HUT56089A - Process for producing quinazoline derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing quinazoline derivatives and pharmaceutical compositions containing them

Info

Publication number
HUT56089A
HUT56089A HU917A HU791A HUT56089A HU T56089 A HUT56089 A HU T56089A HU 917 A HU917 A HU 917A HU 791 A HU791 A HU 791A HU T56089 A HUT56089 A HU T56089A
Authority
HU
Hungary
Prior art keywords
alkyl
hydroxy
protected
pharmaceutical compositions
compositions containing
Prior art date
Application number
HU917A
Other languages
English (en)
Other versions
HU208131B (en
Inventor
Norihiko Shimazaki
Hitoshi Yamazaki
Takumi Yatabe
Hirokazu Tanaka
Yoshikuni Itoh
Masashi Hashimoto
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909000014A external-priority patent/GB9000014D0/en
Priority claimed from GB909025065A external-priority patent/GB9025065D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of HUT56089A publication Critical patent/HUT56089A/hu
Publication of HU208131B publication Critical patent/HU208131B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU917A 1990-01-02 1991-01-02 Process for producing quinezoline derivatives and pharmaceutical compositions comprising same HU208131B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909000014A GB9000014D0 (en) 1990-01-02 1990-01-02 Quinazoline derivatives and their preparation
GB909025065A GB9025065D0 (en) 1990-11-19 1990-11-19 Quinazoline derivatives and their preparation

Publications (2)

Publication Number Publication Date
HUT56089A true HUT56089A (en) 1991-07-29
HU208131B HU208131B (en) 1993-08-30

Family

ID=26296447

Family Applications (1)

Application Number Title Priority Date Filing Date
HU917A HU208131B (en) 1990-01-02 1991-01-02 Process for producing quinezoline derivatives and pharmaceutical compositions comprising same

Country Status (14)

Country Link
US (1) US5264438A (hu)
EP (1) EP0436157B1 (hu)
JP (1) JPH0578349A (hu)
KR (1) KR910014368A (hu)
CN (1) CN1053063A (hu)
AT (1) ATE126796T1 (hu)
AU (1) AU635099B2 (hu)
CA (1) CA2033363A1 (hu)
DE (1) DE69021855T2 (hu)
FI (1) FI906425L (hu)
HU (1) HU208131B (hu)
IE (1) IE904580A1 (hu)
NO (1) NO905620L (hu)
PT (1) PT96404A (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202318A (en) * 1990-05-14 1993-04-13 Syntex (U.S.A.) Inc. Tricyclic compounds acting at serotonin receptor subtypes
CA2117075A1 (en) * 1991-09-06 1993-03-18 Norihiko Shimazaki Quinazoline derivatives and their preparation
GB9127532D0 (en) * 1991-12-31 1992-02-19 Fujisawa Pharmaceutical Co A novel use of a quinazoline derivative
GB9205702D0 (en) * 1992-03-16 1992-04-29 Fujisawa Pharmaceutical Co A new use of a quinazoline derivative
FR2723091B1 (fr) * 1994-07-29 1996-11-08 Esteve Labor Dr Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
WO1997029079A1 (en) * 1996-02-06 1997-08-14 Japan Tobacco Inc. Novel compounds and pharmaceutical use thereof
AU5679398A (en) * 1997-01-31 1998-08-25 Kyowa Hakko Kogyo Co. Ltd. Piperidine derivatives
US6521630B1 (en) 1999-08-31 2003-02-18 Pfizer Inc. Tetrahydroquinazoline-2,4-diones and therapeutic uses thereof
DE102004020908A1 (de) * 2004-04-28 2005-11-17 Grünenthal GmbH Substituierte 5,6,7,8,-Tetrahydro-pyrido[4,3-d]pyrimidin-2-yl- und 5,6,7,8,-Tetrahydro-chinazolin-2-yl-Verbindungen
EP1954689A4 (en) * 2005-09-15 2009-09-02 Korea Res Inst Chem Tech N-SUBSTITUTED 1H-CHINOLIN-2,4-DIONE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF
JP2009542628A (ja) * 2006-07-05 2009-12-03 コーリア リサーチ インスティテュート オブ ケミカル テクノロジー 新規な置換−１ｈ−キナゾリン−２，４−ジオン誘導体、その製造方法及びそれを含む薬学的組成物
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
CN103739596A (zh) * 2013-12-10 2014-04-23 刘磊 用于心脑血管疾病的喹唑啉衍生物
CN106146413B (zh) * 2015-04-03 2019-01-18 中南大学 2,4-(1h,3h)-喹唑啉二酮衍生物及其合成方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274194A (en) * 1963-03-29 1966-09-20 Miles Lab Quinazolinedione derivatives
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation

Also Published As

Publication number Publication date
PT96404A (pt) 1991-10-15
US5264438A (en) 1993-11-23
ATE126796T1 (de) 1995-09-15
IE904580A1 (en) 1991-07-03
NO905620L (no) 1991-07-03
HU208131B (en) 1993-08-30
EP0436157A1 (en) 1991-07-10
DE69021855D1 (de) 1995-09-28
AU635099B2 (en) 1993-03-11
KR910014368A (ko) 1991-08-31
FI906425A7 (fi) 1991-07-03
CA2033363A1 (en) 1991-07-03
AU6820790A (en) 1991-07-04
JPH0578349A (ja) 1993-03-30
CN1053063A (zh) 1991-07-17
NO905620D0 (no) 1990-12-28
FI906425A0 (fi) 1990-12-28
FI906425L (fi) 1991-07-03
DE69021855T2 (de) 1996-02-29
EP0436157B1 (en) 1995-08-23

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee