HUT44041A - Process for producing new diamino-androstane derivatives - Google Patents

Process for producing new diamino-androstane derivatives

Info

Publication number
HUT44041A
HUT44041A HU852553A HU255385A HUT44041A HU T44041 A HUT44041 A HU T44041A HU 852553 A HU852553 A HU 852553A HU 255385 A HU255385 A HU 255385A HU T44041 A HUT44041 A HU T44041A
Authority
HU
Hungary
Prior art keywords
producing new
androstane derivatives
new diamino
diamino
chem
Prior art date
Application number
HU852553A
Other languages
English (en)
Other versions
HU195972B (en
Inventor
Zoltan Tuba
Marsai Maria Lovasne
Katalin Biro
Egon Karpaty
Judit Horvath
Miklos Riesz
Laszlo Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU852553A priority Critical patent/HU195972B/hu
Priority to IL79211A priority patent/IL79211A0/xx
Priority to US06/879,805 priority patent/US5410040A/en
Priority to CA000512721A priority patent/CA1314868C/en
Priority to AU59363/86A priority patent/AU586691B2/en
Priority to JP61151844A priority patent/JPS625992A/ja
Priority to DE8989108244T priority patent/DE3688559T2/de
Priority to AT86305079T priority patent/ATE61374T1/de
Priority to EP86305079A priority patent/EP0208497B1/en
Priority to AT89108244T priority patent/ATE90358T1/de
Priority to EP89108244A priority patent/EP0345471B1/en
Priority to DE8686305079T priority patent/DE3677841D1/de
Publication of HUT44041A publication Critical patent/HUT44041A/hu
Publication of HU195972B publication Critical patent/HU195972B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
HU852553A 1985-07-01 1985-07-01 Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them HU195972B (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
HU852553A HU195972B (en) 1985-07-01 1985-07-01 Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
IL79211A IL79211A0 (en) 1985-07-01 1986-06-24 Diamino-androstane derivatives,process for their preparation and pharmaceutical compositions containing them
US06/879,805 US5410040A (en) 1985-07-01 1986-06-27 Diamino-androstane derivatives
CA000512721A CA1314868C (en) 1985-07-01 1986-06-27 Diamino-androstane derivatives, process for their preparation and pharmaceutical compositions containing them
AU59363/86A AU586691B2 (en) 1985-07-01 1986-06-30 Diamino-androstane derivatives, process for their preparation and pharmaceutical compositions containing them
JP61151844A JPS625992A (ja) 1985-07-01 1986-06-30 ジアミノ−アンドロスタン誘導体，その製造方法およびその誘導体を含有する医薬組成物
DE8989108244T DE3688559T2 (de) 1985-07-01 1986-07-01 Zwischenprodukte in der synthese von diaminandrostan-derivaten.
AT86305079T ATE61374T1 (de) 1985-07-01 1986-07-01 Diaminoandrostanderivate.
EP86305079A EP0208497B1 (en) 1985-07-01 1986-07-01 Diamino-androstane derivatives
AT89108244T ATE90358T1 (de) 1985-07-01 1986-07-01 Zwischenprodukte in der synthese von diaminandrostan-derivaten.
EP89108244A EP0345471B1 (en) 1985-07-01 1986-07-01 Intermediates in the synthesis of diamino-androstane derivatives
DE8686305079T DE3677841D1 (de) 1985-07-01 1986-07-01 Diaminoandrostanderivate.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852553A HU195972B (en) 1985-07-01 1985-07-01 Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
HUT44041A true HUT44041A (en) 1988-01-28
HU195972B HU195972B (en) 1988-08-29

Family

ID=10959960

Family Applications (1)

Application Number Title Priority Date Filing Date
HU852553A HU195972B (en) 1985-07-01 1985-07-01 Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them

Country Status (9)

Country Link
US (1) US5410040A (hu)
EP (2) EP0345471B1 (hu)
JP (1) JPS625992A (hu)
AT (2) ATE61374T1 (hu)
AU (1) AU586691B2 (hu)
CA (1) CA1314868C (hu)
DE (2) DE3688559T2 (hu)
HU (1) HU195972B (hu)
IL (1) IL79211A0 (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
US5588152A (en) 1990-11-13 1996-12-24 International Business Machines Corporation Advanced parallel processor including advanced support hardware
US5765011A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Parallel processing system having a synchronous SIMD processing with processing elements emulating SIMD operation using individual instruction streams
US5815723A (en) 1990-11-13 1998-09-29 International Business Machines Corporation Picket autonomy on a SIMD machine
US5630162A (en) 1990-11-13 1997-05-13 International Business Machines Corporation Array processor dotted communication network based on H-DOTs
US5617577A (en) 1990-11-13 1997-04-01 International Business Machines Corporation Advanced parallel array processor I/O connection
US5734921A (en) 1990-11-13 1998-03-31 International Business Machines Corporation Advanced parallel array processor computer package
US5590345A (en) 1990-11-13 1996-12-31 International Business Machines Corporation Advanced parallel array processor(APAP)
US5794059A (en) 1990-11-13 1998-08-11 International Business Machines Corporation N-dimensional modified hypercube
DE69131272T2 (de) 1990-11-13 1999-12-09 International Business Machines Corp., Armonk Paralleles Assoziativprozessor-System
US5966528A (en) 1990-11-13 1999-10-12 International Business Machines Corporation SIMD/MIMD array processor with vector processing
US5752067A (en) 1990-11-13 1998-05-12 International Business Machines Corporation Fully scalable parallel processing system having asynchronous SIMD processing
US5765012A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Controller for a SIMD/MIMD array having an instruction sequencer utilizing a canned routine library
US5963746A (en) 1990-11-13 1999-10-05 International Business Machines Corporation Fully distributed processing memory element
US5765015A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Slide network for an array processor
US5963745A (en) 1990-11-13 1999-10-05 International Business Machines Corporation APAP I/O programmable router
US5809292A (en) 1990-11-13 1998-09-15 International Business Machines Corporation Floating point for simid array machine
US5828894A (en) 1990-11-13 1998-10-27 International Business Machines Corporation Array processor having grouping of SIMD pickets
US5625836A (en) 1990-11-13 1997-04-29 International Business Machines Corporation SIMD/MIMD processing memory element (PME)
US5594918A (en) 1991-05-13 1997-01-14 International Business Machines Corporation Parallel computer system providing multi-ported intelligent memory
JP2642039B2 (ja) 1992-05-22 1997-08-20 インターナショナル・ビジネス・マシーンズ・コーポレイション アレイ・プロセッサ
HU212459B (en) * 1992-10-02 1996-06-28 Richter Gedeon Vegyeszet Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
US9820718B2 (en) 2012-03-01 2017-11-21 Syracuse University Enhanced electronic external fetal monitoring system
WO2022241404A1 (en) * 2021-05-11 2022-11-17 Trustees Of Dartmouth College Liver x receptor modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1042292A (en) * 1961-11-08 1966-09-14 Organon Labor Ltd 5ª‡-hydroxy-6ª‰-amino steroids and the preparation thereof
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
BE754360A (fr) * 1969-08-05 1971-02-03 Sandoz Sa Nouveaux derives de l'indole, leur preparation et medicaments contenantdes derives
HU168431B (hu) * 1972-07-27 1976-04-28
DE2526788A1 (de) * 1975-06-13 1976-12-23 Schering Ag Verfahren zur herstellung von d-homo- steroiden
HU172521B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh triamino-androstana i chetvertichnykh solejj
US4177190A (en) * 1975-08-01 1979-12-04 Richter Gedeon Vegyeszeti Gyar Rt. Diamino-androstanes and a process for the preparation of the said compounds
HU172522B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE3688559D1 (de) 1993-07-15
IL79211A0 (en) 1986-09-30
HU195972B (en) 1988-08-29
EP0208497B1 (en) 1991-03-06
EP0345471A2 (en) 1989-12-13
DE3688559T2 (de) 1993-09-16
US5410040A (en) 1995-04-25
EP0345471B1 (en) 1993-06-09
EP0208497A2 (en) 1987-01-14
AU586691B2 (en) 1989-07-20
ATE90358T1 (de) 1993-06-15
AU5936386A (en) 1987-01-08
JPS625992A (ja) 1987-01-12
EP0208497A3 (en) 1987-09-30
EP0345471A3 (en) 1990-02-07
ATE61374T1 (de) 1991-03-15
CA1314868C (en) 1993-03-23
DE3677841D1 (de) 1991-04-11

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee