IE36021B1 - 3-nitroimidazo (1,2-b) pyridazines - Google Patents
3-nitroimidazo (1,2-b) pyridazinesInfo
- Publication number
- IE36021B1 IE36021B1 IE91/72A IE9172A IE36021B1 IE 36021 B1 IE36021 B1 IE 36021B1 IE 91/72 A IE91/72 A IE 91/72A IE 9172 A IE9172 A IE 9172A IE 36021 B1 IE36021 B1 IE 36021B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- compound
- hydrogen
- piperazinyl
- iii
- Prior art date
Links
- YWTZZJSJUVSJKG-UHFFFAOYSA-N 3-nitroimidazo[1,2-b]pyridazine Chemical class C1=CC=NN2C([N+](=O)[O-])=CN=C21 YWTZZJSJUVSJKG-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 20
- 150000001875 compounds Chemical class 0.000 abstract 10
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- FCSKOFQQCWLGMV-UHFFFAOYSA-N 5-{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methylisoxazole Chemical compound O1N=C(C)C=C1CCCCCOC1=CC=C(C=2OCCN=2)C=C1Cl FCSKOFQQCWLGMV-UHFFFAOYSA-N 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 morpholino, imidazolyl Chemical group 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- ZODDGFAZWTZOSI-UHFFFAOYSA-N nitric acid;sulfuric acid Chemical compound O[N+]([O-])=O.OS(O)(=O)=O ZODDGFAZWTZOSI-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11851071A | 1971-02-24 | 1971-02-24 | |
| US11850871A | 1971-02-24 | 1971-02-24 | |
| US13256571A | 1971-04-08 | 1971-04-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36021L IE36021L (en) | 1972-08-24 |
| IE36021B1 true IE36021B1 (en) | 1976-07-21 |
Family
ID=27382178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE91/72A IE36021B1 (en) | 1971-02-24 | 1972-01-25 | 3-nitroimidazo (1,2-b) pyridazines |
Country Status (13)
| Country | Link |
|---|---|
| AR (2) | AR192343A1 (OSRAM) |
| BE (1) | BE779701A (OSRAM) |
| CH (2) | CH576473A5 (OSRAM) |
| DD (1) | DD96071A1 (OSRAM) |
| DE (1) | DE2208830A1 (OSRAM) |
| ES (1) | ES400141A1 (OSRAM) |
| FR (1) | FR2126305B1 (OSRAM) |
| GB (1) | GB1388915A (OSRAM) |
| HU (1) | HU167201B (OSRAM) |
| IE (1) | IE36021B1 (OSRAM) |
| IL (1) | IL38658A (OSRAM) |
| NL (1) | NL7202087A (OSRAM) |
| SE (1) | SE393805B (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4464372A (en) * | 1982-08-16 | 1984-08-07 | Schering Corporation | Imidazo[1,2-b]pyridazines |
| JPH0717971A (ja) * | 1993-07-02 | 1995-01-20 | Takeda Chem Ind Ltd | イミダゾール誘導体、その製造法及び用途 |
-
1972
- 1972-01-25 IE IE91/72A patent/IE36021B1/xx unknown
- 1972-01-28 IL IL38658A patent/IL38658A/en unknown
- 1972-02-11 AR AR240493A patent/AR192343A1/es active
- 1972-02-17 NL NL7202087A patent/NL7202087A/xx unknown
- 1972-02-22 FR FR7205968A patent/FR2126305B1/fr not_active Expired
- 1972-02-23 HU HUAE356A patent/HU167201B/hu unknown
- 1972-02-23 SE SE7202239A patent/SE393805B/xx unknown
- 1972-02-23 BE BE779701A patent/BE779701A/xx unknown
- 1972-02-23 GB GB841772A patent/GB1388915A/en not_active Expired
- 1972-02-24 CH CH1640572*A patent/CH576473A5/xx not_active IP Right Cessation
- 1972-02-24 DD DD161109A patent/DD96071A1/xx unknown
- 1972-02-24 CH CH266572A patent/CH566337A5/xx not_active IP Right Cessation
- 1972-02-24 ES ES0400141A patent/ES400141A1/es not_active Expired
- 1972-02-24 DE DE19722208830 patent/DE2208830A1/de active Pending
- 1972-12-18 AR AR245699A patent/AR192845A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CH576473A5 (OSRAM) | 1976-06-15 |
| ES400141A1 (es) | 1975-07-01 |
| HU167201B (OSRAM) | 1975-09-27 |
| BE779701A (fr) | 1972-08-23 |
| AR192343A1 (es) | 1973-02-14 |
| AR192845A1 (es) | 1973-03-14 |
| GB1388915A (en) | 1975-03-26 |
| FR2126305A1 (OSRAM) | 1972-10-06 |
| DD96071A1 (OSRAM) | 1973-03-12 |
| FR2126305B1 (OSRAM) | 1975-10-31 |
| IE36021L (en) | 1972-08-24 |
| IL38658A (en) | 1976-05-31 |
| SE393805B (sv) | 1977-05-23 |
| CH566337A5 (OSRAM) | 1975-09-15 |
| IL38658A0 (en) | 1972-03-28 |
| NL7202087A (OSRAM) | 1972-08-28 |
| DE2208830A1 (de) | 1972-08-31 |
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