IE37051B1 - Histidine derivatives - Google Patents
Histidine derivativesInfo
- Publication number
- IE37051B1 IE37051B1 IE1803/72A IE180372A IE37051B1 IE 37051 B1 IE37051 B1 IE 37051B1 IE 1803/72 A IE1803/72 A IE 1803/72A IE 180372 A IE180372 A IE 180372A IE 37051 B1 IE37051 B1 IE 37051B1
- Authority
- IE
- Ireland
- Prior art keywords
- pyrrolidine
- histidyl
- reacting
- histidine
- cyclopentylcarbonyl
- Prior art date
Links
- 150000002410 histidine derivatives Chemical class 0.000 title abstract 2
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 12
- JBDSSBMEKXHSJF-UHFFFAOYSA-N cyclopentanecarboxylic acid Chemical compound OC(=O)C1CCCC1 JBDSSBMEKXHSJF-UHFFFAOYSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VQJMAIZOEPPELO-KYGIZGOZSA-N (1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-(2-hydroxy-5-methylhexan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol hydrochloride Chemical compound Cl.CO[C@]12CC[C@@]3(C[C@@H]1C(C)(O)CCC(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 VQJMAIZOEPPELO-KYGIZGOZSA-N 0.000 abstract 1
- TVLAAZVYMRMYSE-VIFPVBQESA-N (2s)-2-amino-3-(1h-imidazol-5-yl)-1-pyrrolidin-1-ylpropan-1-one Chemical compound C([C@H](N)C(=O)N1CCCC1)C1=CNC=N1 TVLAAZVYMRMYSE-VIFPVBQESA-N 0.000 abstract 1
- PDWMECLUAQUZCV-UHFFFAOYSA-N (4-nitrophenyl) cyclopentanecarboxylate Chemical compound C1=CC([N+](=O)[O-])=CC=C1OC(=O)C1CCCC1 PDWMECLUAQUZCV-UHFFFAOYSA-N 0.000 abstract 1
- BTJIUGUIPKRLHP-UHFFFAOYSA-N 4-nitrophenol Chemical compound OC1=CC=C([N+]([O-])=O)C=C1 BTJIUGUIPKRLHP-UHFFFAOYSA-N 0.000 abstract 1
- NBHHIEJKRZCMOX-FVGYRXGTSA-N Cl.N[C@@H](CC1=CNC=N1)C(=O)N1CCCC1 Chemical compound Cl.N[C@@H](CC1=CNC=N1)C(=O)N1CCCC1 NBHHIEJKRZCMOX-FVGYRXGTSA-N 0.000 abstract 1
- 125000002066 L-histidyl group Chemical class [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 abstract 1
- XNSAINXGIQZQOO-UHFFFAOYSA-N L-pyroglutamyl-L-histidyl-L-proline amide Natural products NC(=O)C1CCCN1C(=O)C(NC(=O)C1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-UHFFFAOYSA-N 0.000 abstract 1
- 102100032251 Pro-thyrotropin-releasing hormone Human genes 0.000 abstract 1
- 239000000627 Thyrotropin-Releasing Hormone Substances 0.000 abstract 1
- 101800004623 Thyrotropin-releasing hormone Proteins 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229960002885 histidine Drugs 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000002267 hypothalamic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical compound NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 abstract 1
- 229940034199 thyrotropin-releasing hormone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB269572*[A GB1374317A (en) | 1972-01-20 | 1972-01-20 | Histidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37051L IE37051L (en) | 1974-06-29 |
| IE37051B1 true IE37051B1 (en) | 1977-04-27 |
Family
ID=9744172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1803/72A IE37051B1 (en) | 1972-01-20 | 1972-12-29 | Histidine derivatives |
Country Status (10)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608365A (en) * | 1984-03-30 | 1986-08-26 | University Of Southern California | Treatment of neurologic functions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4829225B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-04-25 | 1973-09-08 |
-
0
- BE BE793987D patent/BE793987A/xx unknown
-
1972
- 1972-01-20 GB GB269572*[A patent/GB1374317A/en not_active Expired
- 1972-12-29 IE IE1803/72A patent/IE37051B1/xx unknown
-
1973
- 1973-01-02 ZA ZA730025A patent/ZA7325B/xx unknown
- 1973-01-09 US US00322124A patent/US3833604A/en not_active Expired - Lifetime
- 1973-01-17 NL NL7300690A patent/NL7300690A/xx unknown
- 1973-01-19 AU AU51274/73A patent/AU466782B2/en not_active Expired
- 1973-01-19 FR FR7301939A patent/FR2181677B1/fr not_active Expired
- 1973-01-19 JP JP48008470A patent/JPS4880557A/ja active Pending
- 1973-01-19 DE DE2302624A patent/DE2302624A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2181677B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-12-31 |
| ZA7325B (en) | 1973-09-26 |
| GB1374317A (en) | 1974-11-20 |
| IE37051L (en) | 1974-06-29 |
| DE2302624A1 (de) | 1973-07-26 |
| BE793987A (fr) | 1973-05-02 |
| JPS4880557A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-10-29 |
| US3833604A (en) | 1974-09-03 |
| AU5127473A (en) | 1974-07-25 |
| AU466782B2 (en) | 1975-11-06 |
| NL7300690A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-07-24 |
| FR2181677A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1464326A (en) | Benzimidazole carbamates | |
| IL43632A (en) | Heptapeptides having gastrin activity | |
| GB1380225A (en) | Biphenylyl- alkanoylaminopyridines and acid addition salts thereof | |
| IE36383B1 (en) | Improvements in or relating to ortho-disubstituted arylguanidines process for their preparation and applications thereof | |
| IE37051B1 (en) | Histidine derivatives | |
| GB1247612A (en) | Lincomycin derivatives and the manufacture thereof | |
| IE37717B1 (en) | N-benzhydryl-n'-p-hydroxybenzyl-piperazines and processes for their manufacture | |
| GB1392364A (en) | Antibiotics | |
| IE33371B1 (en) | Protozoacidally-active substituted guanidines | |
| GB1459943A (en) | Heterocyclic esters of alkylphenyl benzopyrans | |
| GB1476698A (en) | Quinazolinone derivatives and therapeutic compositions containing them | |
| GB1351437A (en) | N-substituted amino acids having antiviral anti-inflammatory or anti-tumour activity | |
| GB1421589A (en) | Salicylanilide derivatives | |
| CA2046337A1 (en) | Improved transdermal system for the administration of pharmacological compounds under ph-controlled conditions | |
| GB1418595A (en) | N- 2-alkoxybenzoyl- amino acids and a process for producing the same | |
| IE35821B1 (en) | Preparation of n-((1-ethyl-2-pyrrolidinyl)-methyl)-2-methoxy-5-sulphamoylbenzamide | |
| GB1525664A (en) | Tripeptides derived from phenylalanine and histidine their preparation and use | |
| GB1173562A (en) | Chloramphenicol Ester Salts, the Preparation therof and Compositions Containing them | |
| IE36346L (en) | 3-heterocyclylthiomethyl cephalosporins | |
| IE43582L (en) | Desoxystreptamine derivatives | |
| IL39743A (en) | 1-isopropyl-4-(4'-fluorophenyl)-7-methyl-2(1h)-quinazolinone,processes for the production thereof and pharmaceutical compositions comprising this compound | |
| GB1368251A (en) | Theophylinylmethylethanoic acid ester | |
| IE37288B1 (en) | Pharmaceutical compositions for use in the treatment of certain respiratory diseases or conditions in prematurely born children | |
| GB1380265A (en) | Thiazole derivatives | |
| GB1471371A (en) | Cyclopenteno-b-pyridine derivative |