HUT71810A - Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists and pharmaceutical compositions containing them - Google Patents
Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists and pharmaceutical compositions containing themInfo
- Publication number
- HUT71810A HUT71810A HU9501842A HU9501842A HUT71810A HU T71810 A HUT71810 A HU T71810A HU 9501842 A HU9501842 A HU 9501842A HU 9501842 A HU9501842 A HU 9501842A HU T71810 A HUT71810 A HU T71810A
- Authority
- HU
- Hungary
- Prior art keywords
- fusedheterocyclic
- diaryl
- acids
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99486992A | 1992-12-22 | 1992-12-22 | |
PCT/CA1993/000541 WO1994014815A1 (en) | 1992-12-22 | 1993-12-15 | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9501842D0 HU9501842D0 (en) | 1995-08-28 |
HUT71810A true HUT71810A (en) | 1996-02-28 |
HU222274B1 HU222274B1 (hu) | 2003-05-28 |
Family
ID=25541163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9501842A HU222274B1 (hu) | 1992-12-22 | 1993-12-15 | Leukotrién antagonista hatású diaril-5,6-(kondenzált heterociklusos savak), eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0604114B1 (hu) |
KR (1) | KR100310552B1 (hu) |
CN (1) | CN1040213C (hu) |
AT (1) | ATE192448T1 (hu) |
AU (1) | AU672837B2 (hu) |
CA (1) | CA2111372C (hu) |
CZ (1) | CZ290829B6 (hu) |
DE (1) | DE69328540T2 (hu) |
DK (1) | DK0604114T3 (hu) |
ES (1) | ES2145765T3 (hu) |
FI (1) | FI111368B (hu) |
GR (1) | GR3033985T3 (hu) |
HU (1) | HU222274B1 (hu) |
IL (1) | IL108050A (hu) |
MX (1) | MX9400022A (hu) |
NO (1) | NO313831B1 (hu) |
NZ (1) | NZ258835A (hu) |
PL (1) | PL177967B1 (hu) |
PT (1) | PT604114E (hu) |
RU (1) | RU2154065C2 (hu) |
SK (1) | SK282409B6 (hu) |
WO (1) | WO1994014815A1 (hu) |
ZA (1) | ZA939560B (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5472964A (en) * | 1992-12-22 | 1995-12-05 | Merck Frosst Canada, Inc. | Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists |
US5350760A (en) * | 1993-08-04 | 1994-09-27 | Merck Frosst Canada, Inc. | Aza-5,5-fused hetrocyclic acids as leukotriene antagonists |
TW448160B (en) * | 1993-12-28 | 2001-08-01 | Merck & Co Inc | Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists |
US5427933A (en) * | 1994-07-20 | 1995-06-27 | Merck & Co., Inc. | Reduction of phenylalkyl ketones to the corresponding (S)-hydroxy derivatives using mucor hiemalis IFO 5834 |
US5491077A (en) * | 1994-07-20 | 1996-02-13 | Merck & Co., Inc. | Microbial method |
US5523477A (en) * | 1995-01-23 | 1996-06-04 | Merck & Co., Inc. | Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid |
US5750539A (en) * | 1995-06-07 | 1998-05-12 | Merck Frosst Canada | Heteroaryl diol acids as leukotriene antagonists |
JP4308667B2 (ja) * | 2002-02-06 | 2009-08-05 | デルマー ケミカルズ インコーポレーテッド | 1−(メルカプトメチル)−シクロプロパン酢酸の調製方法 |
US7271268B1 (en) | 2006-12-22 | 2007-09-18 | Formosa Laboratories Inc. | Process for preparation of [1-(mercaptomethyl)cyclopropyl]acetic acid and related derivatives |
RU2449807C2 (ru) * | 2009-11-16 | 2012-05-10 | Государственное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия федерального агентства по здравоохранению и социальному развитию" | Способ лечения эндотоксикоза при хроническом пиелонефрите |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1322005C (en) * | 1987-11-25 | 1993-09-07 | Robert N. Young | Benzoheterazoles |
ATE165088T1 (de) * | 1990-10-12 | 1998-05-15 | Merck Frosst Canada Inc | Ungesättigte hydroxyalkylchinolinsäuren als leukotrien-antagonisten |
HUT61980A (en) * | 1990-10-12 | 1993-03-29 | Merck Frosst Canada Inc | Process for producing saturated hydroxyalkylquinoline acids and pharmaceutical compositions comprising such compounds as active ingredient |
US5308850A (en) * | 1991-09-30 | 1994-05-03 | Merck Frosst Canada, Inc. | (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
-
1993
- 1993-12-14 CA CA002111372A patent/CA2111372C/en not_active Expired - Fee Related
- 1993-12-15 CZ CZ19951653A patent/CZ290829B6/cs not_active IP Right Cessation
- 1993-12-15 EP EP93310127A patent/EP0604114B1/en not_active Expired - Lifetime
- 1993-12-15 AT AT93310127T patent/ATE192448T1/de not_active IP Right Cessation
- 1993-12-15 RU RU95113598/04A patent/RU2154065C2/ru not_active IP Right Cessation
- 1993-12-15 KR KR1019950702546A patent/KR100310552B1/ko not_active IP Right Cessation
- 1993-12-15 NZ NZ258835A patent/NZ258835A/en unknown
- 1993-12-15 DE DE69328540T patent/DE69328540T2/de not_active Expired - Fee Related
- 1993-12-15 SK SK822-95A patent/SK282409B6/sk unknown
- 1993-12-15 PL PL93309408A patent/PL177967B1/pl unknown
- 1993-12-15 PT PT93310127T patent/PT604114E/pt unknown
- 1993-12-15 ES ES93310127T patent/ES2145765T3/es not_active Expired - Lifetime
- 1993-12-15 HU HU9501842A patent/HU222274B1/hu not_active IP Right Cessation
- 1993-12-15 WO PCT/CA1993/000541 patent/WO1994014815A1/en active IP Right Grant
- 1993-12-15 DK DK93310127T patent/DK0604114T3/da active
- 1993-12-16 IL IL108050A patent/IL108050A/en active IP Right Grant
- 1993-12-21 CN CN93119928A patent/CN1040213C/zh not_active Expired - Fee Related
- 1993-12-21 ZA ZA939560A patent/ZA939560B/xx unknown
- 1993-12-21 AU AU52579/93A patent/AU672837B2/en not_active Ceased
-
1994
- 1994-01-03 MX MX9400022A patent/MX9400022A/es not_active IP Right Cessation
-
1995
- 1995-06-21 NO NO19952495A patent/NO313831B1/no unknown
- 1995-06-21 FI FI953104A patent/FI111368B/fi active
-
2000
- 2000-07-19 GR GR20000401670T patent/GR3033985T3/el not_active IP Right Cessation
Also Published As
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HUT71810A (en) | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists and pharmaceutical compositions containing them | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DGB9 | Succession in title of applicant |
Owner name: MERCK FROSST CANADA & CO.,, CA |
|
HFG4 | Patent granted, date of granting |
Effective date: 20030314 |
|
HMM4 | Cancellation of final prot. due to non-payment of fee |