IL36400A - Process for the manufacture of quinoline derivatives and intermediates therefor - Google Patents

Process for the manufacture of quinoline derivatives and intermediates therefor

Info

Publication number
IL36400A
IL36400A IL36400A IL3640071A IL36400A IL 36400 A IL36400 A IL 36400A IL 36400 A IL36400 A IL 36400A IL 3640071 A IL3640071 A IL 3640071A IL 36400 A IL36400 A IL 36400A
Authority
IL
Israel
Prior art keywords
methoxy
racemic
ethyl
methylenedioxy
quinolyllithium
Prior art date
Application number
IL36400A
Other languages
English (en)
Other versions
IL36400A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL36400A0 publication Critical patent/IL36400A0/xx
Publication of IL36400A publication Critical patent/IL36400A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL36400A 1970-03-16 1971-03-11 Process for the manufacture of quinoline derivatives and intermediates therefor IL36400A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2003470A 1970-03-16 1970-03-16

Publications (2)

Publication Number Publication Date
IL36400A0 IL36400A0 (en) 1971-05-26
IL36400A true IL36400A (en) 1973-07-30

Family

ID=21796376

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36400A IL36400A (en) 1970-03-16 1971-03-11 Process for the manufacture of quinoline derivatives and intermediates therefor

Country Status (14)

Country Link
AT (1) AT341116B (da)
BE (1) BE764252A (da)
CA (1) CA940530A (da)
CH (2) CH590274A5 (da)
DE (1) DE2111938A1 (da)
DK (1) DK137189B (da)
FR (1) FR2100618B1 (da)
GB (1) GB1313963A (da)
IE (1) IE35284B1 (da)
IL (1) IL36400A (da)
NL (1) NL7103506A (da)
PH (1) PH9976A (da)
SE (1) SE395699B (da)
ZA (1) ZA711588B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605916A5 (da) * 1973-12-07 1978-10-13 Hoffmann La Roche
FR2381044A1 (fr) * 1977-02-17 1978-09-15 Hoffmann La Roche Procede pour la preparation de mefloquine
DE2860188D1 (en) * 1977-06-15 1981-01-08 Devinter Sa Novel method for the preparation of quinidine.
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
AU6941200A (en) 1999-08-27 2001-03-26 Ligand Pharmaceuticals Incorporated 8-substituted-6-trifluoromethyl-9-pyrido(3,2-g)quinoline compounds as androgen receptor modulators
BR0013597A (pt) 1999-08-27 2002-07-16 Ligand Pharm Inc Compostos e métodos moduladores de receptor de androgênio
PE20010647A1 (es) 1999-09-14 2001-06-23 Lilly Co Eli Moduladores de receptores de retinoide x (rxr) con perfil farmacologico mejorado

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH533123A (de) * 1968-07-02 1973-01-31 Hoffmann La Roche Verfahren zur Herstellung von Chinolinderivaten

Also Published As

Publication number Publication date
SE395699B (sv) 1977-08-22
CA940530A (en) 1974-01-22
IE35284L (en) 1971-09-16
DK137189C (da) 1978-07-03
FR2100618A1 (da) 1972-03-24
FR2100618B1 (da) 1974-08-23
IE35284B1 (en) 1976-01-07
GB1313963A (en) 1973-04-18
PH9976A (en) 1976-06-16
CH590274A5 (da) 1977-07-29
CH590275A5 (da) 1977-07-29
DK137189B (da) 1978-01-30
IL36400A0 (en) 1971-05-26
ATA220971A (de) 1977-05-15
AT341116B (de) 1978-01-25
ZA711588B (en) 1971-12-29
DE2111938A1 (de) 1971-10-07
BE764252A (fr) 1971-09-15
NL7103506A (da) 1971-09-20

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