GB940712A - Improvements in or relating to penicillins - Google Patents

Improvements in or relating to penicillins

Info

Publication number
GB940712A
GB940712A GB2277561A GB2277561A GB940712A GB 940712 A GB940712 A GB 940712A GB 2277561 A GB2277561 A GB 2277561A GB 2277561 A GB2277561 A GB 2277561A GB 940712 A GB940712 A GB 940712A
Authority
GB
United Kingdom
Prior art keywords
penicillin
penicillins
benzamido
oxymethyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2277561A
Inventor
John Herbert Charles Nayler
Harry Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Research Laboratories Ltd
Original Assignee
Beecham Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Research Laboratories Ltd filed Critical Beecham Research Laboratories Ltd
Priority to GB2277561A priority Critical patent/GB940712A/en
Publication of GB940712A publication Critical patent/GB940712A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

Penicillins of the formula <FORM:0940712/C2/1> and non-toxic salts thereof, wherein R is hydrogen or an alkyl, aryl or aralkyl group are prepared by hydrogenating in the presence of a catalyst a penicillin of the formula or a non-toxic salt thereof, wherein R1 and R2 are the same or different and each is an aryl, alkoxycarbonyl, aryloxycarbonyl or aralkoxycarbonyl group or R1 is hydrogen. The catalyst is preferably palladium supported on an alkaline earth metal carbonate. Examples describe the production of hydroxymethylpenicillin from dibenzyloxycarbonylamino - oxymethyl-penicillin and from benzamido-oxymethyl-penicillin, of a -hydroxypentylpenicillin from a -benzamidooxypentylpenicillin, and of a -hydroxybenzylpenicillin from a -benzamido-oxybenzylpenicillin. Specification 940,711 is referred to.
GB2277561A 1961-06-23 1961-06-23 Improvements in or relating to penicillins Expired GB940712A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2277561A GB940712A (en) 1961-06-23 1961-06-23 Improvements in or relating to penicillins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2277561A GB940712A (en) 1961-06-23 1961-06-23 Improvements in or relating to penicillins

Publications (1)

Publication Number Publication Date
GB940712A true GB940712A (en) 1963-10-30

Family

ID=10184881

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2277561A Expired GB940712A (en) 1961-06-23 1961-06-23 Improvements in or relating to penicillins

Country Status (1)

Country Link
GB (1) GB940712A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2181649A1 (en) * 1972-01-03 1973-12-07 Hoffmann La Roche

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2181649A1 (en) * 1972-01-03 1973-12-07 Hoffmann La Roche

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