) 1975-07-10
DD99434A5 (en) 1973-08-05
JPS4843359A (en) 1973-06-22
CS178118B2 (en) 1977-08-31
CA958100A (en) 1974-11-19
BE789263A (en) 1973-03-26
PL78404B1 (en) 1975-06-30
ZA726096B (en) 1974-04-24
PH12229A (en) 1978-11-29
FR2187119A5 (en) 1974-01-11
IL40348A0 (en) 1972-11-28
IL40348A (en) 1975-04-25
YU243072A (en) 1980-09-25
GB1391221A (en) 1975-04-16

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