IE37053B1 - Penicillin and cephalosporin derivatives - Google Patents
Penicillin and cephalosporin derivativesInfo
- Publication number
- IE37053B1 IE37053B1 IE2/73A IE273A IE37053B1 IE 37053 B1 IE37053 B1 IE 37053B1 IE 2/73 A IE2/73 A IE 2/73A IE 273 A IE273 A IE 273A IE 37053 B1 IE37053 B1 IE 37053B1
- Authority
- IE
- Ireland
- Prior art keywords
- acid
- formula
- group
- jan
- hydroxy
- Prior art date
Links
- 229930186147 Cephalosporin Chemical class 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 150000001780 cephalosporins Chemical class 0.000 title abstract 2
- 229930182555 Penicillin Natural products 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical class N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title 1
- 229940049954 penicillin Drugs 0.000 title 1
- -1 D-α-hydroxyisocaproic acid succinimide Chemical compound 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NYHNVHGFPZAZGA-RXMQYKEDSA-N (2r)-2-hydroxyhexanoic acid Chemical compound CCCC[C@@H](O)C(O)=O NYHNVHGFPZAZGA-RXMQYKEDSA-N 0.000 abstract 1
- LVRFTAZAXQPQHI-UHFFFAOYSA-N 2-hydroxy-4-methylvaleric acid Chemical compound CC(C)CC(O)C(O)=O LVRFTAZAXQPQHI-UHFFFAOYSA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical compound ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH572A CH565182A5 (enrdf_load_stackoverflow) | 1972-01-03 | 1972-01-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37053L IE37053L (en) | 1973-07-03 |
| IE37053B1 true IE37053B1 (en) | 1977-04-27 |
Family
ID=4177249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2/73A IE37053B1 (en) | 1972-01-03 | 1973-01-02 | Penicillin and cephalosporin derivatives |
Country Status (16)
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB940712A (en) * | 1961-06-23 | 1963-10-30 | Beecham Res Lab | Improvements in or relating to penicillins |
| FR1393245A (fr) * | 1962-05-21 | 1965-03-26 | Beecham Group Ltd | Procédé de préparation de pénicillines |
| FR1393244A (fr) * | 1962-05-21 | 1965-03-26 | Beecham Group Ltd | Procédé pour la préparation de pénicillines |
| SE311519B (enrdf_load_stackoverflow) * | 1962-12-14 | 1969-06-16 | Astra Ab |
-
0
- BE BE793595D patent/BE793595A/xx unknown
-
1972
- 1972-01-03 CH CH572A patent/CH565182A5/xx not_active IP Right Cessation
- 1972-11-27 ZA ZA728418A patent/ZA728418B/xx unknown
- 1972-12-01 DK DK603572AA patent/DK140553B/da unknown
- 1972-12-01 IL IL40978A patent/IL40978A/xx unknown
- 1972-12-20 DE DE2262472A patent/DE2262472A1/de not_active Withdrawn
- 1972-12-22 PH PH14198A patent/PH11075A/en unknown
- 1972-12-22 NL NL7217543A patent/NL7217543A/xx not_active Application Discontinuation
-
1973
- 1973-01-01 AR AR245959A patent/AR205150A1/es active
- 1973-01-02 SE SE7300033A patent/SE412065B/xx unknown
- 1973-01-02 AT AT1373A patent/AT320153B/de not_active IP Right Cessation
- 1973-01-02 CA CA160,421A patent/CA1001155A/en not_active Expired
- 1973-01-02 IE IE2/73A patent/IE37053B1/xx unknown
- 1973-01-02 GB GB20273A patent/GB1355629A/en not_active Expired
- 1973-01-03 FR FR7300110A patent/FR2181649B1/fr not_active Expired
- 1973-01-03 HU HU73HO1538A patent/HU170008B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4949272A (en) | 1974-05-30 |
| IE37053L (en) | 1973-07-03 |
| CH565182A5 (enrdf_load_stackoverflow) | 1975-08-15 |
| DE2262472A1 (de) | 1973-07-19 |
| HU170008B (en) | 1977-03-28 |
| NL7217543A (enrdf_load_stackoverflow) | 1973-07-05 |
| DK140553C (enrdf_load_stackoverflow) | 1980-02-18 |
| FR2181649B1 (enrdf_load_stackoverflow) | 1976-03-05 |
| PH11075A (en) | 1977-10-25 |
| ZA728418B (en) | 1973-08-29 |
| IL40978A (en) | 1975-10-15 |
| FR2181649A1 (enrdf_load_stackoverflow) | 1973-12-07 |
| BE793595A (fr) | 1973-07-02 |
| AR205150A1 (es) | 1976-04-12 |
| CA1001155A (en) | 1976-12-07 |
| SE412065B (sv) | 1980-02-18 |
| DK140553B (da) | 1979-10-01 |
| AT320153B (de) | 1975-01-27 |
| IL40978A0 (en) | 1973-02-28 |
| GB1355629A (en) | 1974-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3485819A (en) | Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins | |
| GB1495676A (en) | Cephalosporins having an alpha-acylamino-acetic acid side chain | |
| GB1440216A (en) | Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture | |
| GB1401059A (en) | Derivatives of cephalosporins and penicillins | |
| GB1505885A (en) | Substituted cephalosporins | |
| GB1460327A (en) | Cephalosporins | |
| IE33535B1 (en) | New penicillins | |
| GB1364453A (en) | Penicillanic and cepholosporanic acid derivatives | |
| GB1289358A (enrdf_load_stackoverflow) | ||
| US3989693A (en) | 7-Methoxy cyclonexadienylureidocephalosporins | |
| GB1425571A (en) | Penicillins and cephaosporins | |
| IE37053B1 (en) | Penicillin and cephalosporin derivatives | |
| GB1460916A (en) | Preparation of 3-thiolated-7-acylamido-cephalosporanic acid derivatives | |
| GB1426869A (en) | Penicillins | |
| GB1382494A (en) | Acylaminocephalosporanic acids and process for their manufacture | |
| GB1363833A (en) | 3-heterocyclic thiomethylcephalosporins | |
| IE35404L (en) | Penicillins | |
| US4046904A (en) | Novel penicillin, and its preparation and use | |
| GB1389540A (en) | Derivatives of alpha-aminocephalosporins | |
| US3622568A (en) | Oxdiazolyl and thiadiazolyl penicillins | |
| GB1440670A (en) | Lactam derivatives | |
| IE36558L (en) | Esterification of penicillins | |
| FI60018B (fi) | Foerfarande foer framstaellning av antimikroba bensylpenicillansyraderivat | |
| DE2408905A1 (de) | Aminoacylthiocephalosporine | |
| GB1481808A (en) | Cepham derivatives and preparation thereof |