HUT46312A - Process for producing 1-alkyl-4-oxo-1,4-dihydro-quinoline-carboxylic acids
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Process for producing 1-alkyl-4-oxo-1,4-dihydro-quinoline-carboxylic acids
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Publication number
HUT46312A
HUT46312AHU145887AHU145887AHUT46312AHU T46312 AHUT46312 AHU T46312AHU 145887 AHU145887 AHU 145887AHU 145887 AHU145887 AHU 145887AHU T46312 AHUT46312 AHU T46312A
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Application filed by Chinoin Gyogyszer Es VegyeszetfiledCriticalChinoin Gyogyszer Es Vegyeszet
Priority to HU145887ApriorityCriticalpatent/HU196965B/en
Publication of HUT46312ApublicationCriticalpatent/HUT46312A/en
Publication of HU196965BpublicationCriticalpatent/HU196965B/en
Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Quinoline Compounds
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
1-alkyl-4-oxo- 1,4-di:hydro-quinoliNe carboxylic-acid-ester of formula (I) where R = R1 = 1-4C alkyl gps. R2,R3,R4 may be identical or different gps. of hydrogen or halogen atoms, but at least one substituent should be other than hydrogen, is prepd. by N-alkylating a quinoline-3-carboxylic acid ester of formula (II), - where R1,R2,R3 and R4 as above - with a tri-alkyl-phosphate (RO)3PO (III) - where R = 1-4C alkyl gp. - in the presence of an acid scavenger and at 10-280 deg.C.
HU145887A1987-04-061987-04-06New process for producing esters of 1-alkyl-4-oxo-1,4-dihydro-quinoline-carboxylic acids
HU196965B
(en)