IE32064B1 - Benzene-sulphonamides and process of preparing them - Google Patents
Benzene-sulphonamides and process of preparing themInfo
- Publication number
- IE32064B1 IE32064B1 IE578/68A IE57868A IE32064B1 IE 32064 B1 IE32064 B1 IE 32064B1 IE 578/68 A IE578/68 A IE 578/68A IE 57868 A IE57868 A IE 57868A IE 32064 B1 IE32064 B1 IE 32064B1
- Authority
- IE
- Ireland
- Prior art keywords
- sulphamoyl
- group
- amino
- compound
- chloro
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical class NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- KDNIOKSLVIGAAN-UHFFFAOYSA-N 2-sulfamoylbenzoic acid Chemical class NS(=O)(=O)C1=CC=CC=C1C(O)=O KDNIOKSLVIGAAN-UHFFFAOYSA-N 0.000 abstract 1
- XPWNKJUPBKTKSI-UHFFFAOYSA-N 3-amino-4-chloro-5-sulfamoylbenzoic acid Chemical compound NC1=CC(C(O)=O)=CC(S(N)(=O)=O)=C1Cl XPWNKJUPBKTKSI-UHFFFAOYSA-N 0.000 abstract 1
- AFRAGFLBINOHDV-UHFFFAOYSA-N 4-chloro-3-chlorosulfonyl-5-nitrobenzoic acid Chemical compound OC(=O)C1=CC([N+]([O-])=O)=C(Cl)C(S(Cl)(=O)=O)=C1 AFRAGFLBINOHDV-UHFFFAOYSA-N 0.000 abstract 1
- LYBQQYNSZYSUMT-UHFFFAOYSA-N 4-chloro-3-chlorosulfonylbenzoic acid Chemical compound OC(=O)C1=CC=C(Cl)C(S(Cl)(=O)=O)=C1 LYBQQYNSZYSUMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical class 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000005647 hydrohalogenation reaction Methods 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000005932 reductive alkylation reaction Methods 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- -1 trifluoromethyl- Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB25937/67A GB1217172A (en) | 1967-06-05 | 1967-06-05 | Sulphonamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32064L IE32064L (en) | 1968-12-05 |
| IE32064B1 true IE32064B1 (en) | 1973-04-04 |
Family
ID=10235740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE578/68A IE32064B1 (en) | 1967-06-05 | 1968-05-14 | Benzene-sulphonamides and process of preparing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3560617A (en:Method) |
| AT (2) | AT289762B (en:Method) |
| BE (2) | BE716122A (en:Method) |
| CH (1) | CH509987A (en:Method) |
| DE (1) | DE1768607A1 (en:Method) |
| DK (1) | DK129926B (en:Method) |
| ES (1) | ES354609A1 (en:Method) |
| FR (1) | FR1585914A (en:Method) |
| GB (1) | GB1217172A (en:Method) |
| IE (1) | IE32064B1 (en:Method) |
| IL (1) | IL29985A (en:Method) |
| NL (1) | NL6807809A (en:Method) |
| NO (1) | NO122655B (en:Method) |
| SE (1) | SE355016B (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3953476A (en) * | 1971-12-27 | 1976-04-27 | Merck & Co., Inc. | 3-Amino-5-sulfonylbenzoic acids |
-
1967
- 1967-06-05 GB GB25937/67A patent/GB1217172A/en not_active Expired
-
1968
- 1968-05-14 IL IL29985A patent/IL29985A/en unknown
- 1968-05-14 IE IE578/68A patent/IE32064B1/xx unknown
- 1968-05-31 AT AT1012969A patent/AT289762B/de not_active IP Right Cessation
- 1968-05-31 DK DK256668AA patent/DK129926B/da unknown
- 1968-05-31 AT AT522868A patent/AT284813B/de not_active IP Right Cessation
- 1968-06-01 ES ES354609A patent/ES354609A1/es not_active Expired
- 1968-06-04 CH CH829268A patent/CH509987A/de not_active IP Right Cessation
- 1968-06-04 NO NO2172/68A patent/NO122655B/no unknown
- 1968-06-04 NL NL6807809A patent/NL6807809A/xx unknown
- 1968-06-04 SE SE07475/68A patent/SE355016B/xx unknown
- 1968-06-04 US US734213A patent/US3560617A/en not_active Expired - Lifetime
- 1968-06-05 BE BE716122D patent/BE716122A/xx unknown
- 1968-06-05 FR FR1585914D patent/FR1585914A/fr not_active Expired
- 1968-06-05 BE BE716125D patent/BE716125A/xx unknown
- 1968-06-05 DE DE19681768607 patent/DE1768607A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE355016B (en:Method) | 1973-04-02 |
| BE716125A (en:Method) | 1968-12-05 |
| FR1585914A (en:Method) | 1970-02-06 |
| US3560617A (en) | 1971-02-02 |
| BE716122A (en:Method) | 1968-12-05 |
| ES354609A1 (es) | 1969-11-01 |
| DK129926C (en:Method) | 1975-06-02 |
| GB1217172A (en) | 1970-12-31 |
| IE32064L (en) | 1968-12-05 |
| AT289762B (de) | 1971-05-10 |
| NO122655B (en:Method) | 1971-07-26 |
| NL6807809A (en:Method) | 1968-12-06 |
| CH509987A (de) | 1971-07-15 |
| AT284813B (de) | 1970-09-25 |
| IL29985A (en) | 1971-11-29 |
| DE1768607A1 (de) | 1971-12-30 |
| DK129926B (da) | 1974-12-02 |
| IL29985A0 (en) | 1968-07-25 |
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