HUT75869A - Benzoylecgonine, ecgonine and ecgonidine derivatives - Google Patents
Benzoylecgonine, ecgonine and ecgonidine derivativesInfo
- Publication number
- HUT75869A HUT75869A HU9603443A HU9603443A HUT75869A HU T75869 A HUT75869 A HU T75869A HU 9603443 A HU9603443 A HU 9603443A HU 9603443 A HU9603443 A HU 9603443A HU T75869 A HUT75869 A HU T75869A
- Authority
- HU
- Hungary
- Prior art keywords
- disorders
- ecgonine
- benzoylecgonine
- ecgonidine derivatives
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Non-Portable Lighting Devices Or Systems Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/260,054 US5525613A (en) | 1994-06-16 | 1994-06-16 | Covalently coupled benzoylecgonine ecgonine and ecgonidine |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9603443D0 HU9603443D0 (en) | 1997-02-28 |
HUT75869A true HUT75869A (en) | 1997-05-28 |
HU224634B1 HU224634B1 (hu) | 2005-12-28 |
Family
ID=22987610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9603443A HU224634B1 (hu) | 1994-06-16 | 1995-06-07 | Benzoil-ekgonin-származékok és ezeket tartalmazó gyógyszerkészítmények |
Country Status (21)
Country | Link |
---|---|
US (1) | US5525613A (hu) |
EP (2) | EP0765326B1 (hu) |
JP (1) | JP2951409B2 (hu) |
KR (1) | KR100407458B1 (hu) |
CN (1) | CN1046511C (hu) |
AT (1) | ATE255108T1 (hu) |
AU (1) | AU693571B2 (hu) |
CA (1) | CA2190611A1 (hu) |
DE (1) | DE69532203T2 (hu) |
DK (1) | DK0765326T3 (hu) |
ES (1) | ES2210296T3 (hu) |
HK (1) | HK1012626A1 (hu) |
HU (1) | HU224634B1 (hu) |
IL (1) | IL114177A (hu) |
MX (1) | MX9606374A (hu) |
NO (1) | NO965276D0 (hu) |
NZ (1) | NZ288844A (hu) |
PL (1) | PL186000B1 (hu) |
PT (1) | PT765326E (hu) |
WO (1) | WO1995034561A1 (hu) |
ZA (1) | ZA955002B (hu) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6270766B1 (en) * | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
US5763456A (en) * | 1995-06-07 | 1998-06-09 | Entropin, Inc. | Benzoylecgonine, ecgonine and ecgonidine derivatives |
US6482831B1 (en) | 1994-06-16 | 2002-11-19 | Entropin, Inc. | Covalently coupled benzoylecgonine, egconine and ecgonidine derivatives |
US6103698A (en) | 1997-03-13 | 2000-08-15 | Basf Aktiengesellschaft | Dolastatin-15 derivatives in combination with taxanes |
CA2466062A1 (en) | 2001-11-13 | 2003-05-22 | Entropin, Inc. | Novel benzoylecgonine compositions and methods for producing them |
TW200418856A (en) * | 2002-12-05 | 2004-10-01 | Entropin Inc | Novel tropane esters and methods for producing and using them |
TW200808739A (en) * | 2006-04-06 | 2008-02-16 | Novartis Vaccines & Diagnostic | Quinazolines for PDK1 inhibition |
WO2007137030A2 (en) | 2006-05-19 | 2007-11-29 | Abbott Laboratories | Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2893996A (en) * | 1957-10-14 | 1959-07-07 | Grace W R & Co | N-amino derivatives of tropine alkaloids |
US2948730A (en) * | 1959-02-04 | 1960-08-09 | Grace W R & Co | 8-aminotropanium compounds |
US4469700A (en) * | 1981-06-19 | 1984-09-04 | Lowell M. Somers | Benzoylecgonine or benzoylnorecgonine as active agents for the treatment of rheumatoid arthritis |
US4556663A (en) * | 1982-12-13 | 1985-12-03 | Somers Lowell M | Benzoylecgonine, benzoylnorecgonine and ecgonine as active agents for the treatment of rheumatoid arthritis and osteoarthritis |
US4512996A (en) * | 1982-12-13 | 1985-04-23 | Lowell Somers | Benzoylecgonine or benzoylnorecgonine as active agents for the treatment of rheumatoid arthritis |
FR2569563B1 (fr) * | 1984-09-03 | 1987-07-03 | Somers Lowell | Formulation a base de benzoylecgonine ou de benzoylnorecgonine pour le traitement du rhumatisme articulaire |
US5376667A (en) * | 1992-12-31 | 1994-12-27 | Entropin, Inc. | Derivatives of benzoylecgonine, ecgonine and their multiple pharmacological properties |
-
1994
- 1994-06-16 US US08/260,054 patent/US5525613A/en not_active Expired - Fee Related
-
1995
- 1995-06-07 HU HU9603443A patent/HU224634B1/hu not_active IP Right Cessation
- 1995-06-07 CA CA002190611A patent/CA2190611A1/en not_active Abandoned
- 1995-06-07 DE DE69532203T patent/DE69532203T2/de not_active Expired - Fee Related
- 1995-06-07 ES ES95923758T patent/ES2210296T3/es not_active Expired - Lifetime
- 1995-06-07 JP JP8502330A patent/JP2951409B2/ja not_active Expired - Fee Related
- 1995-06-07 DK DK95923758T patent/DK0765326T3/da active
- 1995-06-07 AT AT95923758T patent/ATE255108T1/de not_active IP Right Cessation
- 1995-06-07 EP EP95923758A patent/EP0765326B1/en not_active Expired - Lifetime
- 1995-06-07 MX MX9606374A patent/MX9606374A/es unknown
- 1995-06-07 CN CN95193632A patent/CN1046511C/zh not_active Expired - Fee Related
- 1995-06-07 WO PCT/US1995/007268 patent/WO1995034561A1/en active IP Right Grant
- 1995-06-07 NZ NZ288844A patent/NZ288844A/en unknown
- 1995-06-07 KR KR1019960707142A patent/KR100407458B1/ko not_active IP Right Cessation
- 1995-06-07 PT PT95923758T patent/PT765326E/pt unknown
- 1995-06-07 EP EP03026946A patent/EP1466913A1/en not_active Withdrawn
- 1995-06-07 AU AU28200/95A patent/AU693571B2/en not_active Ceased
- 1995-06-07 PL PL95317754A patent/PL186000B1/pl not_active IP Right Cessation
- 1995-06-15 IL IL11417795A patent/IL114177A/xx not_active IP Right Cessation
- 1995-06-15 ZA ZA955002A patent/ZA955002B/xx unknown
-
1996
- 1996-12-10 NO NO965276A patent/NO965276D0/no not_active Application Discontinuation
-
1998
- 1998-12-17 HK HK98113934A patent/HK1012626A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MX9606374A (es) | 1997-03-29 |
HU224634B1 (hu) | 2005-12-28 |
NZ288844A (en) | 1998-05-27 |
US5525613A (en) | 1996-06-11 |
EP1466913A1 (en) | 2004-10-13 |
HK1012626A1 (en) | 1999-08-06 |
PL186000B1 (pl) | 2003-09-30 |
AU693571B2 (en) | 1998-07-02 |
CN1046511C (zh) | 1999-11-17 |
DK0765326T3 (da) | 2004-04-05 |
KR100407458B1 (ko) | 2004-03-26 |
ATE255108T1 (de) | 2003-12-15 |
CA2190611A1 (en) | 1995-12-21 |
IL114177A (en) | 2000-02-17 |
HU9603443D0 (en) | 1997-02-28 |
PL317754A1 (en) | 1997-04-28 |
CN1150802A (zh) | 1997-05-28 |
JPH09510991A (ja) | 1997-11-04 |
EP0765326B1 (en) | 2003-11-26 |
NO965276L (no) | 1996-12-10 |
ES2210296T3 (es) | 2004-07-01 |
NO965276D0 (no) | 1996-12-10 |
PT765326E (pt) | 2004-03-31 |
DE69532203T2 (de) | 2004-09-09 |
DE69532203D1 (de) | 2004-01-08 |
EP0765326A1 (en) | 1997-04-02 |
AU2820095A (en) | 1996-01-05 |
ZA955002B (en) | 1996-02-08 |
IL114177A0 (en) | 1995-10-31 |
JP2951409B2 (ja) | 1999-09-20 |
WO1995034561A1 (en) | 1995-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20051019 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |