IE36529B1 - Esters of betamethasone and its 9alpha-chloro analogue - Google Patents

Esters of betamethasone and its 9alpha-chloro analogue

Info

Publication number
IE36529B1
IE36529B1 IE939/72A IE93972A IE36529B1 IE 36529 B1 IE36529 B1 IE 36529B1 IE 939/72 A IE939/72 A IE 939/72A IE 93972 A IE93972 A IE 93972A IE 36529 B1 IE36529 B1 IE 36529B1
Authority
IE
Ireland
Prior art keywords
hydroxyl
comparison
9alpha
betamethasone
esters
Prior art date
Application number
IE939/72A
Other languages
English (en)
Other versions
IE36529L (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IE36529L publication Critical patent/IE36529L/xx
Publication of IE36529B1 publication Critical patent/IE36529B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE939/72A 1971-07-05 1972-07-04 Esters of betamethasone and its 9alpha-chloro analogue IE36529B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3134971A GB1391443A (en) 1971-07-05 1971-07-05 Ester of betamethasone and its 9alpha-chloro analogue

Publications (2)

Publication Number Publication Date
IE36529L IE36529L (en) 1973-01-05
IE36529B1 true IE36529B1 (en) 1976-11-24

Family

ID=10321802

Family Applications (1)

Application Number Title Priority Date Filing Date
IE939/72A IE36529B1 (en) 1971-07-05 1972-07-04 Esters of betamethasone and its 9alpha-chloro analogue

Country Status (17)

Country Link
JP (1) JPS5644079B1 (enrdf_load_stackoverflow)
AR (2) AR194120A1 (enrdf_load_stackoverflow)
AU (1) AU464251B2 (enrdf_load_stackoverflow)
BE (1) BE785812A (enrdf_load_stackoverflow)
CA (1) CA983919A (enrdf_load_stackoverflow)
CH (1) CH609065A5 (enrdf_load_stackoverflow)
DE (1) DE2232827A1 (enrdf_load_stackoverflow)
DK (1) DK131474B (enrdf_load_stackoverflow)
FR (1) FR2144761B1 (enrdf_load_stackoverflow)
GB (1) GB1391443A (enrdf_load_stackoverflow)
IE (1) IE36529B1 (enrdf_load_stackoverflow)
IL (1) IL39821A (enrdf_load_stackoverflow)
NL (1) NL169882C (enrdf_load_stackoverflow)
NO (1) NO137754C (enrdf_load_stackoverflow)
PH (1) PH13195A (enrdf_load_stackoverflow)
SE (1) SE385904B (enrdf_load_stackoverflow)
ZA (1) ZA724598B (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5024427A (enrdf_load_stackoverflow) * 1973-01-03 1975-03-15
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
JPS6163976U (enrdf_load_stackoverflow) * 1984-10-01 1986-05-01
JP5780521B2 (ja) 2008-05-28 2015-09-16 リベラジェン・バイオファーマ・インコーポレイテッドReveraGen BioPharma,Inc. 疾患を治療するための、NF−κBの非ホルモン性ステロイド調節因子
US9198921B2 (en) 2010-04-05 2015-12-01 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-κB for treatment of disease
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
NL169882C (nl) 1982-09-01
GB1391443A (en) 1975-04-23
IL39821A0 (en) 1972-09-28
JPS5644079B1 (enrdf_load_stackoverflow) 1981-10-16
IL39821A (en) 1976-02-29
CH609065A5 (en) 1979-02-15
DE2232827A1 (de) 1973-01-18
AR194553A1 (es) 1973-07-23
AU4420572A (en) 1974-01-10
BE785812A (fr) 1973-01-04
NO137754B (no) 1978-01-09
ZA724598B (en) 1973-03-28
IE36529L (en) 1973-01-05
CA983919A (en) 1976-02-17
FR2144761B1 (enrdf_load_stackoverflow) 1976-03-05
PH13195A (en) 1980-01-18
AR194120A1 (es) 1973-06-22
SE385904B (sv) 1976-07-26
DK131474B (da) 1975-07-21
NO137754C (no) 1978-04-19
DK131474C (enrdf_load_stackoverflow) 1975-12-08
NL169882B (nl) 1982-04-01
NL7209345A (enrdf_load_stackoverflow) 1973-01-09
AU464251B2 (en) 1975-08-21
FR2144761A1 (enrdf_load_stackoverflow) 1973-02-16

Similar Documents

Publication Publication Date Title
IE36529B1 (en) Esters of betamethasone and its 9alpha-chloro analogue
CA1019763A (en) Process for the manufacture of carboxylic acid chlorides
GB1299136A (en) Improvements in or relating to prostaglandins and the preparation thereof
IE38980L (en) Cephalosporins
GB1363472A (en) 17-chlorosteroids
GB1437152A (enrdf_load_stackoverflow)
IE35194L (en) Manufacture of pregnanes and sulphite esters.
IE43708L (en) D-homosteroid carboxylic acids
GB1487545A (en) Dermatological composition
IE37657L (en) Prednisolone derivative.
IE42283L (en) 6-fluoro-16-methyl-pregna-1,4,8-triene-3,20-diones
CA1034521A (en) PROCESS FOR THE PREPARATION OF 17-ACYL ESTERS OF 17.alpha.,21-DIHYDROXYSTEROIDS OF THE PREGNANE SERIES
AU472988B2 (en) Cycloalkylidenol & cycloalkenol analogues of prostaglandins e & f
IE33346B1 (en) Cyclohexa-1,4-diene-1-acetic acids
GB1434378A (en) Cyano-pregnene compounds
AU478775B2 (en) Novel substituted xanthone carboxylic acid compounds
AU494153B2 (en) 21-(4-n-acetyl-aminoethyl cyclohexane carboxylic acid cortisone derivatives
GB1215161A (en) 9-chloro steroids
GB1479712A (en) 7-amino-3-thiomethyl-cephem-4-carboxylic acid derivatives
JPS5278824A (en) Preparation of carbosylic acid esters
AU496561B2 (en) Substituted ethenylphenoxy-2, 2-dimethyl acetic acid derivatives
AU501434B2 (en) Carboxy-alkylthio) acetic acid composition
IE42054L (en) D-homo-steroids
AU489177B2 (en) Benzalicyolic carboxylic acid derivatives
GB1327980A (en) Bicycloalkanecarboxylic acid derivatives and the preparation thereof