HUT56363A - Process for producing 8-alpha-acylaminoergoline derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing 8-alpha-acylaminoergoline derivatives and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT56363A
HUT56363A HU904426A HU442690A HUT56363A HU T56363 A HUT56363 A HU T56363A HU 904426 A HU904426 A HU 904426A HU 442690 A HU442690 A HU 442690A HU T56363 A HUT56363 A HU T56363A
Authority
HU
Hungary
Prior art keywords
alpha
acylaminoergoline
derivatives
compounds
producing
Prior art date
Application number
HU904426A
Other languages
English (en)
Other versions
HU212814B (hu
HU904426D0 (en
Inventor
Gerhard Sauer
Thomas Brumby
Jonathan Turner
Peter Andreas Loeschmann
Helmut Wachtel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of HU904426D0 publication Critical patent/HU904426D0/hu
Publication of HUT56363A publication Critical patent/HUT56363A/hu
Publication of HU212814B publication Critical patent/HU212814B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU904426A 1989-05-12 1990-05-10 Eljárás 8-alfa-(acil-amino)-ergolin-származékok és hatóanyagként ezeket tartalmazó gyógyszerkészítmények előállítására HU212814B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3915950A DE3915950A1 (de) 1989-05-12 1989-05-12 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
HU904426D0 HU904426D0 (en) 1991-07-29
HUT56363A true HUT56363A (en) 1991-08-28
HU212814B HU212814B (hu) 1998-08-28

Family

ID=6380759

Family Applications (1)

Application Number Title Priority Date Filing Date
HU904426A HU212814B (hu) 1989-05-12 1990-05-10 Eljárás 8-alfa-(acil-amino)-ergolin-származékok és hatóanyagként ezeket tartalmazó gyógyszerkészítmények előállítására

Country Status (14)

Country Link
US (2) US5212178A (hu)
EP (1) EP0427827B1 (hu)
JP (1) JPH04500681A (hu)
AT (1) ATE147742T1 (hu)
CA (1) CA2028832A1 (hu)
CZ (2) CZ279080B6 (hu)
DD (1) DD294259A5 (hu)
DE (2) DE3915950A1 (hu)
DK (1) DK0427827T3 (hu)
ES (1) ES2098263T3 (hu)
HU (1) HU212814B (hu)
PT (1) PT94011B (hu)
SK (2) SK277997B6 (hu)
WO (1) WO1990013550A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6018332A (en) * 1997-11-21 2000-01-25 Ark Interface Ii, Inc. Overscan user interface
US8113807B2 (en) * 2007-08-24 2012-02-14 Timothy Wilkinson Methods and apparatus for fabricating structures
WO2013095707A1 (en) * 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
WO1982000463A1 (en) * 1980-07-25 1982-02-18 Ag Sandoz Ergoline derivatives,method for their preparation,pharmaceutical compositions containing them and their therapeutic application
DE3135305C2 (de) * 1981-09-03 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
NL8400333A (nl) * 1983-02-16 1984-09-17 Sandoz Ag Moederkoornalkaloiden, hun bereiding en hun toepassing.
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DE3544365A1 (de) * 1984-12-24 1986-07-03 Sandoz-Patent-GmbH, 7850 Lörrach 8(alpha)-acylaminoergoline
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
DE3528584A1 (de) * 1985-08-06 1987-02-19 Schering Ag Neue 1-alkyl-ergolin-thioharnstoffderivate
DE3700825A1 (de) * 1986-01-24 1987-07-30 Sandoz Ag 8(alpha)-acylaminoergoline, ihre herstellung und verwendung
HUT45248A (en) * 1986-01-24 1988-06-28 Sandoz Ag Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3708028A1 (de) * 1987-03-10 1988-09-22 Schering Ag Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
HU212814B (hu) 1998-08-28
CZ260491A3 (en) 1993-03-17
SK260491A3 (en) 1995-09-13
DK0427827T3 (da) 1997-07-07
CA2028832A1 (en) 1990-11-13
SK233190A3 (en) 1995-09-13
PT94011B (pt) 1996-12-31
CZ278981B6 (en) 1994-11-16
PT94011A (pt) 1991-01-08
DE3915950A1 (de) 1990-11-15
SK277996B6 (en) 1995-09-13
WO1990013550A1 (de) 1990-11-15
SK277997B6 (en) 1995-09-13
JPH04500681A (ja) 1992-02-06
EP0427827B1 (de) 1997-01-15
US5212178A (en) 1993-05-18
EP0427827A1 (de) 1991-05-22
ES2098263T3 (es) 1997-05-01
DD294259A5 (de) 1991-09-26
DE59010633D1 (de) 1997-03-06
CZ279080B6 (en) 1994-12-15
ATE147742T1 (de) 1997-02-15
US5547958A (en) 1996-08-20
HU904426D0 (en) 1991-07-29
CZ233190A3 (en) 1994-02-16

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee