IE34145B1 - A process for the manufacture of amino acids and derivatives thereof - Google Patents
A process for the manufacture of amino acids and derivatives thereofInfo
- Publication number
- IE34145B1 IE34145B1 IE609/70A IE60970A IE34145B1 IE 34145 B1 IE34145 B1 IE 34145B1 IE 609/70 A IE609/70 A IE 609/70A IE 60970 A IE60970 A IE 60970A IE 34145 B1 IE34145 B1 IE 34145B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- represents hydrogen
- lower alkyl
- hydroxy
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
Abstract
1283804 3,4 - Dihydroxyphenylalanine derivatives F HOFFMANN-LA ROCHE & CO AG 12 May 1970 [14 May 1969] 22808/70 Heading C2C Compounds of Formula I in which R 1 represents hydrogen, hydroxy, lower alkyl, lower alkoxy, halogen, nitro or amino, n stands for 1, 2 or 3, R 2 represents hydrogen or lower alkyl, R 3 represents hydroxy or optionally mono- or di-lower alkyl-substituted amino, R 4 represents hydrogen, lower alkyl, lower alkanoyl or aroyl and R 5 represents hydrogen or lower alkyl, "lower" denoting groups containing up to 6 carbon atoms, and salts thereof, which process comprises subjecting a compound of the general Formula II wherein one of the substituents R 6 and R 7 is hydroxy and the other substituent is lower alkanoyl, aroyl or carboxy, or a salt of such a compound to an oxidative rearrangement and saponifying the carboxylic acid ester obtained and, in any desired sequence, hydrolysing the product obtained if desired, resolving a racemate obtained into its optically active forms, if desired, and converting a product obtained into a salt if desired. Pharmaceutical compositions in conventional forms and having hypotensive and anti- Parkison activity comprise a novel compound of Formula I above, i.e. one in which n is 1 and R 1 is halogen or C 1-6 alkyl provided that R 2 is alkyl when R 1 is in the 2-position and R 2 is alkyl when R 1 is alkyl, and a carrier or diluent. Reference has been directed by the Comptroller to Specification 1,023,204.
[GB1283804A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH735269A CH521313A (en) | 1969-05-14 | 1969-05-14 | Process for the preparation of phenylalamine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IE34145L IE34145L (en) | 1970-11-14 |
IE34145B1 true IE34145B1 (en) | 1975-02-19 |
Family
ID=4323785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE609/70A IE34145B1 (en) | 1969-05-14 | 1970-05-11 | A process for the manufacture of amino acids and derivatives thereof |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5220470B1 (en) |
AT (1) | AT300768B (en) |
BE (1) | BE750209A (en) |
CH (1) | CH521313A (en) |
ES (1) | ES379619A1 (en) |
FR (1) | FR2051524B1 (en) |
GB (1) | GB1283804A (en) |
IE (1) | IE34145B1 (en) |
IL (1) | IL34505A (en) |
NL (1) | NL144592B (en) |
NO (1) | NO127534B (en) |
RO (1) | RO58401A (en) |
SU (1) | SU376935A3 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH647676A5 (en) * | 1978-12-22 | 1985-02-15 | Donald E Panoz | ORAL, PROGRAM RELEASED GALENIC FORMS AND METHODS OF PREPARING THE SAME. |
FR2452922A2 (en) * | 1979-04-02 | 1980-10-31 | Panoz Donald | Controlled release oral galenical formulation - contains active components in micro-granules prepd. under high compression |
JPS5596436A (en) * | 1979-01-19 | 1980-07-22 | Nippon Hodo Co Ltd | Method of preserving soil sample |
JPS6033001U (en) * | 1983-08-12 | 1985-03-06 | 株式会社 長崎機器製作所 | Upper residual air removal device for flexible container containers |
JPS618501U (en) * | 1984-06-19 | 1986-01-18 | 雪印乳業株式会社 | Deaeration bag packaging equipment for powder, etc. |
-
1969
- 1969-05-14 CH CH735269A patent/CH521313A/en not_active IP Right Cessation
-
1970
- 1970-05-08 RO RO63301A patent/RO58401A/ro unknown
- 1970-05-10 IL IL34505A patent/IL34505A/en unknown
- 1970-05-11 BE BE750209D patent/BE750209A/en unknown
- 1970-05-11 IE IE609/70A patent/IE34145B1/en unknown
- 1970-05-11 NO NO01786/70A patent/NO127534B/no unknown
- 1970-05-12 SU SU1443804A patent/SU376935A3/ru active
- 1970-05-12 NL NL707006842A patent/NL144592B/en not_active IP Right Cessation
- 1970-05-12 GB GB22808/70A patent/GB1283804A/en not_active Expired
- 1970-05-13 FR FR7017384A patent/FR2051524B1/fr not_active Expired
- 1970-05-13 AT AT430870A patent/AT300768B/en not_active IP Right Cessation
- 1970-05-13 ES ES379619A patent/ES379619A1/en not_active Expired
- 1970-05-14 JP JP45040578A patent/JPS5220470B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB1283804A (en) | 1972-08-02 |
SU376935A3 (en) | 1973-04-05 |
NL7006842A (en) | 1970-11-17 |
JPS5220470B1 (en) | 1977-06-03 |
ES379619A1 (en) | 1973-01-16 |
NL144592B (en) | 1975-01-15 |
RO58401A (en) | 1975-09-15 |
IE34145L (en) | 1970-11-14 |
NO127534B (en) | 1973-07-09 |
CH521313A (en) | 1972-04-15 |
IL34505A0 (en) | 1970-07-19 |
DE2023461B2 (en) | 1977-06-08 |
FR2051524A1 (en) | 1971-04-09 |
FR2051524B1 (en) | 1974-03-22 |
BE750209A (en) | 1970-11-12 |
DE2023461A1 (en) | 1970-11-19 |
IL34505A (en) | 1974-10-22 |
AT300768B (en) | 1972-08-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1351261A (en) | Preparation of vincamine alkaloids | |
GB1476214A (en) | Dibenzoxepin derivatives process for the preparation thereof and pharmaceutical compositions containing them | |
IE34145B1 (en) | A process for the manufacture of amino acids and derivatives thereof | |
GB1212090A (en) | Aliphatic diol-diones | |
GB1285400A (en) | Esters of substituted anthranilic acid | |
GB1359542A (en) | Diglycidyl derivatives of n-heterocyclic compounds processes for their production and the use thereof | |
GB1301817A (en) | ||
IE35186B1 (en) | Amines and a process for the manufacture thereof | |
GB1219387A (en) | Bicyclo[2.2.2]oct-2-ene-amino acid compounds | |
GB1225019A (en) | Sulphonic acid esters | |
GB1277770A (en) | l-EPHEDRINE SALT OF D(-)-alpha-AZIDOPHENYLACETIC ACID | |
GB1366667A (en) | Bicyclic compounds | |
GB1278368A (en) | Hydroxy-2-piperidinyl carbinols | |
GB1442250A (en) | Preparation of 4-hydroxybenzonitrile derivatives | |
ES421284A1 (en) | Procedure for the preparation of derivatives of pirrocolinacetic acids. (Machine-translation by Google Translate, not legally binding) | |
SU463668A1 (en) | The method of obtaining-anisoyl- (indolyl-3) -propionic acid or its derivatives | |
GB1497723A (en) | Octahydrobenzo-(c)(1,6)-naphthyridine derivative | |
GB1282896A (en) | New 4-oxo-1,4-dihydro-3-quinolyl-carboxylic acid derivatives and process for their preparation | |
GB1412663A (en) | 2- 4-biphenylyl- tetrahydrofurans and pharmaceutical compositions containing them | |
IE34268B1 (en) | Hydrazines and hydrazones of pyrazolopyridine carboxylic acids and esters | |
GB1187733A (en) | 0,3,10-Berbine Derivatives, their Acid Addition Salts, and Process for the Preparation Thereof | |
GB1409772A (en) | Process for the manufacture of 5-amino-2- beta-cyanoethyl-5- cyclohexen-1-one | |
GB1489784A (en) | Pharmaceutically active substituted keto-acid derivatives | |
GB1397697A (en) | Phenoxyalicyclic carboxylic acid derivatives methods of making them and compositions containing them | |
IE33852B1 (en) | Antifibrinolytic compounds |