IE35133B1 - Acid amides - Google Patents
Acid amidesInfo
- Publication number
- IE35133B1 IE35133B1 IE118/71A IE11871A IE35133B1 IE 35133 B1 IE35133 B1 IE 35133B1 IE 118/71 A IE118/71 A IE 118/71A IE 11871 A IE11871 A IE 11871A IE 35133 B1 IE35133 B1 IE 35133B1
- Authority
- IE
- Ireland
- Prior art keywords
- amide
- vitamin
- acid
- acid amides
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1283887 Vitamin A acid amides F HOFFMANN-LA ROCHE & CO AG 19 April 1971 [2 Feb 1970] 20880/71 Heading C2V Vitamin A acid amides of formula where R and R<SP>1</SP> are alkyl, alkyl substituted by alkoxy, alkyl substituted by dialkyl amino, hydroxy alkyl, phenyl or benzyl groups, are obtained by reacting Vitamin A acid or functional derivative thereof (e.g. an acid halide) with an amine of formula In examples there are prepared Vitamin A acid ethyl amide, methyl amide, isopropyl amide, butyl amide, methyl propyl amide, n-decyl amide, ethanol amide, phenyl amide, diphenyl amide, benzyl amide, 2-diethylamino-ethyl amide, 2-methoxy-ethyl amide, diethyl amide, di-(n-butyl) amide and di-(n-decyl) amide. The above-described Vitamin A acid amides may be formed into pharmaceutical preparations with the usual compatible carrier materials.
[GB1283887A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH142870A CH529742A (en) | 1970-02-02 | 1970-02-02 | Process for the production of vitamin A acid amides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35133L IE35133L (en) | 1971-08-02 |
| IE35133B1 true IE35133B1 (en) | 1975-11-26 |
Family
ID=4210229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE118/71A IE35133B1 (en) | 1970-02-02 | 1971-02-02 | Acid amides |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS544948B1 (en) |
| AT (1) | AT303274B (en) |
| BE (1) | BE762345A (en) |
| CA (1) | CA963910A (en) |
| CH (1) | CH529742A (en) |
| DE (1) | DE2102586C2 (en) |
| DK (1) | DK136311B (en) |
| ES (1) | ES387834A1 (en) |
| FI (1) | FI52715C (en) |
| FR (1) | FR2081477B1 (en) |
| GB (1) | GB1283887A (en) |
| IE (1) | IE35133B1 (en) |
| IL (1) | IL35987A (en) |
| NL (1) | NL168415C (en) |
| NO (1) | NO133802C (en) |
| SE (1) | SE373133B (en) |
| YU (1) | YU34355B (en) |
| ZA (1) | ZA71142B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2300107C2 (en) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A acid anilide-4-carboxylic acid ethyl ester, process for its production and preparations containing it |
| US4310546A (en) * | 1978-07-31 | 1982-01-12 | Johnson & Johnson | Novel retinoids and their use in preventing carcinogenesis |
| DE2843915A1 (en) * | 1978-10-07 | 1980-04-24 | Basf Ag | N-BENZOYL RETINYLAMINE |
| DE2843870A1 (en) * | 1978-10-07 | 1980-04-24 | Basf Ag | N-HYDROXYPROPYLAMIDES OF ALL-E AND 13-Z RETINIC ACID |
| DE3002545A1 (en) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 5-AMINO-TETRAZOLE DERIVATIVES OF RETINIC ACIDS, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| CH651007A5 (en) * | 1982-06-24 | 1985-08-30 | Hoffmann La Roche | POLYEN CONNECTIONS. |
| WO1997009307A1 (en) * | 1995-09-01 | 1997-03-13 | Gist-Brocades B.V. | Retinoylamide based derivatives of sphingoid bases |
| US7566808B2 (en) * | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| WO2006005455A2 (en) * | 2004-07-09 | 2006-01-19 | Dsm Ip Assets B.V. | Amino, amino acid or peptide conjugates of retinoic acid |
| KR100837186B1 (en) * | 2006-09-29 | 2008-06-13 | (주)아모레퍼시픽 | Retinoic acid derivative having anti-aging activity and preparation method thereof |
| US11148998B2 (en) | 2017-05-23 | 2021-10-19 | The Regents Of The University Of Michigan | Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH195065A (en) * | 1936-11-23 | 1938-01-15 | Int Suiker En Alcohol Compagni | Installation on vacuum apparatus to facilitate the replacement of individual tubes. |
| NL257621A (en) * | 1959-11-23 | |||
| FR1297730A (en) * | 1960-11-04 | 1962-07-06 | Hoffmann La Roche | Cosmetic preparation |
| FR1320153A (en) * | 1962-01-22 | 1963-03-08 | Sumitomo Chemical Co | Process for the production of compounds derived from vitamin a 2-trans acid |
-
1970
- 1970-02-02 CH CH142870A patent/CH529742A/en not_active IP Right Cessation
- 1970-12-09 FI FI703317A patent/FI52715C/en active
- 1970-12-15 NL NLAANVRAGE7018260,A patent/NL168415C/en not_active IP Right Cessation
- 1970-12-28 YU YU3184/70A patent/YU34355B/en unknown
-
1971
- 1971-01-11 ZA ZA710142A patent/ZA71142B/en unknown
- 1971-01-12 IL IL35987A patent/IL35987A/en unknown
- 1971-01-20 DE DE2102586A patent/DE2102586C2/en not_active Expired
- 1971-01-29 FR FR7103020A patent/FR2081477B1/fr not_active Expired
- 1971-01-29 CA CA103,975A patent/CA963910A/en not_active Expired
- 1971-01-29 DK DK40571AA patent/DK136311B/en not_active Application Discontinuation
- 1971-02-01 ES ES387834A patent/ES387834A1/en not_active Expired
- 1971-02-01 NO NO343/71*[A patent/NO133802C/no unknown
- 1971-02-01 JP JP356271A patent/JPS544948B1/ja active Pending
- 1971-02-01 AT AT79971A patent/AT303274B/en not_active IP Right Cessation
- 1971-02-01 BE BE762345A patent/BE762345A/en not_active IP Right Cessation
- 1971-02-02 SE SE7101274A patent/SE373133B/xx unknown
- 1971-02-02 IE IE118/71A patent/IE35133B1/en unknown
- 1971-04-19 GB GB20880/71A patent/GB1283887A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2081477A1 (en) | 1971-12-03 |
| NO133802B (en) | 1976-03-22 |
| FR2081477B1 (en) | 1974-03-22 |
| FI52715B (en) | 1977-08-01 |
| YU34355B (en) | 1979-07-10 |
| ES387834A1 (en) | 1973-06-01 |
| DK136311B (en) | 1977-09-26 |
| DE2102586C2 (en) | 1985-03-14 |
| NL168415B (en) | 1981-11-16 |
| IL35987A0 (en) | 1971-03-24 |
| IL35987A (en) | 1974-01-14 |
| FI52715C (en) | 1977-11-10 |
| JPS544948B1 (en) | 1979-03-12 |
| IE35133L (en) | 1971-08-02 |
| CH529742A (en) | 1972-10-31 |
| NL7018260A (en) | 1971-08-04 |
| AT303274B (en) | 1972-11-27 |
| DE2102586A1 (en) | 1971-08-12 |
| SE373133B (en) | 1975-01-27 |
| GB1283887A (en) | 1972-08-02 |
| DK136311C (en) | 1978-02-20 |
| BE762345A (en) | 1971-08-02 |
| ZA71142B (en) | 1971-10-27 |
| NL168415C (en) | 1982-04-16 |
| YU318470A (en) | 1978-12-31 |
| NO133802C (en) | 1976-06-30 |
| CA963910A (en) | 1975-03-04 |
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