IE32946B1 - Phenethylamine derivatives and process for the manufacture thereof - Google Patents
Phenethylamine derivatives and process for the manufacture thereofInfo
- Publication number
- IE32946B1 IE32946B1 IE143/69A IE14369A IE32946B1 IE 32946 B1 IE32946 B1 IE 32946B1 IE 143/69 A IE143/69 A IE 143/69A IE 14369 A IE14369 A IE 14369A IE 32946 B1 IE32946 B1 IE 32946B1
- Authority
- IE
- Ireland
- Prior art keywords
- dibenzyloxy
- dibenzoyloxy
- methoxy
- alkoxy
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Abstract
1,208,231. Phenethylamine derivatives. F. HOFFMANN - LA ROCHE & CO. A.G. 30 Jan., 1969 [14 Feb., 1968], No. 5181/69. Heading C2C. Compounds of the general Formula (I) (R 1 , R 2 = OH, C 1-6 alkoxy; R 3 = C 1-6 alkyl) and their salts are prepared by either hydro. genolysing or hydrogenolysing and reducing as the case may require a compound of the Formula (II) (R 4 , R 5 = aralkoxy; C 1-6 alkoxy; R 6 = aralkoxy; X = or hydrolysing a compound of the Formula (III) (R 7 , R 8 = acyloxy, C 1-6 alkoxy; R 9 = acyloxy), optionally followed by salt formation and/or resolution. The preparation of starting materials of Formulµ (II) and (III) by standard methods and of 3,5 - dibenzyloxy - 4 - methoxyphenylacetone, 1 - (3<SP>1</SP>,5<SP>1</SP> - dibenzyloxy - 4 - methoxyphenyl) - 2 - nitropropene, 3<SP>1</SP>,5<SP>1</SP> - dibenzyloxy - 41 - methoxy - (2 - nitro - 1 - butenyl)benzene, 3,5 - dibenzoyloxy - p - anisaldehyde, 3<SP>1</SP>,5<SP>1</SP> - dibenzoyloxy - 4<SP>1</SP> - methoxy - 2 - nitropropenylbenzene, 3,5 - dibenzoyloxy - 4 - methoxyphenylacetone and 3<SP>1</SP>,4<SP>1</SP> - dibenzyloxy - 5<SP>1</SP>- methoxy - 2 - nitropropenylbenzene is described. The compounds of the invention are hypotensive agents and may be administered in the form of pharmaceutical preparations containing them, with or without other (unspecified) active ingredients, in association with a carrier.
[GB1208231A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH219668A CH500163A (en) | 1968-02-14 | 1968-02-14 | Process for the preparation of phenethylamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32946L IE32946L (en) | 1969-08-14 |
| IE32946B1 true IE32946B1 (en) | 1974-01-23 |
Family
ID=4228127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE143/69A IE32946B1 (en) | 1968-02-14 | 1969-02-04 | Phenethylamine derivatives and process for the manufacture thereof |
Country Status (13)
| Country | Link |
|---|---|
| AT (2) | AT289061B (en) |
| BE (1) | BE728327A (en) |
| BR (1) | BR6906186D0 (en) |
| CH (2) | CH500163A (en) |
| DE (1) | DE1907247A1 (en) |
| ES (1) | ES363591A1 (en) |
| FR (1) | FR2011805A1 (en) |
| GB (1) | GB1208231A (en) |
| IE (1) | IE32946B1 (en) |
| IL (1) | IL31513A (en) |
| NL (1) | NL6901894A (en) |
| NO (1) | NO122840B (en) |
| SE (1) | SE367395B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3120419A1 (en) | 2021-03-07 | 2022-09-09 | Jean-Michel SCHULZ | Device with full control, management and steering authority for an on-board fuel or cryogenic fluid storage facility. |
| FR3131359A1 (en) | 2021-12-28 | 2023-06-30 | Jean Michel SCHULZ | STRUCTURALLY OPTIMIZED LIGHTWEIGHT ONBOARD CRYOGENIC TANK |
| FR3135253A1 (en) | 2022-05-09 | 2023-11-10 | Jean-Michel SCHULZ | Hydrogen storage and distribution device for aircraft. |
| FR3136260A1 (en) | 2022-06-01 | 2023-12-08 | Jean Michel SCHULZ | Cryogenic pressurized hydrogen gas generator - cryogenic booster |
-
1968
- 1968-02-14 CH CH219668A patent/CH500163A/en not_active IP Right Cessation
- 1968-02-14 CH CH1734770A patent/CH500941A/en not_active IP Right Cessation
-
1969
- 1969-01-29 IL IL31513A patent/IL31513A/en unknown
- 1969-01-30 GB GB5181/69A patent/GB1208231A/en not_active Expired
- 1969-02-04 IE IE143/69A patent/IE32946B1/en unknown
- 1969-02-06 NL NL6901894A patent/NL6901894A/xx unknown
- 1969-02-07 BR BR206186/69A patent/BR6906186D0/en unknown
- 1969-02-13 NO NO0591/69A patent/NO122840B/no unknown
- 1969-02-13 ES ES363591A patent/ES363591A1/en not_active Expired
- 1969-02-13 DE DE19691907247 patent/DE1907247A1/en active Pending
- 1969-02-13 BE BE728327D patent/BE728327A/xx unknown
- 1969-02-13 AT AT147469A patent/AT289061B/en not_active IP Right Cessation
- 1969-02-13 FR FR6903428A patent/FR2011805A1/fr not_active Withdrawn
- 1969-02-13 AT AT448170A patent/AT289757B/en not_active IP Right Cessation
- 1969-02-14 SE SE02101/69A patent/SE367395B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE367395B (en) | 1974-05-27 |
| IL31513A0 (en) | 1969-03-27 |
| DE1907247A1 (en) | 1969-09-18 |
| IL31513A (en) | 1972-09-28 |
| AT289061B (en) | 1971-04-13 |
| CH500941A (en) | 1970-12-31 |
| BR6906186D0 (en) | 1973-01-16 |
| AT289757B (en) | 1971-05-10 |
| BE728327A (en) | 1969-08-13 |
| FR2011805A1 (en) | 1970-03-13 |
| NL6901894A (en) | 1969-08-18 |
| GB1208231A (en) | 1970-10-07 |
| CH500163A (en) | 1970-12-15 |
| NO122840B (en) | 1971-08-23 |
| ES363591A1 (en) | 1971-01-01 |
| IE32946L (en) | 1969-08-14 |
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