HUT62278A - Process for producing piperazine derivatives - Google Patents

Process for producing piperazine derivatives

Info

Publication number
HUT62278A
HUT62278A HU906953A HU695390A HUT62278A HU T62278 A HUT62278 A HU T62278A HU 906953 A HU906953 A HU 906953A HU 695390 A HU695390 A HU 695390A HU T62278 A HUT62278 A HU T62278A
Authority
HU
Hungary
Prior art keywords
piperazine derivatives
producing piperazine
producing
derivatives
piperazine
Prior art date
Application number
HU906953A
Other languages
English (en)
Other versions
HU906953D0 (en
HU209723B (en
Inventor
Csongor Eva Againe
Tibor Gizur
Kalman Harsanyi
Ferenc Trischler
Laszlone Demeter
Attila Csehi
Eva Vajda
Komlosi Gyoergyi Szabone
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU906953A priority Critical patent/HU209723B/hu
Publication of HU906953D0 publication Critical patent/HU906953D0/hu
Priority to PT99368A priority patent/PT99368A/pt
Priority to CA002054544A priority patent/CA2054544A1/en
Priority to AU86830/91A priority patent/AU8683091A/en
Priority to NO91914250A priority patent/NO914250L/no
Priority to JP3285053A priority patent/JPH04264078A/ja
Priority to KR1019910019180A priority patent/KR920008018A/ko
Priority to PL29222791A priority patent/PL292227A1/xx
Priority to ZA918636A priority patent/ZA918636B/xx
Priority to CS913294A priority patent/CS329491A3/cs
Priority to EP91202836A priority patent/EP0483932A1/en
Publication of HUT62278A publication Critical patent/HUT62278A/hu
Publication of HU209723B publication Critical patent/HU209723B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU906953A 1990-10-31 1990-10-31 Process for producing of piperazine derivatives HU209723B (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
HU906953A HU209723B (en) 1990-10-31 1990-10-31 Process for producing of piperazine derivatives
PT99368A PT99368A (pt) 1990-10-31 1991-10-29 Processo para a preparacao de derivados de piperazina
CS913294A CS329491A3 (en) 1990-10-31 1991-10-30 Process for preparing piperazine derivatives
NO91914250A NO914250L (no) 1990-10-31 1991-10-30 Fremgangsmaate for fremstilling av piperazinderivater
AU86830/91A AU8683091A (en) 1990-10-31 1991-10-30 Process for the preparation of piperazine derivatives
CA002054544A CA2054544A1 (en) 1990-10-31 1991-10-30 Process for the preparation of piperazine derivatives
JP3285053A JPH04264078A (ja) 1990-10-31 1991-10-30 ピペラジン誘導体の製造方法
KR1019910019180A KR920008018A (ko) 1990-10-31 1991-10-30 피페라진 유도체의 제조방법
PL29222791A PL292227A1 (en) 1990-10-31 1991-10-30 Method of obtaining piperazine derivatives
ZA918636A ZA918636B (en) 1990-10-31 1991-10-30 Process for the preparation of piperazine derivatives
EP91202836A EP0483932A1 (en) 1990-10-31 1991-10-31 Process for the preparation of piperazine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU906953A HU209723B (en) 1990-10-31 1990-10-31 Process for producing of piperazine derivatives

Publications (3)

Publication Number Publication Date
HU906953D0 HU906953D0 (en) 1991-05-28
HUT62278A true HUT62278A (en) 1993-04-28
HU209723B HU209723B (en) 1994-10-28

Family

ID=10972063

Family Applications (1)

Application Number Title Priority Date Filing Date
HU906953A HU209723B (en) 1990-10-31 1990-10-31 Process for producing of piperazine derivatives

Country Status (11)

Country Link
EP (1) EP0483932A1 (hu)
JP (1) JPH04264078A (hu)
KR (1) KR920008018A (hu)
AU (1) AU8683091A (hu)
CA (1) CA2054544A1 (hu)
CS (1) CS329491A3 (hu)
HU (1) HU209723B (hu)
NO (1) NO914250L (hu)
PL (1) PL292227A1 (hu)
PT (1) PT99368A (hu)
ZA (1) ZA918636B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0585500A1 (en) * 1992-09-04 1994-03-09 Merrell Dow Pharmaceuticals Inc. Diaryl piperazineacetamides as antimuscarinic agents
WO2001062749A1 (en) 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Substituted piperazine compounds
WO2001062711A2 (en) 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Substituted alkylene diamine compounds
US6677336B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
MXPA02008213A (es) * 2000-02-22 2004-04-05 Cv Therapeutics Inc Compuestos piperazina sustituidos.
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
KR100797835B1 (ko) * 2001-08-13 2008-01-24 주식회사 포스코 핀치롤의 이물질 제거장치
WO2004063180A1 (en) 2003-01-03 2004-07-29 Cv Therapeutics, Inc. Substituted heterocyclic compounds
CA2530376A1 (en) 2003-06-23 2005-01-06 Cv Therapeutics, Inc. Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
EP1723129A1 (en) * 2003-12-18 2006-11-22 Cv Therapeutics, Inc. 1-akan-2-ol substituted piperazine and piperidine compounds
WO2006008753A1 (en) * 2004-07-19 2006-01-26 Unichem Laboratories Limited Crystalline and amorphous form of ranolazine and the process for manufacturing them
WO2008047388A2 (en) * 2006-10-20 2008-04-24 Ind-Swift Laboratories Limited Improved process for the preparation of ranolazine
WO2008139492A2 (en) * 2007-05-15 2008-11-20 Natco Pharma Limited A process for the preparation of highly pure ranolazine base
US20110300218A1 (en) * 2008-09-09 2011-12-08 Actavis Group Ptc Ehf Novel solid state forms of ranolazine salts
US20110223213A1 (en) * 2008-10-15 2011-09-15 Actavis Group Ptc Ehf Highly pure ranolazine or a pharmaceutically acceptable salt thereof
WO2010097805A1 (en) 2009-02-24 2010-09-02 Lupin Limited A process for the preparation of ranolazine
WO2016142819A2 (en) 2015-03-10 2016-09-15 Unichem Laboratories Limited Novel process for the preparation of ranolazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB662283A (en) * 1948-08-02 1951-12-05 Rhone Poulenc Sa Improvements in or relating to piperazine compounds
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry

Also Published As

Publication number Publication date
HU906953D0 (en) 1991-05-28
CA2054544A1 (en) 1992-05-01
NO914250D0 (no) 1991-10-30
NO914250L (no) 1992-05-04
AU8683091A (en) 1992-05-07
CS329491A3 (en) 1992-05-13
JPH04264078A (ja) 1992-09-18
HU209723B (en) 1994-10-28
PL292227A1 (en) 1992-06-26
PT99368A (pt) 1992-09-30
ZA918636B (en) 1992-08-26
KR920008018A (ko) 1992-05-27
EP0483932A1 (en) 1992-05-06

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee