IE36260B1 - Steroidal silyl ethers - Google Patents
Steroidal silyl ethersInfo
- Publication number
- IE36260B1 IE36260B1 IE443/72A IE44372A IE36260B1 IE 36260 B1 IE36260 B1 IE 36260B1 IE 443/72 A IE443/72 A IE 443/72A IE 44372 A IE44372 A IE 44372A IE 36260 B1 IE36260 B1 IE 36260B1
- Authority
- IE
- Ireland
- Prior art keywords
- prepared
- trien
- diol
- estra
- give
- Prior art date
Links
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003637 steroidlike Effects 0.000 title 1
- 238000005574 benzylation reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 230000001590 oxidative effect Effects 0.000 abstract 2
- 238000006884 silylation reaction Methods 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- XHPGJZWWMPBOBZ-UINNUFKUSA-N (8S,9S,13S,14S)-11-hydroxy-13-methyl-3-phenylmethoxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one Chemical compound C(C1=CC=CC=C1)OC1=CC=2CC[C@H]3[C@@H]4CCC([C@@]4(C)CC([C@@H]3C2C=C1)O)=O XHPGJZWWMPBOBZ-UINNUFKUSA-N 0.000 abstract 1
- HLCRYAZDZCJZFG-BDXSIMOUSA-N (8s,9s,13s,14s)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene Chemical compound C1CC2=CC=CC=C2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 HLCRYAZDZCJZFG-BDXSIMOUSA-N 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 238000005905 alkynylation reaction Methods 0.000 abstract 1
- 230000003509 anti-fertility effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000003559 chemosterilizing effect Effects 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- DQEUYIQDSMINEY-UHFFFAOYSA-M magnesium;prop-1-ene;bromide Chemical compound [Mg+2].[Br-].[CH2-]C=C DQEUYIQDSMINEY-UHFFFAOYSA-M 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000003206 sterilizing agent Substances 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13215271A | 1971-04-07 | 1971-04-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36260L IE36260L (en) | 1972-10-07 |
| IE36260B1 true IE36260B1 (en) | 1976-09-29 |
Family
ID=22452727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE443/72A IE36260B1 (en) | 1971-04-07 | 1972-04-06 | Steroidal silyl ethers |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3755384A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS5516160B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU463573B2 (cg-RX-API-DMAC10.html) |
| BE (1) | BE781799A (cg-RX-API-DMAC10.html) |
| CA (1) | CA969538A (cg-RX-API-DMAC10.html) |
| CH (1) | CH583250A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2216495A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK129584B (cg-RX-API-DMAC10.html) |
| ES (1) | ES401515A1 (cg-RX-API-DMAC10.html) |
| FI (1) | FI56846C (cg-RX-API-DMAC10.html) |
| FR (1) | FR2132721B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1367735A (cg-RX-API-DMAC10.html) |
| IE (1) | IE36260B1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL39145A (cg-RX-API-DMAC10.html) |
| IT (1) | IT960311B (cg-RX-API-DMAC10.html) |
| NL (1) | NL7204603A (cg-RX-API-DMAC10.html) |
| SE (2) | SE376767B (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA722343B (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9311686D0 (en) * | 1993-06-05 | 1993-07-21 | Monocon Int Ltd | Vessel repair |
| US6958327B1 (en) | 1999-11-02 | 2005-10-25 | Schering, Ag | 18 Norsteroids as selectively active estrogens |
| US20050282791A1 (en) * | 1999-11-02 | 2005-12-22 | Alexander Hillisch | 18-nor steroids as selectively active estrogens |
| JP2003513102A (ja) * | 1999-11-02 | 2003-04-08 | シエーリング アクチエンゲゼルシャフト | 選択的な作用を有するエストロゲンとしての１８−ノル−ステロイド |
-
1971
- 1971-04-07 US US00132152A patent/US3755384A/en not_active Expired - Lifetime
-
1972
- 1972-04-04 IT IT89515/72A patent/IT960311B/it active
- 1972-04-06 GB GB1583872A patent/GB1367735A/en not_active Expired
- 1972-04-06 CA CA139,063A patent/CA969538A/en not_active Expired
- 1972-04-06 FI FI942/72A patent/FI56846C/fi active
- 1972-04-06 JP JP3395772A patent/JPS5516160B2/ja not_active Expired
- 1972-04-06 ES ES401515A patent/ES401515A1/es not_active Expired
- 1972-04-06 CH CH503672A patent/CH583250A5/xx not_active IP Right Cessation
- 1972-04-06 FR FR7212127A patent/FR2132721B1/fr not_active Expired
- 1972-04-06 IL IL39145A patent/IL39145A/xx unknown
- 1972-04-06 DE DE19722216495 patent/DE2216495A1/de active Pending
- 1972-04-06 IE IE443/72A patent/IE36260B1/xx unknown
- 1972-04-06 NL NL7204603A patent/NL7204603A/xx not_active Application Discontinuation
- 1972-04-06 SE SE7204409A patent/SE376767B/xx unknown
- 1972-04-06 DK DK167272AA patent/DK129584B/da unknown
- 1972-04-07 BE BE781799A patent/BE781799A/xx not_active IP Right Cessation
- 1972-04-07 ZA ZA722343A patent/ZA722343B/xx unknown
-
1974
- 1974-04-07 AU AU40888/72A patent/AU463573B2/en not_active Expired
- 1974-08-19 SE SE7410509A patent/SE396271B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4856660A (cg-RX-API-DMAC10.html) | 1973-08-09 |
| FR2132721A1 (cg-RX-API-DMAC10.html) | 1972-11-24 |
| US3755384A (en) | 1973-08-28 |
| JPS5516160B2 (cg-RX-API-DMAC10.html) | 1980-04-30 |
| AU4088872A (en) | 1973-10-11 |
| FI56846C (fi) | 1980-04-10 |
| NL7204603A (cg-RX-API-DMAC10.html) | 1972-10-10 |
| DE2216495A1 (de) | 1972-10-19 |
| FR2132721B1 (cg-RX-API-DMAC10.html) | 1975-10-31 |
| SE376767B (cg-RX-API-DMAC10.html) | 1975-06-09 |
| CH583250A5 (cg-RX-API-DMAC10.html) | 1976-12-31 |
| DK129584B (da) | 1974-10-28 |
| CA969538A (en) | 1975-06-17 |
| AU463573B2 (en) | 1975-07-14 |
| BE781799A (fr) | 1972-10-09 |
| ES401515A1 (es) | 1975-05-01 |
| DK129584C (cg-RX-API-DMAC10.html) | 1975-04-07 |
| IL39145A (en) | 1975-05-22 |
| IL39145A0 (en) | 1972-06-28 |
| IE36260L (en) | 1972-10-07 |
| SE7410509L (cg-RX-API-DMAC10.html) | 1974-08-19 |
| FI56846B (fi) | 1979-12-31 |
| ZA722343B (en) | 1973-06-27 |
| GB1367735A (en) | 1974-09-25 |
| IT960311B (it) | 1973-11-20 |
| SE396271B (sv) | 1977-09-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2664390B2 (ja) | 新規な１１−アリールステロイド誘導体 | |
| US4139617A (en) | 19-Oxygenated-androst-5-enes for the enhancement of libido | |
| US4087524A (en) | Androst-4-en-19-ols for the enhancement of libido | |
| GB1494097A (en) | D-homo-20-keto-pregnanes | |
| JPH01211597A (ja) | 新規の１１−アリールステロイド化合物 | |
| US4022769A (en) | Androst-4-en-19-ones | |
| IE36260B1 (en) | Steroidal silyl ethers | |
| GB1190403A (en) | 4-Hydroxy-2-Butenoic Acid Lactones | |
| Dorfman et al. | Uterotrophic activity of various phenolic steroids | |
| GB1495531A (en) | 11beta-alkyl steroids of the estrane series | |
| GB1502326A (en) | 11-substituted steroids of the estrane series | |
| US3875188A (en) | 17-Beta-alpha-lower alkyl allene-substituted steroids | |
| US3449495A (en) | Progestational active 17alpha-alkoxy-16-methylene progesterones | |
| US3107257A (en) | 17alpha-(2-alkenyl)estra-1, 3, 5(10)-triene-3, 17beta-diols and esters thereof | |
| IE34308B1 (en) | 11beta,13beta dialkylgona-1,3,5(10)-trien-3-ol 3-cycloalkyl ethers | |
| US3732209A (en) | Novel 17beta-oxygenated cyclopropa(16alpha,17alpha)steroids | |
| CA1069117A (en) | PROCESS FOR THE PREPARATION OF 11.beta.-HYDROXY-18-ALKYL-ESTRANE COMPOUNDS | |
| US3798215A (en) | Propadienyl-substituted carbinols | |
| US3649621A (en) | Novel 3-cyclopentyl ethers of 13-alkylgon-poly-enes | |
| GB1504410A (en) | 11beta-fluoroandrostenes | |
| SE324152B (cg-RX-API-DMAC10.html) | ||
| US3365473A (en) | 13beta-lower alkyl gona-4, 8(14)-dien-3-ones 17 beta process for the production thereof | |
| US3634469A (en) | Methylenated steroids and process | |
| US3691212A (en) | 17alpha-(1',3'-alkadiynyl)-17beta-acyloxy(17beta-aroyloxy) steroids | |
| US3366652A (en) | Novel 17-ethers of 19-nortestosterone |