IE35284B1 - Process for the manufacture of quinoline derivatives - Google Patents

Process for the manufacture of quinoline derivatives

Info

Publication number
IE35284B1
IE35284B1 IE319/71A IE31971A IE35284B1 IE 35284 B1 IE35284 B1 IE 35284B1 IE 319/71 A IE319/71 A IE 319/71A IE 31971 A IE31971 A IE 31971A IE 35284 B1 IE35284 B1 IE 35284B1
Authority
IE
Ireland
Prior art keywords
carbinols
quinolyl
epimeric
quinuclidine
ketones
Prior art date
Application number
IE319/71A
Other languages
English (en)
Other versions
IE35284L (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE35284L publication Critical patent/IE35284L/xx
Publication of IE35284B1 publication Critical patent/IE35284B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE319/71A 1970-03-16 1971-03-15 Process for the manufacture of quinoline derivatives IE35284B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2003470A 1970-03-16 1970-03-16

Publications (2)

Publication Number Publication Date
IE35284L IE35284L (en) 1971-09-16
IE35284B1 true IE35284B1 (en) 1976-01-07

Family

ID=21796376

Family Applications (1)

Application Number Title Priority Date Filing Date
IE319/71A IE35284B1 (en) 1970-03-16 1971-03-15 Process for the manufacture of quinoline derivatives

Country Status (14)

Country Link
AT (1) AT341116B (da)
BE (1) BE764252A (da)
CA (1) CA940530A (da)
CH (2) CH590274A5 (da)
DE (1) DE2111938A1 (da)
DK (1) DK137189B (da)
FR (1) FR2100618B1 (da)
GB (1) GB1313963A (da)
IE (1) IE35284B1 (da)
IL (1) IL36400A (da)
NL (1) NL7103506A (da)
PH (1) PH9976A (da)
SE (1) SE395699B (da)
ZA (1) ZA711588B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605916A5 (da) * 1973-12-07 1978-10-13 Hoffmann La Roche
FR2381044A1 (fr) * 1977-02-17 1978-09-15 Hoffmann La Roche Procede pour la preparation de mefloquine
DE2860188D1 (en) * 1977-06-15 1981-01-08 Devinter Sa Novel method for the preparation of quinidine.
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
AU6941200A (en) 1999-08-27 2001-03-26 Ligand Pharmaceuticals Incorporated 8-substituted-6-trifluoromethyl-9-pyrido(3,2-g)quinoline compounds as androgen receptor modulators
BR0013597A (pt) 1999-08-27 2002-07-16 Ligand Pharm Inc Compostos e métodos moduladores de receptor de androgênio
PE20010647A1 (es) 1999-09-14 2001-06-23 Lilly Co Eli Moduladores de receptores de retinoide x (rxr) con perfil farmacologico mejorado

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH533123A (de) * 1968-07-02 1973-01-31 Hoffmann La Roche Verfahren zur Herstellung von Chinolinderivaten

Also Published As

Publication number Publication date
SE395699B (sv) 1977-08-22
CA940530A (en) 1974-01-22
IE35284L (en) 1971-09-16
DK137189C (da) 1978-07-03
FR2100618A1 (da) 1972-03-24
FR2100618B1 (da) 1974-08-23
GB1313963A (en) 1973-04-18
PH9976A (en) 1976-06-16
CH590274A5 (da) 1977-07-29
CH590275A5 (da) 1977-07-29
DK137189B (da) 1978-01-30
IL36400A (en) 1973-07-30
IL36400A0 (en) 1971-05-26
ATA220971A (de) 1977-05-15
AT341116B (de) 1978-01-25
ZA711588B (en) 1971-12-29
DE2111938A1 (de) 1971-10-07
BE764252A (fr) 1971-09-15
NL7103506A (da) 1971-09-20

Similar Documents

Publication Publication Date Title
IE35284B1 (en) Process for the manufacture of quinoline derivatives
IE33812L (en) Quinuclidinyl quinoline derivatives.
JPS51118771A (en) Method for preparing carbostyryl derivatives
IE33474B1 (en) A process for the manufacture of quinoline derivatives
GB1312205A (en) Method and composition for lowering blood pressure
JPS55124792A (en) Flame retardant
GB1236798A (en) New diarylacetamides process for their production and composition containing same
JPS51125239A (en) Process for preparing new bytyrophenone derivatives
JPS5247988A (en) Method of producing l-tartaric acid
IE42966L (en) 8-azaprostaglandins and process for the preparation thereof.
GB1504683A (en) Pharmaceutical compositions containing substituted pyrimido-quinoline derivatives
JPS5225734A (en) Process for preparation of 4-(4'-halogenobenzyloxy)-bonzoyl acetate
JPS55149244A (en) Hydroquinone derivative and its prepartion
GB1288828A (da)
SE7609497L (sv) Forfarande for framstellning av 2-hydroximetyl-3-hydroxi-6-(1-hydroxi-2-t-butylaminoetyl)-pyridin och mellanprodukter derav
GB1380825A (en) Thioesters
JPS54125680A (en) 5-alkoxypicolinic acid ester, its preparation, and hypotensive agent containing the same
JPS5661365A (en) Dimethoxyphthalazinone derivative and its preparation
GB1373878A (en) Prostaglandins and the preparation thereof
JPS5764673A (en) Alpha-substituted phenyl-isovaleric acid dervative, its preparation, and insecticidal agent
GB1511920A (en) 6-aminochroman derivatives and process for preparation thereof
JPS52116482A (en) Carbostyril derivatives and its preparation
JPS5430138A (en) Cyclopropane carboxylate and its preparation
JPS5217441A (en) Process for preparation of p-cyanophenylester of 4-substituted- benzoi c acid
ES8306705A1 (es) "un procedimiento para la preparacion de (arimeltil) fenil-aminociclohexanos y -ciclohexenos".