HUT50767A - Process for producing new 1,3,4,5-tetrahydro-benz/c,d/indole derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing new 1,3,4,5-tetrahydro-benz/c,d/indole derivatives and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT50767A
HUT50767A HU891258A HU125889A HUT50767A HU T50767 A HUT50767 A HU T50767A HU 891258 A HU891258 A HU 891258A HU 125889 A HU125889 A HU 125889A HU T50767 A HUT50767 A HU T50767A
Authority
HU
Hungary
Prior art keywords
compounds
benz
tetrahydro
pharmaceutical compositions
indole derivatives
Prior art date
Application number
HU891258A
Other languages
English (en)
Other versions
HU204034B (en
Inventor
Bodo Junge
Bernd Richter
Thomas Glaser
Joerg Traber
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HUT50767A publication Critical patent/HUT50767A/hu
Publication of HU204034B publication Critical patent/HU204034B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
HU891258A 1988-03-18 1989-03-17 Process for producing new 1,3,4,5-tetrahydrobenz(c,d)indole derivatives and pharmaceutical compositions comprising such compounds HU204034B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809155A DE3809155A1 (de) 1988-03-18 1988-03-18 1,3,4,5-tetrahydrobenz-(c,d)-indole

Publications (2)

Publication Number Publication Date
HUT50767A true HUT50767A (en) 1990-03-28
HU204034B HU204034B (en) 1991-11-28

Family

ID=6350115

Family Applications (1)

Application Number Title Priority Date Filing Date
HU891258A HU204034B (en) 1988-03-18 1989-03-17 Process for producing new 1,3,4,5-tetrahydrobenz(c,d)indole derivatives and pharmaceutical compositions comprising such compounds

Country Status (18)

Country Link
US (1) US5021438A (hu)
EP (1) EP0332968B1 (hu)
JP (1) JPH02204479A (hu)
KR (1) KR890014474A (hu)
CN (1) CN1036566A (hu)
AT (1) ATE90093T1 (hu)
AU (1) AU614343B2 (hu)
DD (1) DD283606A5 (hu)
DE (2) DE3809155A1 (hu)
DK (1) DK131789A (hu)
ES (1) ES2058365T3 (hu)
FI (1) FI891252A (hu)
HU (1) HU204034B (hu)
IL (1) IL89623A (hu)
NO (1) NO890892L (hu)
NZ (1) NZ228341A (hu)
PT (1) PT90012B (hu)
ZA (1) ZA892049B (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3826371A1 (de) * 1988-08-03 1990-02-08 Bayer Ag Tetrahydro-1-benz-(c,d)-indolpropionsaeure-sulfonamide
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5212319A (en) * 1990-02-26 1993-05-18 Eli Lilly And Company Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
TW219933B (hu) * 1990-02-26 1994-02-01 Lilly Co Eli
US5264442A (en) * 1990-08-13 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
ES2079532T3 (es) * 1990-08-13 1996-01-16 Hoechst Roussel Pharma Carbamoil-1-(piridinilalquil)-1h-indoles, indolinas y analogos relacionados.
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5643934A (en) * 1991-03-28 1997-07-01 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles
IL109872A (en) * 1993-06-10 2000-12-06 Lilly Co Eli Tetrahydrobenz ¬CD¾ indole-6-carboxamides for use in preventing emesis and pharmaceutical compositions comprising same
TW430660B (en) * 1996-05-30 2001-04-21 Mochida Pharm Co Ltd Novel benzindole derivatives for neuron cell protection, processes for production, and the pharmaceutical compounds containing them
US6723730B2 (en) * 2000-07-20 2004-04-20 Neurogen Corporation Capsaicin receptor ligands
WO2020176597A1 (en) 2019-02-27 2020-09-03 The Regents Of The University Of California N-substituted indoles and other heterocycles for treating brain disorders
SG11202109111VA (en) 2019-02-27 2021-09-29 Univ California Azepino-indoles and other heterocycles for treating brain disorders
US20230295106A1 (en) * 2019-10-14 2023-09-21 The Regents Of The University Of California Ergoline-like compounds for promoting neural plasticity
CN115584206A (zh) * 2022-10-13 2023-01-10 吕辉 一种水性无机纳米陶瓷阻燃涂料及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE542760A (hu) * 1954-11-12
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles
FR2471373A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux derives de la benzindolamine, leurs sels, procede de preparation, application a titre de medicaments et composition les renfermant
DE3346513A1 (de) 1983-12-22 1985-07-11 Süddeutsche Kühlerfabrik Julius Fr. Behr GmbH & Co. KG, 7000 Stuttgart Vorrichtung zum erwaermen von wasser
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
DE3718892A1 (de) * 1987-06-05 1988-12-22 Bayer Ag Polyhydrobenz(c,d)indol-sulfonamide

Also Published As

Publication number Publication date
KR890014474A (ko) 1989-10-23
DD283606A5 (de) 1990-10-17
NO890892D0 (no) 1989-03-02
FI891252A0 (fi) 1989-03-16
ATE90093T1 (de) 1993-06-15
PT90012A (pt) 1989-11-10
DK131789D0 (da) 1989-03-17
HU204034B (en) 1991-11-28
PT90012B (pt) 1994-06-30
EP0332968B1 (de) 1993-06-02
IL89623A0 (en) 1989-09-10
AU614343B2 (en) 1991-08-29
AU3152689A (en) 1989-09-28
EP0332968A1 (de) 1989-09-20
JPH02204479A (ja) 1990-08-14
IL89623A (en) 1993-01-14
DE3809155A1 (de) 1989-09-28
ZA892049B (en) 1989-11-29
DE58904539D1 (de) 1993-07-08
NZ228341A (en) 1990-12-21
US5021438A (en) 1991-06-04
DK131789A (da) 1989-09-19
CN1036566A (zh) 1989-10-25
ES2058365T3 (es) 1994-11-01
FI891252A (fi) 1989-09-19
NO890892L (no) 1989-09-19

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee