HUT69768A - Process for preparation of daunorubicin - Google Patents

Process for preparation of daunorubicin

Info

Publication number
HUT69768A
HUT69768A HU9302362A HU9302362A HUT69768A HU T69768 A HUT69768 A HU T69768A HU 9302362 A HU9302362 A HU 9302362A HU 9302362 A HU9302362 A HU 9302362A HU T69768 A HUT69768 A HU T69768A
Authority
HU
Hungary
Prior art keywords
daunorubicin
host
carminomycin
preparation
methyltransferase
Prior art date
Application number
HU9302362A
Other languages
English (en)
Other versions
HU9302362D0 (en
HU214354B (hu
Inventor
Francesca Torti
Anna Luisa Colombo
Charles Richard Hutchinson
Krishna Murthy Madduri
Original Assignee
Erba Carlo Spa
Hutchinson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/959,941 external-priority patent/US5364781A/en
Application filed by Erba Carlo Spa, Hutchinson filed Critical Erba Carlo Spa
Publication of HU9302362D0 publication Critical patent/HU9302362D0/hu
Publication of HUT69768A publication Critical patent/HUT69768A/hu
Publication of HU214354B publication Critical patent/HU214354B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9302362A 1991-11-18 1992-11-17 Rekombináns eljárás daunorubicin előállítására HU214354B (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79387391A 1991-11-18 1991-11-18
US07/959,941 US5364781A (en) 1991-11-18 1992-10-09 Process for preparing daunorubicin

Publications (3)

Publication Number Publication Date
HU9302362D0 HU9302362D0 (en) 1993-11-29
HUT69768A true HUT69768A (en) 1995-09-28
HU214354B HU214354B (hu) 1998-03-30

Family

ID=27121440

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9302362A HU214354B (hu) 1991-11-18 1992-11-17 Rekombináns eljárás daunorubicin előállítására

Country Status (14)

Country Link
US (1) US5563064A (hu)
EP (1) EP0567630B1 (hu)
JP (1) JP3361522B2 (hu)
AT (1) ATE192485T1 (hu)
AU (1) AU666344B2 (hu)
CA (1) CA2100334C (hu)
DE (1) DE69230997T2 (hu)
ES (1) ES2148183T3 (hu)
FI (1) FI111012B (hu)
HU (1) HU214354B (hu)
IL (1) IL103766A (hu)
MX (1) MX9206586A (hu)
NZ (1) NZ245124A (hu)
WO (1) WO1993010223A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI944556A0 (fi) * 1994-09-30 1994-09-30 Kristiina Ylihonko Foerfarande foer producering av antracykliner och deras mellanprodukter
GB2302540B (en) * 1995-06-23 1999-02-24 Pharmacia Spa Cofactor for transmethylation
US5652125A (en) * 1996-06-10 1997-07-29 Pharmacia S.P.A. Process for preparing daunorubicin
US6312920B1 (en) 1996-11-13 2001-11-06 Eli Lilly And Company SAM operon
GB2330144B (en) * 1997-03-06 2001-05-02 Pharmacia & Upjohn Spa Process for preparing doxorubicin
US5976836A (en) * 1997-05-07 1999-11-02 Fermalogic, Inc. Methods and compositions for enhancing erythromycin production
CN112080454B (zh) * 2020-09-01 2022-07-08 浙江大学 一株产柔红霉素的工程链霉菌及其构建方法
CN114457101B (zh) * 2022-01-12 2024-01-12 安徽大学 通过改造糖多孢红霉菌sace_1558基因提高红霉素产量的方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364781A (en) * 1991-11-18 1994-11-15 Farmitalia Carlo Erba S.R.L Process for preparing daunorubicin

Also Published As

Publication number Publication date
FI933200A0 (fi) 1993-07-14
MX9206586A (es) 1994-07-29
FI111012B (fi) 2003-05-15
FI933200A (fi) 1993-08-18
DE69230997T2 (de) 2000-08-17
US5563064A (en) 1996-10-08
CA2100334A1 (en) 1993-05-19
JPH06505402A (ja) 1994-06-23
EP0567630B1 (en) 2000-05-03
HU9302362D0 (en) 1993-11-29
DE69230997D1 (de) 2000-06-08
HU214354B (hu) 1998-03-30
ES2148183T3 (es) 2000-10-16
IL103766A (en) 2000-12-06
IL103766A0 (en) 1993-04-04
EP0567630A1 (en) 1993-11-03
NZ245124A (en) 1994-06-27
CA2100334C (en) 2005-05-24
AU666344B2 (en) 1996-02-08
JP3361522B2 (ja) 2003-01-07
AU3129093A (en) 1993-06-15
WO1993010223A1 (en) 1993-05-27
ATE192485T1 (de) 2000-05-15

Similar Documents

Publication Publication Date Title
HK1013847A1 (en) Gdf-1 and uog-1 proteins
DK1025211T3 (da) Hyaluronansyntasegen og anvendelser deraf
ES8609475A1 (es) Procedimiento para preparar peptidos de interferon
HUT69768A (en) Process for preparation of daunorubicin
AU577810B2 (en) Cloning the gene for rabbit tumor necrosis factor polypeptide
AU7247891A (en) Purified myeloblastin, nucleic acid molecule encoding same, and uses thereof
EP0785716A4 (en) CYTOKINE CALLED LERK-6
AU4569293A (en) Anti-feline immunodeficiency virus (fiv) vaccines
AU6181494A (en) DNA fragment, vector containing the DNA fragment, transformant transformed with the vector and process for producing protein using the vector
WO1999055829A3 (en) Process for preparing doxorubicin
GB9203821D0 (en) Improvements in or relating to malaria vaccine
IL90386A0 (en) Dna according anthracycline resistance,its preparation and vectors and host microorganism containing it
EP0220714A3 (en) Dna fragment containing the cyclodextrin-glycosyl-transferase gene, expression vector, microorganisms for expression and preparation process
AU2043597A (en) Human taki dna encoding the same
TW342413B (en) Novel toxins isolated from Bracon Hebetor
WO1997035993A3 (en) PSA positive regulating (PSAR) sequences and uses thereof
AU8132994A (en) Nucleic acids encoding {his5, trp7, tyr8}-gnrh preprohormone and {ser8}-gnrh preprohormone and their uses
Lo Christmas, 1990
EP0183272A3 (en) Vector capable of efficient gene expression and utilization of such vector
MX9605018A (es) Proceso para la preparacion de doxorrubicina.
Patterson III Tombs of Science
Giese Prisms

Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees