IE34433L - Modified allergens - Google Patents

Modified allergens

Info

Publication number
IE34433L
IE34433L IE100170A IE100170A IE34433L IE 34433 L IE34433 L IE 34433L IE 100170 A IE100170 A IE 100170A IE 100170 A IE100170 A IE 100170A IE 34433 L IE34433 L IE 34433L
Authority
IE
Ireland
Prior art keywords
pref
carbodiimide
allergy
modified
modified allergens
Prior art date
Application number
IE100170A
Other versions
IE34433B1 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB23853/70A external-priority patent/GB1282163A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IE34433L publication Critical patent/IE34433L/en
Publication of IE34433B1 publication Critical patent/IE34433B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

The allergy producing properties of the material are lowered by inter and/or intra molecular action. Pref. the material is reacted with a polyaldehyde, polyketone, carbodiimide, epihalohydrin, or inorganic cyanate in acid medium, to give a modified material insoluble or barely soluble in water. Cpds. esp. used are glutaraldehyde, phenylglyoxal, 2-nitroindane-1,3-dione at pH 4-8 or, 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide metho-p-toluenesulphonate, or KCN at pH is approx. 5. Pref. the allergy inducing material is pollen(s). [DE2039223A1]
IE100170A 1969-08-06 1970-08-04 Modified allergens and a process for their preparation IE34433B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB23853/70A GB1282163A (en) 1969-08-06 1969-08-06 Modified allergens and a process for their preparation
GB3928969 1969-08-06
GB2362170 1970-05-15

Publications (2)

Publication Number Publication Date
IE34433L true IE34433L (en) 1971-02-06
IE34433B1 IE34433B1 (en) 1975-05-14

Family

ID=27258241

Family Applications (1)

Application Number Title Priority Date Filing Date
IE100170A IE34433B1 (en) 1969-08-06 1970-08-04 Modified allergens and a process for their preparation

Country Status (12)

Country Link
JP (1) JPS4935413B1 (en)
AT (1) AT297930B (en)
BE (1) BE754523A (en)
CA (1) CA950358A (en)
CH (2) CH569743A5 (en)
DE (1) DE2039223C3 (en)
DK (1) DK127954B (en)
ES (1) ES382486A1 (en)
IE (1) IE34433B1 (en)
NL (1) NL168419C (en)
NO (1) NO135015C (en)
SE (1) SE396694B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1492973A (en) * 1974-02-16 1977-11-23 Beecham Group Ltd Process for preparing injectable compositions
US4234569A (en) * 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
DE19543592C1 (en) * 1995-11-23 1997-02-20 Gsf Forschungszentrum Umwelt Pollen test medium contains pollen slurry in soln. of L-sugars contg. boron cpds.
DE59710863D1 (en) * 1996-01-25 2003-11-20 Schering Ag IMPROVED CONTRAST MEDIUM SOLUTIONS FOR INTRAVASAL APPLICATION
IT1391559B1 (en) * 2008-09-01 2012-01-11 Lofarma Spa ALLERGOIDS DERIVED FROM ALLERGENS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098693A (en) * 1960-05-27 1963-07-23 Little Inc A Treatment of protein and peptide materials to form amide linkages

Also Published As

Publication number Publication date
IE34433B1 (en) 1975-05-14
DK127954B (en) 1974-02-11
NL168419B (en) 1981-11-16
NL168419C (en) 1982-04-16
CH569743A5 (en) 1975-11-28
NO135015B (en) 1976-10-18
NO135015C (en) 1977-01-26
JPS4935413B1 (en) 1974-09-21
SE396694B (en) 1977-10-03
ES382486A1 (en) 1974-06-16
BE754523A (en) 1971-02-08
DE2039223C3 (en) 1981-04-30
CH570418A5 (en) 1975-12-15
NL7011548A (en) 1971-02-09
DE2039223A1 (en) 1971-02-18
DE2039223B2 (en) 1980-08-07
AT297930B (en) 1972-04-10
CA950358A (en) 1974-07-02

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