HUT47251A - Process for producing pyridine-2,4- and -2,5-dicarboxylic acid derivatives and pharmaceuticals comprising such compounds - Google Patents

Process for producing pyridine-2,4- and -2,5-dicarboxylic acid derivatives and pharmaceuticals comprising such compounds

Info

Publication number
HUT47251A
HUT47251A HU88611A HU61188A HUT47251A HU T47251 A HUT47251 A HU T47251A HU 88611 A HU88611 A HU 88611A HU 61188 A HU61188 A HU 61188A HU T47251 A HUT47251 A HU T47251A
Authority
HU
Hungary
Prior art keywords
compounds
dicarboxylic acid
acid derivatives
pharmaceuticals
producing pyridine
Prior art date
Application number
HU88611A
Other languages
English (en)
Other versions
HU199801B (en
Inventor
Dietrich Brocks
Harald Burghard
Volkmar Guenzler
Hartmut Hanauske-Abel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HUT47251A publication Critical patent/HUT47251A/hu
Publication of HU199801B publication Critical patent/HU199801B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
HU88611A 1987-02-10 1988-02-10 Process for producing pyridine-2,4- and -2,5-dicarboxylic acid derivatives and pharmaceutical compositions comprising such compounds HU199801B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873703962 DE3703962A1 (de) 1987-02-10 1987-02-10 Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen

Publications (2)

Publication Number Publication Date
HUT47251A true HUT47251A (en) 1989-02-28
HU199801B HU199801B (en) 1990-03-28

Family

ID=6320592

Family Applications (1)

Application Number Title Priority Date Filing Date
HU88611A HU199801B (en) 1987-02-10 1988-02-10 Process for producing pyridine-2,4- and -2,5-dicarboxylic acid derivatives and pharmaceutical compositions comprising such compounds

Country Status (20)

Country Link
US (1) US4968670A (hu)
EP (1) EP0278454B1 (hu)
JP (1) JPS63216871A (hu)
KR (1) KR960004861B1 (hu)
AT (1) ATE85048T1 (hu)
AU (1) AU604293B2 (hu)
CA (1) CA1315471C (hu)
DE (2) DE3703962A1 (hu)
DK (1) DK168008B1 (hu)
ES (1) ES2046218T3 (hu)
FI (1) FI90767C (hu)
GR (1) GR3007607T3 (hu)
HU (1) HU199801B (hu)
IE (1) IE62353B1 (hu)
IL (1) IL85360A0 (hu)
NO (1) NO174852C (hu)
NZ (1) NZ223432A (hu)
PH (1) PH24512A (hu)
PT (1) PT86735B (hu)
ZA (1) ZA88895B (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
US5425289A (en) * 1993-10-21 1995-06-20 Snap-On Incorporated Bung tool
DE3924093A1 (de) * 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3938805A1 (de) * 1989-11-23 1991-05-29 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4031000A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
EP0548883A1 (de) * 1991-12-24 1993-06-30 Hoechst Aktiengesellschaft Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals
DE4233124A1 (de) * 1992-10-02 1994-04-07 Hoechst Ag Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2308551C (en) * 1997-10-24 2010-02-16 Fibrogen, Inc. Phenanthroline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
ATE113036T1 (de) * 1988-08-04 1994-11-15 Hoechst Ag Verbessertes verfahren zur herstellung von n,n- bis(alkoxyalkyl)-pyridin -2,4- dicarbonsäurediamiden.

Also Published As

Publication number Publication date
NO880557D0 (no) 1988-02-09
FI90767B (fi) 1993-12-15
PT86735B (pt) 1992-05-29
JPS63216871A (ja) 1988-09-09
GR3007607T3 (hu) 1993-08-31
DK168008B1 (da) 1994-01-17
DE3877778D1 (de) 1993-03-11
EP0278454A2 (de) 1988-08-17
EP0278454B1 (de) 1993-01-27
NZ223432A (en) 1990-04-26
DK66188D0 (da) 1988-02-09
FI880555A0 (fi) 1988-02-08
PH24512A (en) 1990-07-18
NO174852C (no) 1994-07-20
DE3703962A1 (de) 1988-08-18
KR880009934A (ko) 1988-10-05
AU604293B2 (en) 1990-12-13
NO880557L (no) 1988-08-11
HU199801B (en) 1990-03-28
DK66188A (da) 1988-08-11
US4968670A (en) 1990-11-06
AU1145188A (en) 1988-08-11
IE62353B1 (en) 1995-01-25
ZA88895B (en) 1988-08-08
ATE85048T1 (de) 1993-02-15
EP0278454A3 (en) 1989-10-18
CA1315471C (en) 1993-03-30
KR960004861B1 (en) 1996-04-16
PT86735A (pt) 1988-03-01
FI880555A (fi) 1988-08-11
IE880351L (en) 1988-08-10
FI90767C (fi) 1994-03-25
NO174852B (no) 1994-04-11
IL85360A0 (en) 1988-07-31
ES2046218T3 (es) 1994-02-01

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee